복합부위통증증후군 환자의 인지기능 평가
Cognitive Assessment in Complex Regional Pain Syndrome Patients
1
조회
0
다운로드
6
인용
0
참고문헌
키워드
초록
Background: Complex regional pain syndrome (CRPS) is characterized by severe neuropathic pain and disability, which can result in psychological and behavioral dysfunction. The goal of the present study was to evaluate neurocognitive disability, and to assess the relationship between clinical variables and neuropsychological features in CRPS patients. Methods: We investigated the neuropsychological features of 15 CRPS I patients. The neuropsychological tests that we made comprised of a full intelligence quotient, memory quotient, trail-making test A, trail-making test B (TMT-B), and MMPI (Minnesota multiphasic personality inventory). Results: The results showed severe disability in performance on TMT-B. There was no significant correlation between specific cognitive variables and MMPI scales. Conclusions: Decreased performance on TMT-B which shows mental flexibility in the prefrontal lobe exists independently from depressive disorders in CRPS patients.
Abstract
Background: Complex regional pain syndrome (CRPS) is characterized by severe neuropathic pain and disability, which can result in psychological and behavioral dysfunction. The goal of the present study was to evaluate neurocognitive disability, and to assess the relationship between clinical variables and neuropsychological features in CRPS patients. Methods: We investigated the neuropsychological features of 15 CRPS I patients. The neuropsychological tests that we made comprised of a full intelligence quotient, memory quotient, trail-making test A, trail-making test B (TMT-B), and MMPI (Minnesota multiphasic personality inventory). Results: The results showed severe disability in performance on TMT-B. There was no significant correlation between specific cognitive variables and MMPI scales. Conclusions: Decreased performance on TMT-B which shows mental flexibility in the prefrontal lobe exists independently from depressive disorders in CRPS patients.
참고문헌 (22)
- Bruehl S, "Psychological differences between reflex sympathetic dystrophy and non-RSD chronic pain patients", Pain, 67, pp.107~114 (1996)
- Han TY, "The Correlation of the Mini-Mental State Examination (MMSE) and functional outcome in the stroke patients", J Korean Acad Rehabil Med, 16, pp.118~122 (1992)
- Reitan RM, "The effect of age and education transformations on neuropsychological test scores of persons with diffuse or bilateral brain damage", Appl Neuropsychol, 12, pp.181~189 (2005)
- Zimmerman ME, "Anterior cingulate subregion volumes and executive function in bipolar disorder", Bipolar Disord, 8, pp.281~288 (2006)
- Karp JF, "The relationship between pain and mental flexibility in older adult pain clinic patients", Pain Med, 7, pp.444~452 (2006)
- Baron R, "Complex regional pain syndromes-how do we escape the diagnostic trap?", Lancet, 364, pp.1739~1741 (2004)
- Strauss E, "A compendium of neuropsychological tests: administration, norms, and commentary. 3rd ed", pp.540~ (2006), Oxford University Press.
- Park DC, "Cognitive function in fibromyalgia patients", Arthritis Rheum, 44, pp.2125~2133 (2001)
- Reitan RM, "A selective and critical review of neuropsychological deficits and the frontal lobes", Neuropsychol Rev, 4, pp.161~198 (1994)
- Giovagnoli AR, "Trail making test: normative values from 287 normal adult controls", Ital J Neurol Sci, 17, pp.305~309 (1996)
- Crowe SF, "The differential contribution of mental tracking, cognitive flexibility, visual search, and motor speed to performance on parts A and B of the Trail Making Test", J Clin Psychol, 54, pp.585~591 (1998)
- Segalowitz SJ, "CNV evidence for the distinctiveness of frontal and posterior neural processes in a traumatic brain-injured population", J Clin Exp Neuropsychol, 14, pp.545~565 (1992)
- Moll J, "The cerebral correlates of set-shifting: an fMRI study of the trail making test", Arq Neuropsiquiatr, 60, pp.900~905 (2002)
- Zakzanis KK, "An fMRI study of the Trail Making Test", Neuropsychologia, 43, pp.1878~1886 (2005)
- Suwalska A, "Cognitive deficits in the bipolar affective disorder", Psychiatr Pol, 35, pp.657~668 (2001)
- Remy F, "Pain modulates cerebral activity during cognitive performance", Neuroimage, 19, pp.655~664 (2003)
- 문동언, "만성통증 환자에서 항우울제의 사용", The Korean Journal of Pain, 17(2), pp.9~9 (2004), 대한통증학회
- Harvey PD, "Comparative effects of risperidone and olanzapine on cognition in elderly patients with schizophrenia or schizoaffective disorder", Int J Geriatr Psychiatry, 18, pp.820~829 (2003)
- Wecker NS, "Age effects on executive ability", Neuropsychology, 14, pp.409~414 (2000)
- Roberts C, "Derived trail making test indices in a sample of sedative abusers: demographic effects", Int J Neurosci, 112, pp.985~994 (2002)
- King DJ, "The effect of neuroleptics on cognitive and psychomotor function. A preliminary study in healthy volunteers", Br J Psychiatry, 160, pp.647~653 (1992)
- Berman KF, "Physiologic dysfunction of dorsolateral prefrontal cortex in schizophrenia. II. Role of neuroleptic treatment, attention, and mental effort", Arch Gen Psychiatry, 43, pp.126~135 (1986)