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레진 계열 근관봉함재 Adseal의 세포독성에 관한 연구

Cytotoxicity of resin-vased root canal sealer,adseal

김희정|배광식|이우철|백승호|박한수
대한치과보존학회 (Korean Academy Of Conservative Dentistry)|2004.11|Restorative Dentistry and Endodontics|제29권 제6호|pp. 498-503

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참고문헌

주제분류치의학

초록

Abstract

The properties of ideal root canal sealers include the ability of sealing the total root canal system and no toxic effects to periradicular tissues. Cytotoxicity test using cell culture is a common screening method for evaluation of the biocompatibility of root canal sealers. The purpose of this study was to investigate the cytotoxic effect of newly developed resin-based sealer (Adseal 1, 2, and 3) comparing with those commercial resin-based sealers (AH26 and AH Plus), ZOE-based sealers (Tubliseal EWT, Pulp Canal Sealer EWT) and calcium hydroxide based sealer (Sealapex). An indirect contact test of cytotoxicity by agar diffusion was performed according to the international standard ISO 10993-5. L929 fibroblast cells were incubated at 37℃ in humidified 5% CO2-containing air atmosphere. The freshly mixed test materials were inserted in to glass rings of internal diameter 5mm and height 5mm placed on the agar. After the 24 hrs incubation period, the decolorization zones around the test materials were assessed using an inverted microscope with a calibrated screen. A Decolorization Index was determined for each specimen. Adseal 1, 2, and 3 did not exert any cytotoxic effects, whereas AH26, AH Plus, Tubliseal EWT, Pulp Canal Sealer EWT, and Sealapex produced mild cytotoxicity.

참고문헌 (26)

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관련 논문AI추천

Resin-Based Root Sealer의 생체 적합성 평가김형선, 문종현, 유미경, 이광원, 전성민대한턱관절교합학회 · 구강회복응용과학지2007 · 제23권 제1호레진계 근관충전실러의 방사선 불투과성 및 세포 독성에 대한 평가김창규, 류현욱, 민경산, 이병도, 장훈상, 홍찬의대한치과보존학회 · Restorative Dentistry and Endodontics2007 · 제32권 제5호신개발 인산칼슘계 근관 봉함재의 세포독성 및 유전독성에 관한 연구김희정, 배광식, 백승호대한치과보존학회 · Restorative Dentistry and Endodontics2006 · 제31권 제1호신개발 레진 계열 봉함제의 생체친화성에 관한 연구김용범, 배광식, 백승호대한치과보존학회 · Restorative Dentistry and Endodontics2002 · 제27권 제2호새로운 레진 계통의 근관봉함재의 독성과 항균 작용에 대한 연구박소영, 이우철, 임성삼대한치과보존학회 · Restorative Dentistry and Endodontics2003 · 제28권 제2호8종 root canal sealers의 경화 전, 후의 항균효과에 관한 연구이우철, ChernHLai, DennyYFang대한치과보존학회 · Restorative Dentistry and Endodontics2002 · 제27권 제2호

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