Modalities in managing postherpetic neuralgia
2
조회
0
다운로드
4
인용
0
참고문헌
키워드
초록
Postherpetic neuralgia (PHN) is the most troublesome side effect of Herpes Zoster (HZ), which mainly affects the elderly and immunocompromised populations. Despite the current advancement of treatments, PHN persists in many individuals influencing their daily activities and reducing their quality of life. Anticonvulsants, antidepressants, topical therapies including lidocaine and capsaicin, and opioids, are the most widely used therapies for the treatment of PHN. These medications come with their adverse effects, so they should be used carefully with the elderly or with patients with significant comorbidities. Other measures like botulinum toxin, nerve blocks, spinal cord stimulation, and radiofrequency have also contributed significantly to the management of PHN. However, the efficacy, safety, and tolerability of these invasive methods need to be carefully monitored when administering them. Early diagnosis and early initiation of treatment can reduce the burden associated with PHN. The zoster vaccine has effectively reduced the incidence of HZ and PHN. In this article, we discuss the treatment options available for the management of PHN, mainly focusing on the efficacy and safety of different therapeutic modalities. (Korean J Pain 2018; 31: 235-43)
Abstract
Postherpetic neuralgia (PHN) is the most troublesome side effect of Herpes Zoster (HZ), which mainly affects the elderly and immunocompromised populations. Despite the current advancement of treatments, PHN persists in many individuals influencing their daily activities and reducing their quality of life. Anticonvulsants, antidepressants, topical therapies including lidocaine and capsaicin, and opioids, are the most widely used therapies for the treatment of PHN. These medications come with their adverse effects, so they should be used carefully with the elderly or with patients with significant comorbidities. Other measures like botulinum toxin, nerve blocks, spinal cord stimulation, and radiofrequency have also contributed significantly to the management of PHN. However, the efficacy, safety, and tolerability of these invasive methods need to be carefully monitored when administering them. Early diagnosis and early initiation of treatment can reduce the burden associated with PHN. The zoster vaccine has effectively reduced the incidence of HZ and PHN. In this article, we discuss the treatment options available for the management of PHN, mainly focusing on the efficacy and safety of different therapeutic modalities. (Korean J Pain 2018; 31: 235-43)
참고문헌 (56)
- Gan EY, "Management of herpes zoster and post-herpetic neuralgia", Am J Clin Dermatol, 14, pp.77~85 (2013)[DOI]
- Massengill JS, "Practical considerations in the pharmacological treatment of postherpetic neuralgia for the primary care provider", J Pain Res, 7, pp.125~132 (2014)
- Mallick-Searle T, "Postherpetic neuralgia: epidemiology, pathophysiology, and pain management pharmacology", J Multidiscip Healthc, 9, pp.447~454 (2016)[DOI]
- Nalamachu S, "Diagnosing and managing postherpetic neuralgia", Drugs Aging, 29, pp.863~869 (2012)[DOI]
- Khadem T, "Therapeutic options for the treatment of postherpetic neuralgia: a systematic review", J Pain Palliat Care Pharmacother, 27, pp.268~283 (2013)[DOI]
- Hadley GR, "Post-herpetic neuralgia: a review", Curr Pain Headache Rep, 20, pp.17~ (2016)[DOI]
- Kawai K, "Systematic review of incidence and complications of herpes zoster: towards a global perspective", BMJ Open, 4, pp.e004833~ (2014)[DOI]
- Chen LK, "Looking back to move forward: a twenty-year audit of herpes zoster in Asia-Pacific", BMC Infect Dis, 17, pp.213~ (2017)[DOI]
- Werner RN, "European consensus-based (S2k) guideline on the management of herpes zoster - guided by the European Dermatology Forum (EDF) in cooperation with the European Academy of Dermatology and Venereology (EADV), Part 1: diagnosis", J Eur Acad Dermatol Venereol, 31, pp.9~19 (2017)[DOI]
- Young Hoon Jeon, "Herpes Zoster and Postherpetic Neuralgia: Practical Consideration for Prevention and Treatment", The Korean Journal of Pain, 28(3), pp.177~184 (2015), 대한통증학회
- Bader MS, "Herpes zoster: diagnostic, therapeutic, and preventive approaches", Postgrad Med, 125, pp.78~91 (2013)
- Johnson RW, "Postherpetic neuralgia", N Engl J Med, 371, pp.1526~1533 (2014)[DOI]
- Schmader K, "Herpes zoster", Clin Geriatr Med, 32, pp.539~553 (2016)[DOI]
- Haanpaa M, "Treating herpes zoster and postherpetic neuralgia", Pain Clin, 23, pp.1~8 (2015)
- Blom S, "Trigeminal neuralgia: its treatment with a new anticonvulsant drug (G-32883)", Lancet, 1, pp.839~840 (1962)
- Moore RA, "Pregabalin for acute and chronic pain in adults", Cochrane Database Syst Rev (2009)
- [URL]
- Meng FY, "Efficacy and safety of gabapentin for treatment of postherpetic neuralgia: a meta-analysis of randomized controlled trials", Minerva Anestesiol, 80, pp.556~567 (2014)
- [URL]
- Sang CN, "Gastroretentive gabapentin (G-GR) formulation reduces intensity of pain associated with postherpetic neuralgia (PHN)", Clin J Pain, 29, pp.281~288 (2013)[DOI]
- [URL]
- Lal R, "Population pharmacokinetics and pharmacodynamics of gabapentin after administration of gabapentin enacarbil", J Clin Pharmacol, 53, pp.29~40 (2013)[DOI]
- [URL]
- Ifuku M, "Replacement of gabapentin with pregabalin in postherpetic neuralgia therapy", Pain Med, 12, pp.1112~1116 (2011)[DOI]
- Zilliox LA, "Neuropathic pain", Continuum (Minneap Minn), 23, pp.512~532 (2017)
- Hempenstall K, "Analgesic therapy in postherpetic neuralgia: a quantitative systematic review", PLoS Med, 2, pp.e164~ (2005)[DOI]
- Enamandram M, "Chronic pain management in dermatology: a guide to assessment and nonopioid pharmacotherapy", J Am Acad Dermatol, 73, pp.563~573 (2015)[DOI]
- Harden RN, "Evidencebased guidance for the management of postherpetic neuralgia in primary care", Postgrad Med, 125, pp.191~202 (2013)
- Derry S, "Topical lidocaine for neuropathic pain in adults", Cochrane Database Syst Rev (2014)
- [URL]
- Krumova EK, "Lidocaine patch (5%) produces a selective, but incomplete block of <TEX>$A{\delta}$<", TEX> and C fibers, 2012, pp.153, 273~280
- Campbell BJ, "Systemic absorption of topical lidocaine in normal volunteers, patients with post-herpetic neuralgia, and patients with acute herpes zoster", J Pharm Sci, 91, pp.1343~1350 (2002)[DOI]
- Navez ML, "5% lidocaine medicated plaster for the treatment of postherpetic neuralgia: a review of the clinical safety and tolerability", Pain Ther, 4, pp.1~15 (2015)[DOI]
- Baron R, "5% lidocaine medicated plaster versus pregabalin in post-herpetic neuralgia and diabetic polyneuropathy: an open-label, non-inferiority two-stage RCT study", Curr Med Res Opin, 25, pp.1663~1676 (2009)[DOI]
- Baranidharan G, "A review of the high-concentration capsaicin patch and experience in its use in the management of neuropathic pain", Ther Adv Neurol Disorder, 6, pp.287~297 (2013)[DOI]
- Irving GA, "A multicenter, randomized, double-blind, controlled study of NGX-4010, a high-concentration capsaicin patch, for the treatment of postherpetic neuralgia", Pain Med, 12, pp.99~109 (2011)[DOI]
- [URL]
- Derry S, "Topical capsaicin (high concentration) for chronic neuropathic pain in adults", Cochrane Database Syst Rev (2017)
- Burness CB, "Capsaicin 8 % patch: a review in peripheral neuropathic pain", Drugs, 76, pp.123~134 (2016)[DOI]
- Raja SN, "Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial", Neurology, 59, pp.1015~1021 (2002)[DOI]
- Boureau F, "Tramadol in post-herpetic neuralgia: a randomized, double-blind, placebo-controlled trial", Pain, 104, pp.323~331 (2003)[DOI]
- Shackleton T, "The efficacy of botulinum toxin for the treatment of trigeminal and postherpetic neuralgia: a systematic review with meta-analyses", Oral Surg Oral Med Oral Pathol Oral Radiol, 122, pp.61~71 (2016)[DOI]
- Park J, "Botulinum toxin for the treatment of neuropathic pain", Toxins (Basel), 9 (2017)
- Ding XD, "Botulinum as a toxin for treating post-herpetic neuralgia", Iran J Public Health, 46, pp.608~611 (2017)
- 김현정, "Effects of applying nerve blocks to prevent postherpetic neuralgia in patients with acute herpes zoster: a systematic review and meta-analysis", The Korean Journal of Pain, 30(1), pp.3~17 (2017), 대한통증학회
- Ing MR, "Transcutaneous electrical nerve stimulation for chronic post-herpetic neuralgia", Int J Dermatol, 54, pp.476~480 (2015)[DOI]
- Lerman IR, "Novel high-frequency peripheral nerve stimulator treatment of refractory postherpetic neuralgia: a brief technical note", Neuromodulation, 18, pp.487~493 (2015)[DOI]
- Kim K, "Pulsed radiofrequency to the dorsal root ganglion in acute herpes zoster and postherpetic neuralgia", Pain Physician, 20, pp.E411~E418 (2017)
- Kim ED, "Comparison of efficacy of continuous epidural block and pulsed radiofrequency to the dorsal root ganglion for management of pain persisting beyond the acute phase of herpes zoster", PLoS One, 12, pp.e0183559~ (2017)[DOI]
- Shi Y, "Treatment of neuropathic pain using pulsed radiofrequency: a meta-analysis", Pain Physician, 19, pp.429~444 (2016)
- Yanamoto F, "The effects of temporary spinal cord stimulation (or spinal nerve root stimulation) on the management of early postherpetic neuralgia from one to six months of its onset", Neuromodulation, 15, pp.151~154 (2012)[DOI]
- 고영권, "Clinical Experiences on the Effect of Scrambler Therapy for Patients with Postherpetic Neuralgia", The Korean Journal of Pain, 26(1), pp.98~101 (2013), 대한통증학회
- Marineo G, "Scrambler therapy may relieve chronic neuropathic pain more effectively than guideline-based drug management: results of a pilot, randomized, controlled trial", J Pain Symptom Manage, 43, pp.87~95 (2012)[DOI]
- Harpaz R, "Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP)", MMWR Recomm Rep, 57, pp.1~30 (2008)
- [URL]
- 강동희, "Earlier treatment improves the chances of complete relief from postherpetic neuralgia", The Korean Journal of Pain, 30(3), pp.214~219 (2017), 대한통증학회
