Antimicrobial efficacy of QMix on Enterococcus faecalis infected root canals: a systematic review of in vitro studies
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Objectives: This study aimed to summarize the outcome of in vitro studies comparing the antibacterial effectiveness of QMix with other irrigants against Enterococcus faecalis. Materials and Methods: The research question was developed by using population, intervention, comparison, outcome, and study design framework. The literature search was performed using 3 electronic databases: PubMed, Scopus, and EBSCOhost until October 2019. The additional hand search was performed from the reference list of the eligible studies. The risk of bias of the studies was independently appraised using the revised Cochrane Risk of Bias tool (RoB 2.0). Results: Fourteen studies were included in this systematic review. The overall risk of bias for the selected studies was moderate. QMix was found to have a higher antimicrobial activity compared to 2% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), mixture of tetracycline isonomer, an acid and a detergent (MTAD), 0.2% Cetrimide, SilverSol/H2O2, HYBENX, and grape seed extract (GSE). QMix had higher antibacterial efficacy compared to NaOCl, only when used for a longer time (10 minutes) and with higher volume (above 3 mL). Conclusions: QMix has higher antibacterial activity than 17% EDTA, 2% CHX, MTAD, 0.2% Cetrimide, SilverSol/H2O2, HYBENX, GSE and NaOCl with lower concentration. To improve the effectiveness, QMix is to use for a longer time and at a higher volume.
Abstract
Objectives: This study aimed to summarize the outcome of in vitro studies comparing the antibacterial effectiveness of QMix with other irrigants against Enterococcus faecalis. Materials and Methods: The research question was developed by using population, intervention, comparison, outcome, and study design framework. The literature search was performed using 3 electronic databases: PubMed, Scopus, and EBSCOhost until October 2019. The additional hand search was performed from the reference list of the eligible studies. The risk of bias of the studies was independently appraised using the revised Cochrane Risk of Bias tool (RoB 2.0). Results: Fourteen studies were included in this systematic review. The overall risk of bias for the selected studies was moderate. QMix was found to have a higher antimicrobial activity compared to 2% sodium hypochlorite (NaOCl), 17% ethylenediaminetetraacetic acid (EDTA), 2% chlorhexidine (CHX), mixture of tetracycline isonomer, an acid and a detergent (MTAD), 0.2% Cetrimide, SilverSol/H2O2, HYBENX, and grape seed extract (GSE). QMix had higher antibacterial efficacy compared to NaOCl, only when used for a longer time (10 minutes) and with higher volume (above 3 mL). Conclusions: QMix has higher antibacterial activity than 17% EDTA, 2% CHX, MTAD, 0.2% Cetrimide, SilverSol/H2O2, HYBENX, GSE and NaOCl with lower concentration. To improve the effectiveness, QMix is to use for a longer time and at a higher volume.
참고문헌 (44)
- Vieira AR, "Dentinal tubule infection as the cause of recurrent disease and late endodontic treatment failure : a case report", J Endod, 38, pp.250~254 (2012)
- Nair PN, "Intraradicular bacteria and fungi in root-filled, asymptomatic human teeth with therapy-resistant periapical lesions: a long-term light and electron microscopic follow-up study", J Endod, 16, pp.580~588 (1990)
- Neelakantan P, "Biofilms in endodontics-current status and future directions", Int J Mol Sci, 18, pp.E1748~ (2017)
- Song M, "Analysis of the cause of failure in nonsurgical endodontic treatment by microscopic inspection during endodontic microsurgery", J Endod, 37, pp.1516~1519 (2011)
- Love RM, "Enterococcus faecalis--a mechanism for its role in endodontic failure", Int Endod J, 34, pp.399~405 (2001)
- Wang QQ, "Prevalence of Enterococcus faecalis in saliva and filled root canals of teeth associated with apical periodontitis", Int J Oral Sci, 4, pp.19~23 (2012)
- Zhang C, "Correlation between Enterococcus faecalis and persistent intraradicular infection compared with primary intraradicular infection : a systematic review", J Endod, 41, pp.1207~1213 (2015)
- Pinheiro ET, "Evaluation of root canal microorganisms isolated from teeth with endodontic failure and their antimicrobial susceptibility", Oral Microbiol Immunol, 18, pp.100~103 (2003)
- Rossi-Fedele G, "A preliminary study investigating the survival of tetracycline resistant Enterococcus faecalis after root canal irrigation with high concentrations of tetracycline", Int Endod J, 40, pp.772~777 (2007)
- Sedgley CM, "Survival of Enterococcus faecalis in root canals ex vivo", Int Endod J, 38, pp.735~742 (2005)
- Zehnder M, "Root canal irrigants", J Endod, 32, pp.389~398 (2006)
- Hülsmann M, "Chelating agents in root canal treatment : mode of action and indications for their use", Int Endod J, 36, pp.810~830 (2003)
- Weber CD, "The effect of passive ultrasonic activation of 2% chlorhexidine or 5.25% sodium hypochlorite irrigant on residual antimicrobial activity in root canals", J Endod, 29, pp.562~564 (2003)
- Johal S, "Comparison of the antimicrobial efficacy of 1.3% NaOCl", BioPure MTAD to 5.25% NaOCl, J Endod, pp.2007, 33[DOI]
- Siqueira JF Jr, "Optimising single-visit disinfection with supplementary approaches : a quest for predictability", Aust Endod J, 37, pp.92~98 (2011)
- Jose J, "Comparative evaluation of antimicrobial activity of QMix, 2.5% sodium hypochlorite, 2% chlorhexidine, guava leaf extract and aloevera extract against Enterococcus faecalis and candida albicans: an in-vitro study", J Clin Diagn Res, 10, pp.ZC20~ZC23 (2016)
- Goldman LB, "The efficacy of several irrigating solutions for endodontics : a scanning electron microscopic study", Oral Surg Oral Med Oral Pathol, 52, pp.197~204 (1981)
- Stojicic S, "Antibacterial and smear layer removal ability of a novel irrigant", QMiX. Int Endod J, 45, pp.363~371 (2012)
- Dai L, "The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris", J Endod, 37, pp.80~84 (2011)
- Zhang R, "Antibacterial and residual antimicrobial activities against Enterococcus faecalis biofilm: a comparison between EDTA, chlorhexidine, cetrimide, MTAD and QMix", Sci Rep, 5, pp.12944~ (2015)
- Liu Y, "In vitro comparison of antimicrobial effectiveness of QMix and other final irrigants in human root canals", Sci Rep, 5, pp.17823~ (2015)
- Bago Jurič I, "Antimicrobial efficacy of photodynamic therapy, Nd:YAG laser and QMiX solution against Enterococcus faecalis biofilm", Photodiagnosis Photodyn Ther, 13, pp.238~243 (2016)
- Elakanti S, "Comparative evaluation of antimicrobial efficacy of QMix™ 2 in 1, sodium hypochlorite, and chlorhexidine against Enterococcus faecalis and Candida albicans", J Conserv Dent, 18, pp.128~131 (2015)
- Vaid D, "Additive effect of photoactivated disinfection on the antibacterial activity of QMix 2in1 against 6-week Enterococcus faecalis biofilms : an in vitro study", J Conserv Dent, 20, pp.41~45 (2017)
- Cecchin D, "Evaluation of antimicrobial effectiveness and dentine mechanical properties after use of chemical and natural auxiliary irrigants", J Dent, 43, pp.695~702 (2015)
- Souza MA, "Effectiveness of final decontamination protocols against Enterococcus faecalis and its influence on bond strength of filling material to root canal dentin", Photodiagnosis Photodyn Ther, 17, pp.92~97 (2017)
- Wang Z, "Effectiveness of endodontic disinfecting solutions against young and old Enterococcus faecalis biofilms in dentin canals", J Endod, 38, pp.1376~1379 (2012)
- Ma J, "A new noninvasive model to study the effectiveness of dentin disinfection by using confocal laser scanning microscopy", J Endod, 37, pp.1380~1385 (2011)
- Wang Z, "Effect of smear layer against disinfection protocols on Enterococcus faecalis-infected dentin", J Endod, 39, pp.1395~1400 (2013)
- Ye WH, "Anti-biofilm efficacy of root canal irrigants against in-situ Enterococcus faecalis biofilms in root canals, isthmuses and dentinal tubules", J Dent, 79, pp.68~76 (2018)
- Souza MA, "Influence of ultrasonic activation using different final irrigants on antimicrobial activity, smear layer removal and bond strength of filling material", Aust Endod J, 45, pp.209~215 (2019)
- Balić M, "The efficacy of photon-initiated photoacoustic streaming and sonic-activated irrigation combined with QMiX solution or sodium hypochlorite against intracanal E. faecalis biofilm", Lasers Med Sci, 31, pp.335~342 (2016)
- Matos FS, "Effect of EDTA and QMIX ultrasonic activation on the reduction of microorganisms and endotoxins in ex vivo human root canals", Braz Dent J, 30, pp.220~226 (2019)
- Moher D, "Preferred reporting items for systematic reviews and meta-analyses : the PRISMA statement", PLoS Med, 6, pp.e1000097~ (2009)
- Higgins JP, "A revised tool for assessing risk of bias in randomized trials", Cochrane Database Syst Rev, 10, pp.S29~S31 (2016)
- Giardino L, "Antimicrobial effect and surface tension of some chelating solutions with added surfactants", Braz Dent J, 27, pp.584~588 (2016)
- Bortoluzzi EA, "Efficacy of 3D conforming nickel titanium rotary instruments in eliminating canal wall bacteria from oval-shaped root canals", J Dent, 43, pp.597~604 (2015)
- Batinić M, "Comparison of final disinfection protocols using antimicrobial photodynamic therapy and different irrigants after single-file reciprocating instrumentation against intracanal bacterial biofilm : an in vitro study", Photodiagnosis Photodyn Ther, 24, pp.153~157 (2018)
- Haapasalo M, "Irrigation in endodontics", Dent Clin North Am, 54, pp.291~312 (2010)
- Parmar D, "Bacterial localization and viability assessment in human ex vivo dentinal tubules by fluorescence confocal laser scanning microscopy", Int Endod J, 44, pp.644~651 (2011)
- Zapata RO, "Confocal laser scanning microscopy is appropriate to detect viability of Enterococcus faecalis in infected dentin", J Endod, 34, pp.1198~1201 (2008)
- Drake DR, "Bacterial retention in canal walls in vitro : effect of smear layer", J Endod, 20, pp.78~82 (1994)
- de Gregorio C, "Effect of EDTA, sonic, and ultrasonic activation on the penetration of sodium hypochlorite into simulated lateral canals: an in vitro study", J Endod, 35, pp.891~895 (2009)
- de Gregorio C, "Efficacy of different irrigation and activation systems on the penetration of sodium hypochlorite into simulated lateral canals and up to working length : an in vitro study", J Endod, 36, pp.1216~1221 (2010)