실험적 흰쥐 간 질환 모델의 이해 -형태학적 특징을 중심으로-

Abstract

Experimental liver disease models of rats have many similarities with those of humans, especially in morphological characteristics. Rat liver disease models can be categorized as models of hepatic fibrosis, hepatic stem cell and hepatocarcinogenesis. The purpose of this article is to review experimental liver disease models, with a major emphasis on morphologic features, including routine morphological, immunohistochemical, and electron microscopic features.