Intranodal Palisaded Myofibroblastoma with Desmin Expression - A Brief Case Report -
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Intranodal palisaded myofibroblastoma is a rare benign mesenchymal neoplasm of the lymph node. It is characterized by intranodal spindle cell proliferation along with amianthoid fibers and prominent hemorrhage. It has been rarely reported in South Korea. We report here on a case of palisaded myofibroblastoma that arose in the left inguinal lymph node. The tumor mass was well demarcated, and it was composed of a proliferation of benign-looking spindle cells. It showed focal hemorrhage and a fibrous pseudocapsule. The tumor cells displayed little pleomorphism, no mitotic count, and characteristic palisading nuclei and amianthoid fibers. The tumor cells were positive for smooth muscle actin, vimentin, and also for desmin, but they were negative for S-100 protein, supporting the diagnosis of myofibroblastoma.
Abstract
Intranodal palisaded myofibroblastoma is a rare benign mesenchymal neoplasm of the lymph node. It is characterized by intranodal spindle cell proliferation along with amianthoid fibers and prominent hemorrhage. It has been rarely reported in South Korea. We report here on a case of palisaded myofibroblastoma that arose in the left inguinal lymph node. The tumor mass was well demarcated, and it was composed of a proliferation of benign-looking spindle cells. It showed focal hemorrhage and a fibrous pseudocapsule. The tumor cells displayed little pleomorphism, no mitotic count, and characteristic palisading nuclei and amianthoid fibers. The tumor cells were positive for smooth muscle actin, vimentin, and also for desmin, but they were negative for S-100 protein, supporting the diagnosis of myofibroblastoma.
참고문헌 (7)
- Weiss SW, "Palisaded myofibroblastoma:a benign mesenchymal tumor of lymph node", Am J Surg Pathol, 13, pp.341~346 (1989)
- Suster S, "Intranodal hemorrhagic spindle-cell tumor with “amianthoid” fibers: report of six cases of a distinctive mesenchymal neoplasm of the inguinal region that simulates Kaposi’s sarcoma", Am J Surg Pathol, 13, pp.347~357 (1989)
- Lee JY, "Solitary spindle cell tumor with myoid differentiation of the lymph node", Arch Pathol Lab Med, 113, pp.547~550 (1989)
- Lioe TF, "A case of multicentric intranodal palisaded myofibroblatoma", Histopathology, 24, pp.173~175 (1994)
- Creager AJ, "Recurrent intranodal palisaded myofibroblastoma with metaplastic bone formation", Arch Pathol Lab Med, 123, pp.433~436 (1999)
- Bigotti G, "Mottolese M, Filippo FD. Selective location of palisaded myofibroblastoma with amianthoid fibers", J Clin Pathol, 44, pp.761~764 (1991)
- Hisaoka M, "Intranodal palisaded myofibroblastoma with so-called amianthoid fibers: a report of two cases with a review of the literature", Pathol Int, 48, pp.307~312 (1998)