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지방색전증과 동반된 폐포자충 폐렴 - 1예 보고 -

Pneumocystis jirovecii Pneumonia Accompanied with Fat Embolism - A Case Report -

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초록

Pneumocystis jirovecii is an atypical fungus that causes severe pneumonia in immune compromised patients. While Pneumocystis jirovecii pneumonia (PCP) is more commonly diagnosed in individuals who have HIV infection, it can occur in individuals with other forms of immunosuppression. Fat embolism most commonly develops after orthopedic injuries, but it has also been reported after other forms of trauma such as severe burns, closed-chest cardiac massage, and liposuction. Overlap in the clinical presentation of these diseases has not yet been reported. We report here on a case of PCP with fat embolism in 52-year-old female patient who had no obvious risk factors for HIV infection. Even if risk factors for HIV or other forms of immunosuppression are not present, PCP can also be seen in patients who present with fat embolism, and the clinical presentation of both conditions can overlap.

Abstract

Pneumocystis jirovecii is an atypical fungus that causes severe pneumonia in immune compromised patients. While Pneumocystis jirovecii pneumonia (PCP) is more commonly diagnosed in individuals who have HIV infection, it can occur in individuals with other forms of immunosuppression. Fat embolism most commonly develops after orthopedic injuries, but it has also been reported after other forms of trauma such as severe burns, closed-chest cardiac massage, and liposuction. Overlap in the clinical presentation of these diseases has not yet been reported. We report here on a case of PCP with fat embolism in 52-year-old female patient who had no obvious risk factors for HIV infection. Even if risk factors for HIV or other forms of immunosuppression are not present, PCP can also be seen in patients who present with fat embolism, and the clinical presentation of both conditions can overlap.

참고문헌 (7)

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  2. Taviloglu K, "Fat embolism syndrome", Surg Today, 37, pp.5~8 (2007)
  3. Famularo G, "Pulmonary embolism after intra-articular injection of methylprednisolone and hyaluronate", Clin Exp Rheumatol, 19, pp.355~ (2001)
  4. Case records of the Massachusetts General Hospital, "Weekly clinicopathological exercises. Case 23-1998. Tachypnea, changed mental status, and pancytopenia in an elderly man with treated lymphoma", N Engl J Med, 339, pp.254~261 (1998)
  5. Simkins J, "Pulmonary embolism in patients with acquired immunodeficiency syndrome presenting with clinical picture of Pneumocystis jirovecii pneumonia: report of two cases", Scand J Infect Dis, 39, pp.634~636 (2007)
  6. Medrano FJ, "Pneumocystis jirovecii in general population", Emerg Infect Dis, 11, pp.245~250 (2005)
  7. Stringer JR, "A new name (Pneumocystis jirovecii) for Pneumocystis from humans", Emerg Infect Dis, 8, pp.891~896 (2002)

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