간에 발생한 고립섬유종양 1예 보고
Solitary Fibrous Tumor of the Liver - A Case Report -
1
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Solitary fibrous tumor is an uncommon neoplasm of mesenchymal origin that primarily affects the pleura. This tumor has been rarely found in liver parenchyma. We present an additional case of a solitary fibrous tumor in the liver of a 46-year-old woman. A contrast-enhanced magnetic resonance image revealed a well-defined round hepatic mass with strong homogeneous enhancement on arterial phase imaging. The tumor was composed of cytologically bland spindle cells with alternating hypercellular and hypocellular sclerotic areas. Immunohistochemistry indicated that the tumor cells were positive for vimentin, CD34, CD99 and smooth muscle actin, but negative for cytokeratin, human melanoma black 45, CD117, bcl-2, and S-100 protein.
Abstract
Solitary fibrous tumor is an uncommon neoplasm of mesenchymal origin that primarily affects the pleura. This tumor has been rarely found in liver parenchyma. We present an additional case of a solitary fibrous tumor in the liver of a 46-year-old woman. A contrast-enhanced magnetic resonance image revealed a well-defined round hepatic mass with strong homogeneous enhancement on arterial phase imaging. The tumor was composed of cytologically bland spindle cells with alternating hypercellular and hypocellular sclerotic areas. Immunohistochemistry indicated that the tumor cells were positive for vimentin, CD34, CD99 and smooth muscle actin, but negative for cytokeratin, human melanoma black 45, CD117, bcl-2, and S-100 protein.
참고문헌 (7)
- Chan JK, "Solitary fibrous tumour:everywhere,and a diagnosis in vogue", Histopathology, 31, pp.568~576 (1997)
- Perini MV, "Solitary fibrous tumor of the liver:report of a rare case and review of the literature", Int J Surg, 6, pp.396~399 (2008)
- 곽수영, "간에서 발생한 고립 섬유종 1예", The Korean Journal of Hepatology, 13(4), pp.560~564 (2007), 대한간학회
- Schirosi L, "Pleuro-pulmonary solitary fibrous tumors:a clinicopathologic,immunohistochemical,and molecular study of 88 cases confirming the prognostic value of de Perrot staging system and p53 expression,and evaluating the role of c-kit,BRAF,PDGFRs(alpha", beta),c-met,and EGFR, 2008, pp.32, 1627~1642
- Yilmaz S, "Giant solitary fibrous tumor of the liver with metastasis to the skeletal system successfully treated with trisegmentectomy", Dig Dis Sci, 45, pp.168~174 (2000)
- Chan G, "Malignant transformation of a solitary fibrous tumor of the liver and intractable hypoglycemia", J Hepatobiliary Pancreat Surg, 14, pp.595~599 (2007)
- Kandpal H, "Solitary fibrous tumour of the liver: a rare imaging diagnosis using MRI and diffusion-weighted imaging", Br J Radiol, 81, pp.e282~e286 (2008)