Fine-Needle Aspiration Cytology of Carcinosarcoma in the Salivary Gland: An Extremely Rare Case Report
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Carcinosarcoma of the salivary gland is an extremely rare tumor that is composed of both ,malignant epithelial and mesenchymal components. Diagnosing carcinosarcoma with fine-needle aspiration cytology is challenging because of its overlapping cytomorphologic characteristics with other high-grade malignant salivary gland tumors. Among the many features, including pleomorphic oncocytoid epithelial components, necrotic background, and mitoses, recognizing the singly scattered atypical spindle cells is most essential in carcinosarcoma. We present a case of a 66-year-old male patient with characteristic features of carcinosarcoma, who was successfully treated by wide local excision and subsequent radiation therapy.
Abstract
Carcinosarcoma of the salivary gland is an extremely rare tumor that is composed of both ,malignant epithelial and mesenchymal components. Diagnosing carcinosarcoma with fine-needle aspiration cytology is challenging because of its overlapping cytomorphologic characteristics with other high-grade malignant salivary gland tumors. Among the many features, including pleomorphic oncocytoid epithelial components, necrotic background, and mitoses, recognizing the singly scattered atypical spindle cells is most essential in carcinosarcoma. We present a case of a 66-year-old male patient with characteristic features of carcinosarcoma, who was successfully treated by wide local excision and subsequent radiation therapy.
참고문헌 (10)
- King OH Jr., "Carcinosarcoma of accessory salivary gland: first report of a case", Oral Surg Oral Med Oral Pathol, 23, pp.651~659 (1967)[DOI]
- Keh SM, "Primary carcinosarcoma of the parotid gland", Clin Pract, 1, pp.e117~ (2011)
- Schmidt RL, "A systematic review and meta-analysis of the diagnostic accuracy of fine-needle aspiration cytology for parotid gland lesions", Am J Clin Pathol, 136, pp.45~59 (2011)[DOI]
- Schmidt RL, "A systematic review and meta-analysis of the diagnostic accuracy of frozen section for parotid gland lesions", Am J Clin Pathol, 136, pp.729~738 (2011)[DOI]
- Griffith CC, "Salivary gland tumor fineneedle aspiration cytology: a proposal for a risk stratification classification", Am J Clin Pathol, 143, pp.839~853 (2015)[DOI]
- Naib ZM, "Cytopathology" (1996), Little Brown & Company
- Marcotullio D, "Mucoepidermoid carcinoma associated with osteosarcoma in a true malignant mixed tumor of the submandibular region", Case Rep Otolaryngol, 2015, pp.694684~ (2015)
- Stephen J, "True malignant mixed tumors (carcinosarcoma) of salivary glands", Oral Surg Oral Med Oral Pathol, 61, pp.597~602 (1986)[DOI]
- Bleiweiss IJ, "Carcinosarcoma of the submandibular salivary gland. Immunohistochemical findings", Cancer, 69, pp.2031~2035 (1992)[DOI]
- Kwon MY, "True malignant mixed tumor (carcinosarcoma) of parotid gland with unusual mesenchymal component: a case report and review of the literature", Arch Pathol Lab Med, 125, pp.812~815 (2001)
