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Intravascular Leiomyosarcoma of the Femoral Vein - A Case Report -

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초록

Intravascular leiomyosarcomas of the femoral vein are extremely rare. Our patient was initially diagnosed with a deep vein thrombosis based on ultrasonography and venography. The thrombectomy specimen consisted of typical spindle cells with variable anaplasia arranged in a fasciculating and interlacing pattern. The final diagnosis was proved to be an intravascular leiomyosarcoma confirmed by immunohistochemical studies for smooth muscle actin, desmin, vimentin, CD34 and CD68.

Abstract

Intravascular leiomyosarcomas of the femoral vein are extremely rare. Our patient was initially diagnosed with a deep vein thrombosis based on ultrasonography and venography. The thrombectomy specimen consisted of typical spindle cells with variable anaplasia arranged in a fasciculating and interlacing pattern. The final diagnosis was proved to be an intravascular leiomyosarcoma confirmed by immunohistochemical studies for smooth muscle actin, desmin, vimentin, CD34 and CD68.

참고문헌 (8)

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  2. Weiss SW, "Soft tissue tumors. 4th ed", pp.742~745 (2001), Mosby
  3. Kevorikian J, "Leiomyosarcoma of the large arteries and veins", Surgery, 73, pp.390~400 (1973)
  4. Mingoli A, "International registry of inferior vena cava leiomyosarcoma: analysis of a world series on 218 patients", Anticancer Res, 16, pp.3201~3205 (1996)
  5. Roy C, "Leiomyosarcoma of the femoral vein: imaging findings", Am J Roentgenol, 160, pp.1125~1126 (1993)
  6. Obuobie K, "An abnormal venous clot", Lancet, 357, pp.1334~ (2001)
  7. Gow CH, "Primary venous leiomyosarcoma of the femoral vein leading to metastases of scalp and lung", Clin Oncol (R Coll Radiol), 17, pp.201~ (2005)
  8. Monig SP, "Diagnosis, treatment and prognosis of the leiomyosarcoma of the inferior vena cava: three cases and summary of published reports", Eur J Surg, 161, pp.231~235 (1995)

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