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흰쥐 악하선에서 나트륨 운반체 및 수분 통로의 자율신경성 조절

Sympathetic and parasympathetic regulation of sodium transporters and water channels in rat submandibular gland

유선열|정현
대한구강악안면외과학회 (Korean Association Of Oral And Maxillofacial Surgeons)|2006.02|대한구강악안면외과학회지 (Journal of the Korean Association of Oral and Maxillofacial Surgeons)|제32권 제1호|pp. 1-7

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참고문헌

주제분류치의학

초록

Abstract

The present study was aimed to explore the role of sympathetic and parasympathetic nerves in the regulation of sodium transporters and water channels in the salivary gland. Rats were denervated of their sympathetic and parasympathetic nerves to the submandibular gland, and the glandular expression of sodium transporters and water channels was determined by Western blot analysis. The expression of either α1 or β1 subunit of Na, K-ATPase was not significantly affected either by the sympathetic or by the parasympathetic denervation. The expression of subunits of epithelial sodium channels was significantly increased both in the denervated and contralateral glands either by the sympathetic or by the parasympathetic denervation. Neither the sympathetic nor the parasympathetic denervation significantly altered the expression of aquaporin-1 (AQP1). Nor was the expression of AQP4 affected significantly by the parasympathetic or the sympathetic denervation. On the contrary, the expression of AQP5 was significantly increased not only by the parasympathetic but also by the sympathetic denervation. These results suggest that sympathetic and parasympathetic nerves have tonic regulatory effects on the regulation of certain sodium transporters and AQP water channels in the salivary gland.

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관련 논문AI추천

흰쥐 악하선에서 교감신경과 부교감신경에 의한 나트륨 운반체 및 수분 통로 조절김기영, 유선열대한구강악안면외과학회 · 대한구강악안면외과학회지2005 · 제31권 제1호Purinergic Receptors Play Roles in Secretion of Rat von Ebner Salivary Gland김경년, 김상희, 정기명, 조영경대한구강생물학회 · International Journal of Oral Biology2006 · 제31권 제4호Swelling-activated Cl- Channels in Human Salivary Gland Acinar Cells김성민, 박경표, 정지훈, Gae-Sig Chun, Jaehyun Sim, Jong-Ho Lee, Se-Young Choi대한구강생물학회 · International Journal of Oral Biology2009 · 제34권 제3호Cholinergic and neurokinergic agonist-induced Ca2+ responses in rat von Ebner's gland acinar cells김경년, 김상희, 정기명, 조영경, Stephen D. Roper대한구강생물학회 · International Journal of Oral Biology2006 · 제31권 제3호흰쥐 타액선내에서의 Dendroapis Natriuretic Peptide(DNP)의 분포김재곤, 박병건, 백병주, 이영수대한소아치과학회 · 대한소아치과학회지2001 · 제28권 제3호악하선 분비관의 결찰 후 타액선 조직의 변화정인교, 차승만대한구강악안면외과학회 · 대한구강악안면외과학회지2005 · 제31권 제5호

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