본문 바로가기
KERD
논문KCI 등재

Tooth-derived bone graft material

2

조회

0

다운로드

5

인용

0

참고문헌

키워드

주제분류치의학

초록

With successful extraction of growth factors and bone morphogenic proteins (BMPs) from mammalian teeth, many researchers have supported development of a bone substitute using tooth-derived substances. Some studies have also expanded the potential use of teeth as a carrier for growth factors and stem cells. A broad overview of the published findings with regard to tooth-derived regenerative tissue engineering technique is outlined. Considering more than 100 published papers, our team has developed the protocols and techniques for processing of bone graft material using extracted teeth. Based on current studies and studies that will be needed in the future, we can anticipate development of scaffolds, homogenous and xenogenous tooth bone grafts, and dental restorative materials using extracted teeth.

Abstract

With successful extraction of growth factors and bone morphogenic proteins (BMPs) from mammalian teeth, many researchers have supported development of a bone substitute using tooth-derived substances. Some studies have also expanded the potential use of teeth as a carrier for growth factors and stem cells. A broad overview of the published findings with regard to tooth-derived regenerative tissue engineering technique is outlined. Considering more than 100 published papers, our team has developed the protocols and techniques for processing of bone graft material using extracted teeth. Based on current studies and studies that will be needed in the future, we can anticipate development of scaffolds, homogenous and xenogenous tooth bone grafts, and dental restorative materials using extracted teeth.

참고문헌 (104)

  1. Yoshida T, "Cell lineage in mammalian craniofacial mesenchyme", Mech Dev, 125, pp.797~808 (2008)
  2. Morrison SJ, "Prospective identification, isolation by flow cytometry, and in vivo self-renewal of multipotent mammalian neural crest stem cells", Cell, 96, pp.737~749 (1999)
  3. Stevens A, "Human dental pulp stem cells differentiate into neural crest-derived melanocytes and have label-retaining and sphere-forming abilities", Stem Cells Dev, 17, pp.1175~1184 (2008)
  4. Arthur A, "Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues", Stem Cells, 26, pp.1787~1795 (2008)
  5. Reddi AH, "Bone matrix in the solid state: geometric influence on differentiation of fibroblasts", Adv Biol Med Phys, 15, pp.1~18 (1974)
  6. Huggins C, "Transformation of fibroblasts by allogeneic and xenogeneic transplants of demineralized tooth and bone", J Exp Med, 132, pp.1250~1258 (1970)
  7. Urist MR, "Bone morphogenetic protein", J Dent Res, 50, pp.1392~1406 (1971)
  8. Kawai T, "Bovine tooth-derived bone morphogenetic protein", J Dent Res, 68, pp.1069~1074 (1989)
  9. Bessho K, "Purification of rabbit bone morphogenetic protein derived from bone, dentin, and wound tissue after tooth extraction", J Oral Maxillofac Surg, 48, pp.162~169 (1990)
  10. Bessho K, "Comparison of bone matrix-derived bone morphogenetic proteins from various animals", J Oral Maxillofac Surg, 50, pp.496~501 (1992)
  11. Feng JQ, "Genomic organization, chromosomal mapping, and promoter analysis of the mouse dentin sialophosphoprotein (Dspp) gene, which codes for both dentin sialoprotein and dentin phosphoprotein", J Biol Chem, 273, pp.9457~9464 (1998)
  12. Ritchie HH, "Six decades of dentinogenesis research. Historical and prospective views on phosphophoryn and dentin sialoprotein", Eur J Oral Sci, 106(Suppl 1), pp.211~220 (1998)
  13. Hoeppner LH, "Runx2 and bone morphogenic protein 2 regulate the expression of an alternative Lef1 transcript during osteoblast maturation", J Cell Physiol, 221, pp.480~489 (2009)
  14. Handschin AE, "Cbfa-1 (Runx-2) and osteocalcin expression by human osteoblasts in heparin osteoporosis in vitro", Clin Appl Thromb Hemost, 12, pp.465~472 (2006)
  15. Ye L, "Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development", J Biol Chem, 279, pp.19141~19148 (2004)
  16. Kim YK, "Analysis of the inorganic component of autogenous tooth bone graft material", J Nanosci Nanotechnol, 11, pp.7442~7445 (2011)
  17. 김경욱, "자가치아골이식재의 결정구조 분석: X선 회절 분석", 대한구강악안면외과학회지, 37(3), pp.225~228 (2011), 대한구강악안면외과학회
  18. Lindsay S. Karfeld-Sulzer, "Biomaterial development for oral and maxillofacial bone regeneration", 대한구강악안면외과학회지, 38(5), pp.264~270 (2012), 대한구강악안면외과학회
  19. Urist MR, "Bone: formation by autoinduction", Science, 150, pp.893~899 (1965)
  20. Hanamura H, "Solubilized bone morphogenetic protein (BMP) from mouse osteosarcoma and rat demineralized bone matrix", Clin Orthop Relat Res, 148, pp.281~290 (1980)
  21. Sampath TK, "Homology of bone-inductive proteins from human, monkey, bovine, and rat extracellular matrix", Proc Natl Acad Sci U S A, 80, pp.6591~6595 (1983)
  22. Butler WT, "Noncollagenous proteins of a rat dentin matrix possessing bone morphogenetic activity", J Dent Res, 56, pp.228~232 (1977)
  23. Conover MA, "Dentin matrix morphogenetic protein, In The chemistry and biology of mineralized connective tissues: Proceedings of the First International Conference on the Chemistry and Biology of Mineralized Connective Tissues", Elsevier-North Holland Inc, pp.597~606 (1981)
  24. Chung PH, "Method for extracting tooth protein from extracted tooth", Korea Intellectual Property Rights Information Service. Patent. Application No. 10-2002-0008789, ~
  25. Chung PH, "Tooth protein extracted from extracted tooth and method for using the same", Korea intellectual property rights information service. Patent. Application No. 10-2004-0 051812, ~
  26. Chiba M, "Experimental studies of bone morphogenetic protein derived from bovine tooth", Jpn J Oral Maxillofac Surg, 34, pp.1557~1566 (1988)
  27. Urist MR, "Dentin, bone, and osteosarcoma tissue bone morphogenetic proteins", Prog Clin Biol Res, 101, pp.61~81 (1982)
  28. Bessho K, "Analysis of bone morphogenetic protein (BMP) derived from human and bovine bone matrix", Clin Orthop Relat Res, 268, pp.226~234 (1991)
  29. Bessho K, "Human dentin-matrix-derived bone morphogenetic protein", J Dent Res, 70, pp.171~175 (1991)
  30. Ito K, "Analysis of bone morphogenetic protein in human dental pulp tissues", Arch Bioceramics Res, 8, pp.166~169 (2008)
  31. Chae YP, "A histologic study on the repair of rat calvarial critical size defect with bovine bone morphogenetic protein (b-BMP)", J Korean Assoc Oral Maxillofac Surg, 23, pp.290~303 (1997)
  32. Kim BR, "Comparison of bone inducing process of porcine bone matrix-derived bmp combined with the following, freeze-dried allogeneic bone, surface demineralized allogeneic bone, and demineralized allogeneic bone powder in rats", J Korean Assoc Oral Maxillofac Surg, 24, pp.380~395 (1998)
  33. Oh DW, "Histologic evaluation of the ectopic bone formation induced by partially purified BMP-fibrous glass membrane complex", J Korean Assoc Oral Maxillofac Surg, 22, pp.86~100 (1996)
  34. 남정훈, "Matrix metalloproteinase(MMP) sensitive hyaluronic acid hydrogel-nanoparticle complex와 rhBMP-2를 이용한 골재생", 대한구강악안면외과학회지, 35(3), pp.137~145 (2009), 대한구강악안면외과학회
  35. 김선종, "Effects of Polycaprolactone-Tricalcium Phosphate, Recombinant Human Bone Morphogenetic Protein-2 and Dog Mesenchymal Stem Cells on Bone Formation: Pilot Study in Dogs", Yonsei Medical Journal, 50(6), pp.825~831 (2009), 연세대학교의과대학
  36. Lee JH, "The induction of bone formation in rat calvarial defects and subcutaneous tissues by recombinant human BMP-2, produced in Escherichia coli", Biomaterials, 31, pp.3512~3519 (2010)
  37. Schmidt-Schultz TH, "Intact growth factors are conserved in the extracellular matrix of ancient human bone and teeth: a storehouse for the study of human evolution in health and disease", Biol Chem, 386, pp.767~776 (2005)
  38. Gao J, "Expression of transforming growth factor-beta 1 (TGF-beta1) in the developing periodontium of rats", J Dent Res, 77, pp.1708~1716 (1998)
  39. Finkelman RD, "Quantitation of growth factors IGF-I, SGF", IGF-II, and TGF-beta in human dentin, 1990, pp.5, 717~723
  40. Rocha LB, "Biocompatibility of anionic collagen matrix as scaffold for bone healing", Biomaterials, 23, pp.449~456 (2002)
  41. Rosa FP, "Tissue response to polyanionic collagen: elastin matrices implanted in rat calvaria", Biomaterials, 24, pp.207~212 (2003)
  42. Maki F, "Bone healing in large mandibular defects without periosteum in adult rabbits: a new application of collagenous sponge for bone regene-ration", J Hard Tissue Biol, 9, pp.56~62 (2000)
  43. Nampo T, "A new method for alveolar bone repair using extracted teeth for the graft material", J Periodontol, 81, pp.1264~1272 (2010)
  44. Linde A, "Dentin matrix proteins: composition and possible functions in calcification", Anat Rec, 224, pp.154~166 (1989)
  45. Gongloff RK, "Vital root retention. A 5-year experience", Int J Oral Maxillofac Surg, 15, pp.33~38 (1986)
  46. Fareed K, "Vital root retention: a clinical procedure", J Prosthet Dent, 62, pp.430~434 (1989)
  47. Freedman GL, "Intentional partial odontectomy: report of case", J Oral Maxillofac Surg, 50, pp.419~421 (1992)
  48. Tsukamoto-Tanaka H, "Histochemical and immunocytochemical study of hard tissue formation in dental pulp during the healing process in rat molars after tooth replantation", Cell Tissue Res, 325, pp.219~229 (2006)
  49. Takamori Y, "Capacity of dental pulp differentiation in mouse molars as demonstrated by allogenic tooth transplantation", J Histochem Cytochem, 56, pp.1075~1086 (2008)
  50. Hasegawa T, "Influence of extended operation time and of occlusal force on determination of pulpal healing pattern in replanted mouse molars", Cell Tissue Res, 329, pp.259~272 (2007)
  51. Bang G, "Bone induction in excavation chambers in matrix of decalcified dentin", Arch Surg, 94, pp.781~789 (1967)
  52. Yeomans JD, "Bone induction by decalcified dentine implanted into oral, osseous and muscle tissues", Arch Oral Biol, 12, pp.999~1008 (1967)
  53. Carvalho VA, "Histomor-phometric analysis of homogenous demineralized dentin matrix as osteopromotive material in rabbit mandibles", Int J Oral Maxillofac Implants, 19, pp.679~686 (2004)
  54. Gomes MF, "Homogenous demineralized dentin matrix for application in cranioplasty of rabbits with alloxan-induced diabetes: histomorphometric analysis", Int J Oral Maxillofac Implants, 22, pp.939~947 (2007)
  55. Bessho K, "Purification of bone morphogenetic protein derived from bovine bone matrix", Biochem Biophys Res Commun, 165, pp.595~601 (1989)
  56. Nilsson OS, "Bone repair induced by bone morphogenetic protein in ulnar defects in dogs", J Bone Joint Surg Br, 68, pp.635~642 (1986)
  57. Sato K, "Induced regeneration of calvaria by bone morphogenetic protein (BMP) in dogs", Clin Orthop Relat Res, 197, pp.301~311 (1985)
  58. Urist MR, "Experimental delivery systems for bone morphogenetic protein, In Handbook of biomaterials and applications. Section 3: Orthopaedic biomaterials applications", pp.1093~1133 (1995), Marcel Dekker
  59. Herford AS, "Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2)", J Oral Maxillofac Surg, 66, pp.616~624 (2008)
  60. Jung RE, "Hämmerle CH. Bone morphogenetic protein-2 enhances bone formation when delivered by a synthetic matrix containing hydroxyapatite", tricalciumphosphate, 2008, pp.19, 188~195
  61. Boerckel JD, "Effects of protein dose and delivery system on BMP-mediated bone regeneration", Biomaterials, 32, pp.5241~5251 (2011)
  62. Ike M, "Recycled dentin root matrix for a carrier of recombinant human bone morphogenetic protein", J Oral Implantol, 24, pp.124~132 (1998)
  63. Yagihashi K, "Demineralized dentin matrix acts as a scaffold for repair of articular cartilage defects", Calcif Tissue Int, 84, pp.210~220 (2009)
  64. Murata M, "Bone engineering using human demineralized dentin matrix and recombinant human BMP-2", Hard Tissue Biol, 14, pp.80~81 (2005)
  65. Masaru Murata, "Biochemical and histo-morphometrical analyses of bone and cartilage induced by human decalcified dentin matrix and BMP-2", 구강생물학연구, 35(1), pp.9~14 (2011), 구강생물학연구소
  66. Urist MR, "Bone histogenesis and morphogenesis in implants of demineralized enamel and dentin", J Oral Surg, 29, pp.88~102 (1971)
  67. Inoue T, "Induction of cartilage and bone by dentin demineralized in citric acid", J Periodontal Res, 21, pp.243~255 (1986)
  68. Murata M, "Human acid-insoluble dentin with BMP-2 accelerates boneinduction in subcutaneous and intramuscular tissues", J Ceram Soc Jpn, 118, pp.438~441 (2010)
  69. Bang G, "Induction of heterotopic bone formation by demineralized dentin in guinea pigs: antigenicity of the dentin matrix", J Oral Pathol, 1, pp.172~185 (1972)
  70. Bang G, "Induction of heterotopic bone formation by demineralized dentin: an experimental model in guinea pigs", Scand J Dent Res, 81, pp.240~250 (1973)
  71. Urist MR, "Inductive substrates for bone formation", Clin Orthop Relat Res, 59, pp.59~96 (1968)
  72. Huggins CB, "Dentin matrix transformation: rapid induction of alkaline phosphatase and cartilage", Science, 167, pp.896~898 (1970)
  73. Reddi AH, "Biochemical sequences in the transformation of normal fibroblasts in adolescent rats", Proc Natl Acad Sci U S A, 69, pp.1601~1605 (1972)
  74. Reddi AH, "Collagenous bone matrix-induced endochondral ossification hemopoiesis", J Cell Biol, 69, pp.557~572 (1976)
  75. Urist MR, "Bone cell differentiation and growth factors", Science, 220, pp.680~686 (1983)
  76. Tazaki J, "Autograft of human tooth and demineralized dentin matricesfor bone augmentation", J Ceram Soc Jpn, 118, pp.442~445 (2010)
  77. Lee HJ, "Quantitative analysis of proliferation and differentiation of MG-63 cell line on the bone grafting material using human tooth", 박사, pp.2011
  78. Kim YK, "Development of a novel bone grafting material using autogenous teeth", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 109, pp.496~503 (2010)
  79. 김영균, "구성성분별 골이식재의 분류와 임상적용", 대한치과의사협회지, 48(4), pp.263~274 (2010), 대한치과의사협회
  80. 정혜린, "미니피그에서 자가치아뼈 이식의 골형성 효과에 대한 연구", 대한구강악안면외과학회지, 37(5), pp.375~379 (2011), 대한구강악안면외과학회
  81. Catanzaro-Guimarães SA, "Osteogenic potential of autogenic demineralized dentin implanted in bony defects in dogs", Int J Oral Maxillofac Surg, 15, pp.160~169 (1986)
  82. Gomes MF, "Histo-logic evaluation of the osteoinductive property of autogenous demi-neralized dentin matrix on surgical bone defects in rabbit skulls using human amniotic membrane for guided bone regeneration", Int J Oral Maxillofac Implants, 16, pp.563~571 (2001)
  83. Gomes MF, "Autogenous demineralized dentin matrix for tissue engineering applications: radiographic and histomorphometric studies", Int J Oral Maxillofac Implants, 17, pp.488~497 (2002)
  84. Gomes MF, "Densitometric analysis of the autogenous demineralized dentin matrix on the dental socket wound healing process in humans", Braz Oral Res, 20, pp.324~330 (2006)
  85. Murata M, "Acid-insoluble human dentin as carrier material for recombinant human BMP-2", J Biomed Mater Res A, 100, pp.571~577 (2012)
  86. Ryu SY, "Effects of demineralized dentin matrix on osseointegration of implants in dogs", J Korean Assoc Oral Maxillofac Surg, 22, pp.15~27 (1996)
  87. Shapoff CA, "The effect of particle size on the osteogenic activity of composite grafts of allogeneic freeze-dried bone and autogenous marrow", J Periodontol, 51, pp.625~630 (1980)
  88. Bhaskar SN, "Tissue reaction to intrabony ceramic implants", Oral Surg Oral Med Oral Pathol, 31, pp.282~289 (1971)
  89. Hosny M, "Osteoinduction in young and old rats using demineralized bone powder allografts", J Oral Maxillofac Surg, 43, pp.925~931 (1985)
  90. Murata M, "Human dentin as novel biomaterial for bone regeneration, In Biomaterials-physics and chemistry", pp.127~140 (2011), InTech
  91. Miyata Y, "An experimental study of bone grafting using rat milled tooth", Int J Oral Maxillofac Implants, 26, pp.1210~1216 (2011)
  92. Kim SG, "Grafting of large defects of the jaws with a particulate dentin-plaster of paris combination", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 88, pp.22~25 (1999)
  93. Jong-Yub Kim, "Bone Healing Capacity of Demineralized Dentin Matrix Materials in a Mini-pig Cranium Defect", 대한치의학회 영문학회지, 5(1), pp.21~28 (2012), 대한치의학회
  94. Kim YK, "The evaluation of postoperative safety of autogenous teeth bone graft", J Korean Acad Implant Dent, 28, pp.29~35 (2009)
  95. 김영균, "자가치아골이식재를 이용한 발치창 보존 및 재건술", Maxillofacial Plastic Reconstructive Surgery, 33(3), pp.264~269 (2011), 대한악안면성형재건외과학회
  96. 김영균, "치조능확장술과 자가치아골이식술을 이용한 치조능 수평증대술: 증례보고", 구강회복응용과학지, 27(1), pp.109~115 (2011), 대한턱관절교합학회
  97. 김영균, "자가치아골이식재를 이용한 골유도재생술: 증례보고", 대한구강악안면외과학회지, 37(2), pp.142~147 (2011), 대한구강악안면외과학회
  98. 김영균, "자가치아골이식재를 이용한 치조능 수직 및 수평증대술: 증례보고", Maxillofacial Plastic Reconstructive Surgery, 33(2), pp.166~170 (2011), 대한악안면성형재건외과학회
  99. 이정훈, "자가치아를 이용한 골이식재의 임상적 유용성: 일차 보고", Maxillofacial Plastic Reconstructive Surgery, 33(2), pp.144~148 (2011), 대한악안면성형재건외과학회
  100. Jeong KI, "Clinical study of graft materials using autogenous teeth in maxillary sinus augmentation", Implant Dent, 20, pp.471~475 (2011)
  101. 정경인, "자가치아뼈이식재를 이용한 상악동증강술: 일차 보고", Maxillofacial Plastic Reconstructive Surgery, 33(3), pp.256~263 (2011), 대한악안면성형재건외과학회
  102. Sung-Min Park, "Clinical application of auto-tooth bone graft material", 대한구강악안면외과학회지, 38(1), pp.2~8 (2012), 대한구강악안면외과학회
  103. 이지영, "다양한 골이식재료를 이용한 상악동 골이식 4개월 후 조직형태계측학적 평가", 구강회복응용과학지, 27(2), pp.141~147 (2011), 대한턱관절교합학회
  104. 이지영, "자가치아 골이식술의 후향적 관찰연구", 구강생물학연구, 36(1), pp.39~43 (2012), 구강생물학연구소

관련 논문AI추천

이 간행물의 다른 논문 (7건)