Quality of life following surgical treatment of oral cancers
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Objectives: Quality of life (QoL) studies provide information about the impact of disease, the treatment of symptoms, and outcomes following treat-ment. The present study aims to evaluate the postoperative QoL of patients treated for oral cancer in a Nigerian government tertiary hospital. Materials and Methods: A prospective study on consenting patients with oral cancer was undertaken at Aminu Kano Teaching Hospital, Kano, Ni-geria. The subjects completed the University of Washington QoL (UW-QoL) questionnaire one day prior to surgery and postoperatively after 7 days, 1 month, 3 months, and 6 months. Results: Sixty-eight patients with oral cancer were recruited. Of these, 38 were males, and 30 were females (male : female, 1.3 : 1). Twenty-four pa-tients (12 males and 12 females) underwent surgery and completed postoperative QoL assessment using the UW-QoL questionnaire. Preoperative QoL mean score was 2.21, while postoperative mean scores after 1 week, 1 month, 3 months, and 6 months were 3.67, 3.46, 2.82, and 2.61, respectively. Conclusion: An improvement in QoL following surgical treatment for patients with oral cancer was observed. ‘Appearance,’ ‘recreation,’ and ‘chewing’ were identified as the most important determinants of postoperaive QoL in patients with oral cancer in our study.
Abstract
Objectives: Quality of life (QoL) studies provide information about the impact of disease, the treatment of symptoms, and outcomes following treat-ment. The present study aims to evaluate the postoperative QoL of patients treated for oral cancer in a Nigerian government tertiary hospital. Materials and Methods: A prospective study on consenting patients with oral cancer was undertaken at Aminu Kano Teaching Hospital, Kano, Ni-geria. The subjects completed the University of Washington QoL (UW-QoL) questionnaire one day prior to surgery and postoperatively after 7 days, 1 month, 3 months, and 6 months. Results: Sixty-eight patients with oral cancer were recruited. Of these, 38 were males, and 30 were females (male : female, 1.3 : 1). Twenty-four pa-tients (12 males and 12 females) underwent surgery and completed postoperative QoL assessment using the UW-QoL questionnaire. Preoperative QoL mean score was 2.21, while postoperative mean scores after 1 week, 1 month, 3 months, and 6 months were 3.67, 3.46, 2.82, and 2.61, respectively. Conclusion: An improvement in QoL following surgical treatment for patients with oral cancer was observed. ‘Appearance,’ ‘recreation,’ and ‘chewing’ were identified as the most important determinants of postoperaive QoL in patients with oral cancer in our study.
참고문헌 (21)
- Marx RE, "Oral and maxillofacial pathology: a rationale for diagnosis and treatment", pp.283~293 (2003), Quintessence Publishing
- Tang XH, "Oral cavity and esophageal carcinogenesis modeled in carcinogen-treated mice", Clin Cancer Res, 10, pp.301~313 (2004)
- Hotary K, "Regulation of cell invasion and morphogenesis in a three-dimensional type I collagen matrix by membrane-type matrix metalloproteinases 1, 2, and 3", J Cell Biol, 149, pp.1309~1323 (2000)
- Kaplan RN, "Preparing the "soil": the premetastatic niche", Cancer Res, 66, pp.11089~11093 (2006)
- Carnelio S, "Oral cancer at a glance", Internet J Dent Sci, 1(2) (2003)
- "SEER cancer statistics review, 1975-2005"[URL]
- World Health Organization, "International statistical classification of diseases and related health problems", pp.42~57 (1992), WHO
- Parkin DM, "Estimates of the worldwide incidence of eighteen major cancers in 1985", Int J Cancer, 54, pp.594~606 (1993)
- "The Oral Cancer Foundation"[URL]
- Levi F, "Worldwide patterns of cancer mortality, 1985-89", Eur J Cancer Prev, 3, pp.109~143 (1994)
- Rogers SN, "Importance-rating using the University of Washington quality of life questionnaire in patients treated by primary surgery for oral and oro-pharyngeal cancer", J Craniomaxillofac Surg, 30, pp.125~132 (2002)
- Goldspiel BR, "Human gene therapy", Clin Pharm, 12, pp.488~505 (1993)
- Arotiba GT, "Malignant orofacial neoplasms in Lagos, Nigeria", East Afr Med J, 83, pp.62~68 (2006)
- Ajayi OF, "Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital", Int J Oral Maxillofac Surg, 36, pp.403~408 (2007)
- Adekeye EO, "Intraoral carcinoma in Nigeria:a review of 137 cases", Ann R Coll Surg Engl, 67, pp.180~182 (1985)
- Ugboko V, "Primary orofacial squamous cell carcinoma: a multicenter Nigerian study", Internet J Dent Sci, 1(2) (2003)
- Arotiba JT, "Oral squamous cell carcinoma: a review of 246 Nigerian cases", Afr J Med Med Sci, 28, pp.141~144 (1999)
- Lippman SM, "Oral cancer prevention and the evolution of molecular-targeted drug development", J Clin Oncol, 23, pp.346~356 (2005)
- Kanatas AN, "A national survey of health-related quality of life questionnaires in head and neck oncology", Ann R Coll Surg Engl, 86, pp.6~10 (2004)
- Rogers SN, "A structured review and theme analysis of papers published on 'quality of life' in head and neck cancer: 2000-2005", Oral Oncol, 43, pp.843~868 (2007)
- Atchison KA, "Using patient self-report data to evaluate orofacial surgical outcomes", Community Dent Oral Epidemiol, 34, pp.93~102 (2006)
