A novel amnion-chorion allograft membrane combined with a coronally advanced flap: a minimally invasive surgical therapy to regenerate interdental papillary soft tissue recession – a six-month postoperative image analysis-based clinical trial
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Objectives: Loss of the interdental papilla is multi-factorial and creates a multitude of problems. Autogenous connective tissue/biomaterial-based regen-eration has been attempted for decades to reconstitute the black space created due to the loss of papilla. The aim of this present study was to regenerate papillary recession defects using an amnion-chorion membrane (ACM) allograft and to evaluate the clinical outcome up to six months postoperatively. Materials and Methods: Twenty patients with 25 Nordland and Tarnow’s Class I/II interdental papillary recession defects were treated with ACM and coronal advancement of the gingivo-papillary unit via a semilunar incision on the labial aspect followed by a sulcular incision in the area of inter-est. A photographic image analysis was carried out using the GNU Image Manipulation software program from the baseline to three and six months postoperatively. The black triangle height (BTH) and the black triangle width (BTW) were calculated using the pixel size and were then converted into millimeters. The mean and standard deviation values were determined at baseline and then again at three and six months postoperatively. The prob-ability values (P˂0.05 and P≤0.01) were considered statistically significant and highly significant, respectively. An analysis of variance and post hoc Bonferroni test were carried out to compare the mean values. Results: Our evaluation of the BTH and BTW showed a statistically and highly significant difference from the baseline until both three and six months postoperatively (P=0.01). A post hoc Bonferroni test disclosed a statistically significant variance from the baseline until three and six months postoperatively (P˂0.05) and a non-significant difference from three to six months after the procedure (P≥0.05). Conclusion: An ACM allograft in conjunction with a coronally advanced flap could be a suitable minimally invasive alternative for papillary regeneration.
Abstract
Objectives: Loss of the interdental papilla is multi-factorial and creates a multitude of problems. Autogenous connective tissue/biomaterial-based regen-eration has been attempted for decades to reconstitute the black space created due to the loss of papilla. The aim of this present study was to regenerate papillary recession defects using an amnion-chorion membrane (ACM) allograft and to evaluate the clinical outcome up to six months postoperatively. Materials and Methods: Twenty patients with 25 Nordland and Tarnow’s Class I/II interdental papillary recession defects were treated with ACM and coronal advancement of the gingivo-papillary unit via a semilunar incision on the labial aspect followed by a sulcular incision in the area of inter-est. A photographic image analysis was carried out using the GNU Image Manipulation software program from the baseline to three and six months postoperatively. The black triangle height (BTH) and the black triangle width (BTW) were calculated using the pixel size and were then converted into millimeters. The mean and standard deviation values were determined at baseline and then again at three and six months postoperatively. The prob-ability values (P˂0.05 and P≤0.01) were considered statistically significant and highly significant, respectively. An analysis of variance and post hoc Bonferroni test were carried out to compare the mean values. Results: Our evaluation of the BTH and BTW showed a statistically and highly significant difference from the baseline until both three and six months postoperatively (P=0.01). A post hoc Bonferroni test disclosed a statistically significant variance from the baseline until three and six months postoperatively (P˂0.05) and a non-significant difference from three to six months after the procedure (P≥0.05). Conclusion: An ACM allograft in conjunction with a coronally advanced flap could be a suitable minimally invasive alternative for papillary regeneration.
참고문헌 (30)
- Singh VP, "Black triangle dilemma and its management in esthetic dentistry", Dent Res J(Isfahan), 10, pp.296~301 (2013)
- Shenoy BS, "Salvaging the lost pink triangle: a case series of papilla reconstruction", Case Rep Dent, 2020, pp.9735074~ (2020)[DOI]
- Pitale U, "Minimally invasive therapy for reconstruction of lost interdental papilla by using injectable hyaluronic acid filler", J Indian Soc Periodontol, 25, pp.22~28 (2021)[DOI]
- Beagle JR, "Surgical reconstruction of the interdental papilla : case report", Int J Periodontics Restorative Dent, 12, pp.145~151 (1992)
- Azzi R, "Surgical thickening of the existing gingiva and reconstruction of interdental papillae around implant", Int J periodontol Rest Dent, 22, pp.71~77 (2002)
- Kaushik A, "Clinical evaluation of papilla reconstruction using subepithelial connective tissue graft", J Clin Diagn Res, 8, pp.ZC77~ZC81 (2014)[DOI]
- Azzi R, "Root coverage and papilla reconstruction using autogenous osseous and connective tissue grafts", Int J Periodontics Restorative Dent, 21, pp.141~147 (2001)
- Carranza N, "Reconstruction of the interdental papilla with an underlying subepithelial connective tissue graft: technical considerations and case reports", Int J Periodontics Restorative Dent., 31, pp.e45~e50 (2011)
- Federico Ausenda, "New Perspectives in the Use of Biomaterials for Periodontal Regeneration", Materials, 12(13), pp.2197~ (2019), MDPI AG[DOI]
- Geurs NC, "Efficacy of micronized acellular dermal graft for use in interproximal papillae regeneration", Int J Periodontics Restorative Dent, 32, pp.49~58 (2012)
- Gupta A, "Amnion and chorion membranes in the treatment of gingival recession and their effect on gingival biotype: a clinical and ultrasonographic study", J Clin Diagn Res, 12, pp.ZC26~ZC32 (2018)[DOI]
- Chakraborthy S, "Amnion and chorion allografts in combination with coronally advanced flap in the treatment of gingival recession: a clinical study", J Clin Diagn Res, 9, pp.ZC98~ZC101 (2015)[DOI]
- W. Peter Nordland, "A Classification System for Loss of Papillary Height", Journal of Periodontology, 69(10), pp.1124~1126 (1998), Wiley[DOI]
- THOMAS J. HAN, "Progress in gingival papilla reconstruction", Periodontology 2000, 11(1), pp.65~68 (1996), Wiley[DOI]
- Surajit Bhattacharya, "Clinical photography and our responsibilities", Indian Journal of Plastic Surgery, 47(03), pp.277~280 (2019), Georg Thieme Verlag KG[DOI]
- Corey H. Holmes, "Morphology of the Interdental Papillae", Journal of Periodontology, 36(6), pp.455~460 (1965), Wiley[DOI]
- Cohen B, "Pathology of the interdental tissues", Dent Pract, 9, pp.167~173 (1959)
- Hubert E. Schroeder, "The gingival tissues: the architecture of periodontal protection", Periodontology 2000, 13(1), pp.91~120 (1997), Wiley[DOI]
- G. Bourne, "The F tal Membranes: A Review of the Anatomy of Normal Amnion and Chorion and Some Aspects of Their Function", Postgraduate Medical Journal, 38(438), pp.193~201 (1962), BMJ[DOI]
- Thomas J Koob, "Biological properties of dehydrated human amnion", chorion composite graft: implications for chronic wound healing, 2013, pp.10(5), 493~500[DOI]
- Jennifer Lei, "Dehydrated Human Amnion", Chorion Membrane (dHACM) Allografts as a Therapy for Orthopedic Tissue Repair, 2017, pp.32(3), 149~157[DOI]
- Zeshaan N. Maan, "Cell recruitment by amnion chorion grafts promotes neovascularization", Journal of Surgical Research, 193(2), pp.953~962 (2015), Elsevier BV[DOI]
- Martin Grueterich, "Human Limbal Progenitor Cells Expanded on Intact Amniotic Membrane Ex Vivo", Archives of Ophthalmology, 120(6), pp.783~ (2002), American Medical Association (AMA)[DOI]
- N. Kjaergaard, "Antibacterial properties of human amnion and chorion in vitro", European Journal of Obstetrics & Gynecology and Reproductive Biology, 94(2), pp.224~229 (2001), Elsevier BV[DOI]
- Gurinsky B, "A novel dehydrated amnion allograft for use in the treatment of gingival recession : an observational case series", J Implant Adv Clin Dent, 1, pp.65~73 (2009)
- D.K. Suresh, "Gingival Biotype Enhancement and Root Coverage Using Human Placental Chorion Membrane", Clinical Advances in Periodontics, 3(4), pp.237~242 (2013), Wiley[DOI]
- Joshi CP, "Comparative evaluation of amnion-chorion membrane and chorion membrane for root coverage and gingival biotype enhancement : a case report", EC Dent Sci, 14, pp.255~259 (2017)
- Elzanaty M, "Clinical evaluation of amnion chorion membrane in comparison to subepithelial connective tissue graft in gingival recession coverage", Egypt Dent J., 30 (2017)
- Stella M. Pollard, "SCANNING ELECTRON MICROSCOPE APPEARANCES OF NORMAL HUMAN AMNION AND UMBILICAL CORD AT TERM", BJOG: An International Journal of Obstetrics and Gynaecology, 83(6), pp.470~477 (1976), Wiley[DOI]
- Sarah J. Stock, "Natural antimicrobial production by the amnion", American Journal of Obstetrics and Gynecology, 196(3), pp.255.e1~255.e6 (2007), Elsevier BV[DOI]