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체외 배양한 골수줄기세포를 이용한 말초신경재생에 관한 연구

A study of the effect of cultured bone marrow stromal cells on peripheral nerve regeneration

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참고문헌

주제분류치의학

초록

Abstract

The role of cultured bone marrow stromal cells (BMSCs) in peripheral nerve regeneration was examined using an established rabbit peroneal nerve regeneration model. A 15-mm peroneal nerve defect was bridged with a vein filled with BMSCs (1 × 106), which had been embedded in collagen gel. On the contralateral side, the defect was bridged with a vein filled with collagen gel alone. When the regenerated tissue was examined 4, 8 and 12 weeks after grafting, the number and diameter of the myelinated fibers in the side with the BMSCs were significantly higher than in the control side without the BMSCs. This demonstrates the potential of using cultured BMSCs in peripheral nerve regeneration.

참고문헌 (19)

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관련 논문AI추천

인간 골수 기질세포 이종이식이 백서의 축삭절단 안와하 신경 재생에 미치는 효과김은석, 김진만, 김현옥, 박은진, 염광원대한구강악안면외과학회 · 대한구강악안면외과학회지2005 · 제31권 제3호삼차원 배양된 슈반세포 도관을 이용한 말초 신경 재생김성민, 이종호대한구강악안면외과학회 · 대한구강악안면외과학회지2004 · 제30권 제1호비관형 천연 셀룰로오스막 도관을 이용한 말초신경 재생에 대한 실험적 연구김성민, 이석근, 이종호대한구강악안면외과학회 · 대한구강악안면외과학회지2006 · 제32권 제4호BMSC 이식과 장기간의 걷기 운동이 말초신경 손상 쥐의 랑비에결절 형성 단백질에 미치는 영향김영표, 서태범, 조영현학교체육연구소 · Asian Journal of Physical Education and Sport Science2023 · 제11권 제6호인회석 박막 피복 도관과 Brain-derived neurotrophic factor(BDNF) 유전자 이입 슈반세포를 이용한 백서 좌골신경 재생에 관한 연구김남열, 김명진, 김성민, 김성준, 김윤희, 김중수, 김현만, 안강민, 양병은, 오승재, 유상배, 이종호, 장정원, 정필훈, 최원재, 황순정대한구강악안면외과학회 · 대한구강악안면외과학회지2005 · 제31권 제3호BDNF 유전자 이입 슈반세포와 PGA 도관을 이용한 백서 좌골신경 재생에 관한 연구고은봉, 김남열, 김명진, 김병수, 김성민, 김윤태, 김윤희, 신영민, 안강민, 이종호, 장정원, 조승우, 최원재, 황순정대한구강악안면외과학회 · 대한구강악안면외과학회지2004 · 제30권 제6호

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