하악에 발생한 저등급의 점액섬유육종: 증례보고
Low-grade myxofibrosarcoma in the mandible: a case report
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Myxofibrosarcoma, also known as a myxoid variant of a malignant fibrous histiocytoma (MFH), is one of the most common sarcomas in the extremities of elderly people. The lesion is characterized by a high frequency of local recurrence but is uncommon in the head and neck regions. Low-grade myxofibrosarcoma, which is commonly misinterpreted as being benign, has a tendency for histological and biological progression in local recurrences, highlighting the importance of an accurate diagnosis and wide surgical excision of the primary lesion. We report a rare case of low-grade myxofibrosarcoma of the mandible located in the left mandibular body and angle area. The tumor was first diagnosed as a myxofibroma and was resected initially. After the final biopsy the patient underwent combined chemo-radiotherapy. The progress of the patent was uneventful until the one year follow up.
Abstract
Myxofibrosarcoma, also known as a myxoid variant of a malignant fibrous histiocytoma (MFH), is one of the most common sarcomas in the extremities of elderly people. The lesion is characterized by a high frequency of local recurrence but is uncommon in the head and neck regions. Low-grade myxofibrosarcoma, which is commonly misinterpreted as being benign, has a tendency for histological and biological progression in local recurrences, highlighting the importance of an accurate diagnosis and wide surgical excision of the primary lesion. We report a rare case of low-grade myxofibrosarcoma of the mandible located in the left mandibular body and angle area. The tumor was first diagnosed as a myxofibroma and was resected initially. After the final biopsy the patient underwent combined chemo-radiotherapy. The progress of the patent was uneventful until the one year follow up.
참고문헌 (15)
- Gugatschka M, "First case of a myxofibrosarcoma of the vocal folds: case report and review of the literature", J Voice, 24, pp.374~376 (2010)
- Nishimura G, "Myxofibrosarcoma of the hypopharynx", Auris Nasus Larynx, 33, pp.93~96 (2006)
- Wada T, "Myxofibrosarcoma with an infiltrative growth pattern: a case report", Jpn J Clin Oncol, 30, pp.458~462 (2000)
- Huang HY, "Lowgrade myxofibrosarcoma: a clinicopathologic analysis of 49 cases treated at a single institution with simultaneous assessment of the efficacy of 3-tier and 4-tier grading systems", Hum Pathol, 35, pp.612~621 (2004)
- Angervall L, "Myxofibrosarcoma. A study of 30 cases", Acta Pathol Microbiol Scand A, 85A, pp.127~140 (1977)
- Mentzel T, "Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant", Am J Surg Pathol, 20, pp.391~405 (1996)
- Sturgis EM, "Sarcomas of the head and neck region", Curr Opin Oncol, 15, pp.239~252 (2003)
- Nascimento AF, "Epithelioid variant of myxofibrosarcoma: expanding the clinicomorphologic spectrum of myxofibrosarcoma in a series of 17 cases", Am J Surg Pathol, 31, pp.99~105 (2007)
- Kummoona R, "Central myxofibrosarcoma of the mandible treated by radical resection", Oral Surg Oral Med Oral Pathol, 39, pp.713~717 (1975)
- Lam PK, "Myxofibrosarcoma of the sphenoid sinus", J Laryngol Otol, 116, pp.464~466 (2002)
- Pomerantz JM, "Myxofibrosarcoma of the maxillary sinus", Del Med J, 54, pp.147~152 (1982)
- Weiss SW, "Myxoid variant of malignant fibrous histiocytoma", Cancer, 39, pp.1672~1685 (1977)
- Soper CP, "Cervical myxofibrosarcoma in a renal allograft recipient treated with murine anti-CD3 monoclonal antibody therapy", Nephrol Dial Transplant, 13, pp.1902~1903 (1998)
- Merck C, "Myxofibrosarcoma. A malignant soft tissue tumor of fibroblastic-histiocytic origin. A clinicopathologic and prognostic study of 110 cases using multivariate analysis", Acta Pathol Microbiol Immunol Scand Suppl, 282, pp.1~40 (1983)
- Kearney MM, "Malifnant fibrous histiocytoma: a retrospective study of 167 cases", Cancer, 45, pp.167~178 (1980)