교근에서 기원한 고등급 근섬유육종 1예
A Case of High-Grade Myofibrosarcoma Originating From Masseter Muscle
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Myofibrosarcoma is a rare malignant tumor originating from myofibroblasts. It is classified into low-grade, intermediate-grade, and high-grade according to the histological characteris- tics. High-grade myofibrosarcoma is reported very rarely worldwide, and its recurrence and metastasis are known to be more common. Myofibrosarcoma is diagnosed by histopathologic examination, and its treatment is complete surgical excision. With a review of literature, we report a case of myofibrosarcoma originating from the right masseter muscle in a 73-year-old male patient who complained of a right chin mass for 4 months. The MRI findings revealed a 4.8 cm-sized heterogeneous contrast-enhancing mass in the right masseter muscle with direct invasion into the ipsilateral medial pterygoid muscle and the mandible body. The patient was treated with margin-free surgical excision, including marginal mandibulectomy, and a high- grade myofibrosarcoma was finally diagnosed as the pathologic finding. Adjuvant radiation therapy was performed as a subsequent treatment, and no recurrence has been observed dur- ing follow-up for 1 year.
Abstract
Myofibrosarcoma is a rare malignant tumor originating from myofibroblasts. It is classified into low-grade, intermediate-grade, and high-grade according to the histological characteris- tics. High-grade myofibrosarcoma is reported very rarely worldwide, and its recurrence and metastasis are known to be more common. Myofibrosarcoma is diagnosed by histopathologic examination, and its treatment is complete surgical excision. With a review of literature, we report a case of myofibrosarcoma originating from the right masseter muscle in a 73-year-old male patient who complained of a right chin mass for 4 months. The MRI findings revealed a 4.8 cm-sized heterogeneous contrast-enhancing mass in the right masseter muscle with direct invasion into the ipsilateral medial pterygoid muscle and the mandible body. The patient was treated with margin-free surgical excision, including marginal mandibulectomy, and a high- grade myofibrosarcoma was finally diagnosed as the pathologic finding. Adjuvant radiation therapy was performed as a subsequent treatment, and no recurrence has been observed dur- ing follow-up for 1 year.
참고문헌 (15)
- Galy-Bernadoy C, "Head and neck soft-tissue sarcoma in adults", Eur Ann Otorhinolaryngol Head Neck Dis, 133(1), pp.37~42 (2016)
- Tran LM, "Sarcomas of the head and neck. Prognostic factors and treatment strategies", Cancer, 70(1), pp.169~177 (1992)
- Fisher C, "Myofibrosarcoma", Virchows Arch, 445(3), pp.215~223 (2004)
- Fisher C, "Myofibroblastic malignancies", Adv Anat Pathol, 11(4), pp.190~201 (2004)
- Montgomery E, "Myofibrosarcoma : A clinicopathologic study", Am J Surg Pathol, 25(2), pp.219~228 (2001)
- Cai C, "In myofibroblastic sarcomas of the head and neck, mitotic activity and necrosis define grade: A case study and literature review", Virchows Arch, 463(6), pp.827~836 (2013)
- Montgomery E, "Myofibroblastic differentiation in malignant fibrous histiocytoma(pleomorphic myofibrosarcoma) : A clinicopathological study", Histopathology, 38(6), pp.499~509 (2001)
- Smith DM, "Myofibrosarcoma of the Head and Neck in Children", Pediatr Pathol Lab Med, 15(3), pp.403~418 (1995)
- Bisceglia M, "Myofibrosarcoma of the upper jawbones : A clinicopathologic and ultrastructural study of two cases", Ultrastruct Pathol, 25(5), pp.385~397 (2001)
- Kourelis K, "Mandibular myofibrosarcoma of childhood : Surgical resection & reconstruction with fibula flap", Braz J Otorhinolaryngol, 77(3), pp.404~ (2011)
- de Albuquerque Jr RLC, "High-grade myofibroblastic sarcoma of the mandible : Case report in a child and literature review", Oral Surg, 8(2), pp.91~95 (2015)
- Gonzalez FA, "Pleomorphic myofibrosarcoma of the tibia with aneuploid DNA content", Ann Diagn Pathol, 11(5), pp.340~344 (2007)
- Watanabe K, "Fibronexus in"malignant fibrous histiocytoma"of the bone : A case report of pleomorphic myofibrosarcoma", Ultrastruct Pathol, 26(1), pp.47~51 (2002)
- Hoos A, "High Ki-67 proliferative index predicts disease specific survival in patients with high-risk soft tissue sarcomas", Cancer, 92(4), pp.869~874 (2001)
- Politi M, "Review of segmental and marginal resection of the mandible in patients with oral cancer", Acta Otolaryngol, 120(5), pp.569~579 (2000)