수술 후 경정맥 영양공급과 일시적인 경구영양법을 받은 환자에서 발생한 베르니케 뇌병증 1예-증례 보고-
A Case of Wernicke’s Encephalopathy in a Postoperative Patient with Parenteral Nutrition and Temporary Oral Feeding-A Case Report-
2
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Wernicke’s encephalopathy is an acute neurological disorder, caused by thiamine deficiency, which is clinically characterized by a triad of ophthalmoplegia, ataxia and disturbances of consciousness. Most frequently, the encephalopathy is a consequence of chronic alcoholism, but it may occur in other forms of malnutrition or malabsorption,such as in prolonged parenteral nutrition without the addition of thiamine, total gastrectomy, gastrojejunostomy, severe anorexia or hyperemesis gravidarum. Thiamine requirement increases during critical illness and in chronically depleted patients, and its supplementation may influence the outcome of the disease. We report a case of a 73-year-old man, who presented with recurred colon cancer, who was affected by Wernicke’s encephalopathy while undergoing oral feeding and parenteral nutrition. This case suggests that we should be more aware of potential thiamine deficiency in critically ill patients, even those undergoing parenteral nutrition and temporary oral feeding.
Abstract
Wernicke’s encephalopathy is an acute neurological disorder, caused by thiamine deficiency, which is clinically characterized by a triad of ophthalmoplegia, ataxia and disturbances of consciousness. Most frequently, the encephalopathy is a consequence of chronic alcoholism, but it may occur in other forms of malnutrition or malabsorption,such as in prolonged parenteral nutrition without the addition of thiamine, total gastrectomy, gastrojejunostomy, severe anorexia or hyperemesis gravidarum. Thiamine requirement increases during critical illness and in chronically depleted patients, and its supplementation may influence the outcome of the disease. We report a case of a 73-year-old man, who presented with recurred colon cancer, who was affected by Wernicke’s encephalopathy while undergoing oral feeding and parenteral nutrition. This case suggests that we should be more aware of potential thiamine deficiency in critically ill patients, even those undergoing parenteral nutrition and temporary oral feeding.
참고문헌 (18)
- Dempsey DT, "The link between nutritional status and clinical outcome: can nutritional intervention modify it?", Am J Clin Nutr, 47(2 Suppl), pp.352~356 (1988)
- Parkin AJ, "Wernicke- Korsakoff syndrome of nonalcoholic origin", Brain Cogn, 15, pp.69~82 (1991)
- Francini-Pesenti F, "Wernicke's encephalopathy during parenteral nutrition", JPEN J Parenter Enteral Nutr, 31, pp.69~71 (2007)
- Hahn JS, "Wernicke encephalopathy and beriberi during total parenteral nutrition attributable to multivitamin infusion shortage", Pediatrics, 101, pp.E10~ (1998)
- 김소미, "흡인성 폐렴 환자에서 발생한 베르니케 뇌병증 1예", 대한중환자의학회지, 23(2), pp.106~110 (2008), 대한중환자의학회
- Torvik A, "Brain lesions in alcoholics. A neuropathological study with clinical correlations", J Neurol Sci, 56, pp.233~248 (1982)
- Darnton-Hill I, "Thiamin status of a sample of homeless clinic attenders in Sydney", Med J Aust, 152, pp.5~9 (1990)
- Cirignotta F, "Wernicke-korsakoff encephalopathy and polyneuropathy after gastroplasty for morbid obesity: report of a case", Arch Neurol, 57, pp.1356~1359 (2000)
- Thomson AD, "The natural history and pathophysiology of Wernicke's Encephalopathy and Korsakoff's psychosis", Alcohol Alcohol, 41, pp.151~158 (2006)
- Pagnan L, "Magnetic resonance imaging in a case of Wernicke's encephalopathy", Eur Radiol, 8, pp.977~980 (1998)
- Philip G, "Hypothermia and Wernicke's encephalopathy", Lancet, 2, pp.122~124 (1973)
- Truedsson M, "Wernicke's encephalopathy presenting with severe dysphagia: a case report", Alcohol Alcohol, 37, pp.295~296 (2002)
- 박우영, "췌십이지장절제술 후 발생한 지속적인 구토증과 Wernicke 뇌병증", 신경정신의학, 46(3), pp.267~270 (2007), 대한신경정신의학회
- Tucker ON, "Nutritional consequences of weight-loss surgery", Med Clin North Am, 91, pp.499~514 (2007)
- Attard O, "Wernicke encephalopathy: a complication of parenteral nutrition diagnosed by magnetic resonance imaging", Anesthesiology, 105, pp.847~848 (2006)
- Thomson AD, "Alcohol and brain damage", Hum Toxicol, 7, pp.455~463 (1988)
- Mancall EL, "Nutritional disorders of the nervous system. In: Neurology and general medicine. 2nd ed", pp.285~301 (1995), Churchill Livingstone
- Lenz V, "Value of MRI findings in Gayet-Wernicke encephalopathy", J Neuroradiol, 29, pp.153~160 (2002)
