티아민 보충 치료로 호전된 급성 어지럼: Wernicke Encephalopathy 1예
Acute Dizziness Treated With Thiamine Supplement: A Case of Wernicke Encephalopathy
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초록
Wernicke encephalopathy (WE) is an uncommon but severe neurological disorder caused bythiamine (vitamin B1) deficiency. It is characterized by the sudden onset of altered consciousness,ophthalmoplegia, and ataxia. Apart from chronic alcoholism, a lot of other conditionscausing malnutrition and decreasing thiamine absorption must be considered as predisposingfactors. Due to its low prevalence and clinical heterogeneity, WE is often misdiagnosed, resultingin persistent dysfunctions or death. Therefore, early diagnosis and prompt treatmentwith intravenous thiamine supplement might prevent encephalopathy and other neurologic orsystemic complications of thiamine depletion. We hereby report of our experience of a WEpatient who presented with predominantly vestibular symptoms and signs; the patient wassuccessfully diagnosed and treated with high-dose intravenous thiamine repletion.
Abstract
Wernicke encephalopathy (WE) is an uncommon but severe neurological disorder caused bythiamine (vitamin B1) deficiency. It is characterized by the sudden onset of altered consciousness,ophthalmoplegia, and ataxia. Apart from chronic alcoholism, a lot of other conditionscausing malnutrition and decreasing thiamine absorption must be considered as predisposingfactors. Due to its low prevalence and clinical heterogeneity, WE is often misdiagnosed, resultingin persistent dysfunctions or death. Therefore, early diagnosis and prompt treatmentwith intravenous thiamine supplement might prevent encephalopathy and other neurologic orsystemic complications of thiamine depletion. We hereby report of our experience of a WEpatient who presented with predominantly vestibular symptoms and signs; the patient wassuccessfully diagnosed and treated with high-dose intravenous thiamine repletion.
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