Clinical Application of Modified Burns Wean Assessment Program Scores at First Spontaneous Breathing Trial in Weaning Patients from Mechanical Ventilation
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Background: The purpose of this study was to evaluate the clinical application of modifiedBurns Wean Assessment Program (m-BWAP) scoring at first spontaneous breathing trial (SBT)as a predictor of successful liberation from mechanical ventilation (MV) in patients withendotracheal intubation. Methods: Patients requiring MV for more than 72 hours and undergoing more than one SBTin a medical intensive care unit (ICU) were prospectively enrolled over a 3-year period. Them-BWAP score at first SBT was obtained by a critical care nursing practitioner. Results: A total of 103 subjects were included in this study. Their median age was 69 years(range, 22 to 87 years) and 72 subjects (69.9%) were male. The median duration from admissionto first SBT was 5 days (range, 3 to 26 days), and the rate of final successful liberation fromMV was 84.5% (n=87). In the total group of patients, the successful liberation from MVgroup at first SBT (n=65) had significantly higher m-BWAP scores than did the unsuccessfulgroup (median, 60; range, 43 to 80 vs. median, 53; range, 33 to 70; P<0.001). Also, the areaunder the m-BWAP curve for predicting successful liberation of MV was 0.748 (95% confidenceinterval, 0.650 to 0.847), while the cutoff value based on Youden’s index was 53 (sensitivity,76%; specificity, 64%). Conclusions: The present data show that the m-BWAP score represents a good predictor ofweaning success in patients with an endotracheal tube in place at first SBT.
Abstract
Background: The purpose of this study was to evaluate the clinical application of modifiedBurns Wean Assessment Program (m-BWAP) scoring at first spontaneous breathing trial (SBT)as a predictor of successful liberation from mechanical ventilation (MV) in patients withendotracheal intubation. Methods: Patients requiring MV for more than 72 hours and undergoing more than one SBTin a medical intensive care unit (ICU) were prospectively enrolled over a 3-year period. Them-BWAP score at first SBT was obtained by a critical care nursing practitioner. Results: A total of 103 subjects were included in this study. Their median age was 69 years(range, 22 to 87 years) and 72 subjects (69.9%) were male. The median duration from admissionto first SBT was 5 days (range, 3 to 26 days), and the rate of final successful liberation fromMV was 84.5% (n=87). In the total group of patients, the successful liberation from MVgroup at first SBT (n=65) had significantly higher m-BWAP scores than did the unsuccessfulgroup (median, 60; range, 43 to 80 vs. median, 53; range, 33 to 70; P<0.001). Also, the areaunder the m-BWAP curve for predicting successful liberation of MV was 0.748 (95% confidenceinterval, 0.650 to 0.847), while the cutoff value based on Youden’s index was 53 (sensitivity,76%; specificity, 64%). Conclusions: The present data show that the m-BWAP score represents a good predictor ofweaning success in patients with an endotracheal tube in place at first SBT.
참고문헌 (26)
- Combes A, "Morbidity, mortality, and quality-of-life outcomes of patients requiring >or=14 days of mechanical ventilation", Crit Care Med, 31, pp.1373~1381 (2003)
- Douglas SL, "Survival and quality of life: short-term versus long-term ventilator patients", Crit Care Med, 30, pp.2655~2662 (2002)
- Epstein SK, "Extubation", Respir Care, 47, pp.483~492 (2002)
- Macintyre NR, "Evidence-based assessments in the ventilator discontinuation process", Respir Care, 57, pp.1611~1618 (2012)
- Vassilakopoulos T, "Respiratory muscles and weaning failure", Eur Respir J, 9, pp.2383~2400 (1996)
- McConville JF, "Weaning patients from the ventilator", N Engl J Med, 367, pp.2233~2239 (2012)
- Jiang JR, "Ultrasonographic evaluation of liver", spleen movements and extubation outcome, 2004, pp.126, 179~185
- Burns SM, "Design, testing, and results of an outcomes-managed approach to patients requiring prolonged mechanical ventilation", Am J Crit Care, 7, pp.45~57 (1998)
- Burns SM, "Implementation of an institutional program to improve clinical and financial outcomes of mechanically ventilated patients: one-year outcomes and lessons learned", Crit Care Med, 31, pp.2752~2763 (2003)
- Burns SM, "Multifactor clinical score and outcome of mechanical ventilation weaning trials: Burns Wean Assessment Program", Am J Crit Care, 19, pp.431~439 (2010)
- Burns SM, "The relationship of 26 clinical factors to weaning outcome", Am J Crit Care, 21, pp.52~58 (2012)
- Jiang JR, "Predicting weaning and extubation outcomes in long-term mechanically ventilated patients using the modified Burns Wean Assessment Program scores", Respirology, 19, pp.576~582 (2014)
- Roh JH, "A weaning protocol administered by critical care nurses for the weaning of patients from mechanical ventilation", J Crit Care, 27, pp.549~555 (2012)
- Tonnelier JM, "Impact of a nurses’ protocol-directed weaning procedure on outcomes in patients undergoing mechanical ventilation for longer than 48 hours: a prospective cohort study with a matched historical control group", Crit Care, 9, pp.R83~R89 (2005)
- Danckers M, "Nurse-driven, protocol-directed weaning from mechanical ventilation improves clinical outcomes and is well accepted by intensive care unit physicians", J Crit Care, 28, pp.433~441 (2013)
- Fagoni N, "Comparison between a nurse-led weaning protocol and weaning based on physician’s clinical judgment in tracheostomized critically ill patients: a pilot randomized controlled clinical trial", Ann Intensive Care, 8, pp.11~ (2018)
- Kim JH, "Influence of full-time intensivist and the nurse-to-patient ratio on the implementation of severe sepsis bundles in Korean intensive care units", J Crit Care, 27, pp.414~ (2012)
- 곽상현, "Current Status of Intensive Care Units Registered as Critical Care Subspecialty Training Hospitals in Korea", Journal of Korean Medical Science, 29(3), pp.431~437 (2014), 대한의학회
- Acute Respiratory Distress Syndrome Network, "Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome", N Engl J Med, 342, pp.1301~1308 (2000)
- MacIntyre NR, "The ventilator discontinuation process: an expanding evidence base", Respir Care, 58, pp.1074~1086 (2013)
- Haas CF, "Ventilator discontinuation protocols", Respir Care, 57, pp.1649~1662 (2012)
- Boles JM, "Weaning from mechanical ventilation", Eur Respir J, 29, pp.1033~1056 (2007)
- Charlson ME, "A new method of classifying prognostic comorbidity in longitudinal studies:development and validation", J Chronic Dis, 40, pp.373~383 (1987)
- Knaus WA, "APACHE II: a severity of disease classification system", Crit Care Med, 13, pp.818~829 (1985)
- Vincent JL, "The SOFA (Sepsis-related Organ Failure Assessment)score to describe organ dysfunction", failure. On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine, 1996, pp.22, 707~710
- Perkins NJ, "The inconsistency of “optimal”cutpoints obtained using two criteria based on the receiver operating characteristic curve", Am J Epidemiol, 163, pp.670~675 (2006)
