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Cone-beam computed tomographic comparison of chin symphysis bone particles and allograft versus iliac crest bone graft alone for reconstruction of alveolar bone defects in cleft patients

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Objectives: The aim of this study was to compare morbidities and duration of surgery, as well as bone formation in alveolar defects reconstructed with symphysis bone combined with allograft and iliac crest bone graft in patients with cleft palate. Patients and Methods: This randomized clinical trial was performed with 22 patients with unilateral alveolar cleft with a follow-up period of 12 months. In 12 patients, alveolar defects were reconstructed with chin bone graft plus allograft (Group A), while for the other 10 patients, iliac bone crest was used as donor site (Group B). Duration of surgery as well as occurrence of morbidities and complications were recorded. In addition, cone-beam computed tomographic (CBCT) scans were performed before surgery and 12 months after surgical procedures in order to compare bone forma-tion between the two groups. Results: Postoperative CBCT demonstrated a mean bone fill percentage of 76.9% of the alveolar defect in Group A, compared with 77.0% in Group B. Paresthesia in the lower lip or chin did not occur in any patients of Group A. The mean duration of the surgical process was significantly shorter for Group A (40 minutes vs 76 minutes, P<0.001). In addition, patients in Group A regained normal gait faster than patients in Group B (1 day vs 9.5 days). Conclusion: Mandibular symphysis bone graft in combination with allograft results in favorable outcomes in patients with unilateral alveolar clefts.

Abstract

Objectives: The aim of this study was to compare morbidities and duration of surgery, as well as bone formation in alveolar defects reconstructed with symphysis bone combined with allograft and iliac crest bone graft in patients with cleft palate. Patients and Methods: This randomized clinical trial was performed with 22 patients with unilateral alveolar cleft with a follow-up period of 12 months. In 12 patients, alveolar defects were reconstructed with chin bone graft plus allograft (Group A), while for the other 10 patients, iliac bone crest was used as donor site (Group B). Duration of surgery as well as occurrence of morbidities and complications were recorded. In addition, cone-beam computed tomographic (CBCT) scans were performed before surgery and 12 months after surgical procedures in order to compare bone forma-tion between the two groups. Results: Postoperative CBCT demonstrated a mean bone fill percentage of 76.9% of the alveolar defect in Group A, compared with 77.0% in Group B. Paresthesia in the lower lip or chin did not occur in any patients of Group A. The mean duration of the surgical process was significantly shorter for Group A (40 minutes vs 76 minutes, P<0.001). In addition, patients in Group A regained normal gait faster than patients in Group B (1 day vs 9.5 days). Conclusion: Mandibular symphysis bone graft in combination with allograft results in favorable outcomes in patients with unilateral alveolar clefts.

참고문헌 (42)

  1. Hupp JR, "Contemporary oral and maxillofacial surgery" (2013), Elsevier
  2. Vandeputte T, "Comparison between combined cortical and cancellous bone graft and cancellous bone graft in alveolar cleft : retrospective study of complications during the first six months post-surgery", J Craniomaxillofac Surg, 48, pp.38~42 (2020)[DOI]
  3. Itikala PR, "Maternal multivitamin use and orofacial clefts in offspring", Teratology, 63, pp.79~86 (2001)[DOI]
  4. Laron Z, "Pituitary growth hormone insufficiency associated with cleft lip and palate. An embryonal developmental defect", Helv Paediatr Acta, 24, pp.576~581 (1969)
  5. Loffredo LC, "Oral clefts and vitamin supplementation", Cleft Palate Craniofac J, 38, pp.76~83 (2001)[DOI]
  6. Little J, "Tobacco smoking and oral clefts : a meta-analysis", Bull World Health Organ, 82, pp.213~218 (2004)
  7. Stothard KJ, "Maternal overweight and obesity and the risk of congenital anomalies : a systematic review and meta-analysis", JAMA, 301, pp.636~650 (2009)[DOI]
  8. Jahanbin A, "Seasonal and yearly fluctuations in birth date of cleft lip and palate children in northern east of Iran, 1992–2007", Iran J Otorhinolaryngol, 20, pp.45~50 (2008)
  9. Eppley BL, "Management of alveolar cleft bone grafting--state of the art", Cleft Palate Craniofac J, 37, pp.229~233 (2000)[DOI]
  10. Morselli PG, "Treatment of alveolar cleft performing a pyramidal pocket and an autologous bone grafting", J Craniofac Surg, 20, pp.1566~1570 (2009)[DOI]
  11. Boyne PJ, "Autogenous cancellous bone and marrow transplants", Clin Orthop Relat Res, 73, pp.199~209 (1970)
  12. Wang LX, "Clinical study of cancellous iliac bone graft in cleft alveolar repair", Shanghai Kou Qiang Yi Xue, 17, pp.555~557 (2008)
  13. Besly W, "Technique for harvesting tibial cancellous bone modified for use in children", Br J Oral Maxillofac Surg, 37, pp.129~133 (1999)[DOI]
  14. Walker TW, "Retrospective review of donor site complications after harvest of cancellous bone from the anteriomedial tibia", Br J Oral Maxillofac Surg, 47, pp.20~22 (2009)[DOI]
  15. Kline RM Jr, "Complications associated with the harvesting of cranial bone grafts", Plast Reconstr Surg, 95, pp.5~13 (1995)
  16. van der Meij AJW, "Outcome of bone grafting in relation to cleft width in unilateral cleft lip and palate patients", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 96, pp.19~25 (2003)[DOI]
  17. Freihofer HP, "Timing and transplant materials for closure of alveolar clefts. A clinical comparison of 296 cases", J Craniomaxillofac Surg, 21, pp.143~148 (1993)[DOI]
  18. Sindet-Pedersen S, "Reconstruction of alveolar clefts with mandibular or iliac crest bone grafts : a comparative study", J Oral Maxillofac Surg, 48, pp.554~558 (1990)[DOI]
  19. Rahpeyma A, "Chin bone graft for maxillary alveolar cleft : indications and limitations", J Craniofac Surg, 25, pp.1650~1652 (2014)[DOI]
  20. Nwoku AL, "Retrospective analysis of secondary alveolar cleft grafts using iliac of chin bone", J Craniofac Surg, 16, pp.864~868 (2005)[DOI]
  21. Booij A, "Morbidity of chin bone transplants used for reconstructing alveolar defects in cleft patients", Cleft Palate Craniofac J, 42, pp.533~538 (2005)[DOI]
  22. Verdugo F, "Quantitation of mandibular symphysis volume as a source of bone grafting", Clin Implant Dent Relat Res, 12, pp.99~104 (2010)[DOI]
  23. Mahardawi Basel, "Alveolar cleft bone grafting: factors affecting case prognosis", 대한구강악안면외과학회지, 46(6), pp.409~416 (2020), 대한구강악안면외과학회[DOI]
  24. Elbokle N, "Volumetric assessment of mandibular symphyseal bone graft for secondary reconstruction of unilateral alveolar clefts", Egypt Dent J, 64, pp.2081~2088 (2018)[DOI]
  25. Movahedian Attar B, "Chin symphysis bone, allograft, and platelet-rich fibrin: is the combination effective in repair of alveolar cleft?", J Oral Maxillofac Surg, 75, pp.1026~1035 (2017)[DOI]
  26. Liang F, "3D cone beam computed tomography volumetric outcomes of rhBMP-2", demineralized bone matrix vs. Iliac crest bone graft for alveolar cleft reconstruction, 2015, pp.136(4S), 3~4
  27. Neovius E, "Alveolar bone healing accompanied by severe swelling in cleft children treated with bone morphogenetic protein-2 delivered by hydrogel", J Plast Reconstr Aesthet Surg, 66, pp.37~42 (2013)[DOI]
  28. MyeroffC, "Autogenous bone graft : donor sites and techniques", J Bone Joint Surg Am, 93, pp.2227~2236 (2011)[DOI]
  29. Francis CS, "rhBMP-2 with a demineralized bone matrix scaffold versus autologous iliac crest bone graft for alveolar cleft reconstruction", Plast Reconstr Surg, 131, pp.1107~1115 (2013)[DOI]
  30. Kamal M, "Volumetric comparison of autogenous bone and tissueengineered bone replacement materials in alveolar cleft repair : a systematic review and meta-analysis", Br J Oral Maxillofac Surg, 56, pp.453~462 (2018)[DOI]
  31. Thuaksuban N, "A comparison of autogenous bone graft combined with deproteinized bovine bone and autogenous bone graft alone for treatment of alveolar cleft", Int J Oral Maxillofac Surg, 39, pp.1175~1180 (2010)[DOI]
  32. Weijs WL, "Early secondary closure of alveolar clefts with mandibular symphyseal bone grafts and beta-tri calcium phosphate(beta-TCP)", Int J Oral Maxillofac Surg, 39, pp.424~429 (2010)[DOI]
  33. Miyagawa K, "Comparative evaluation of bone microstructure in alveolar cleft repair by cone beam CT : influence of different autologous donor sites and additional application of β-tricalcium phosphate", Clin Oral Investig, 24, pp.2789~2797 (2020)[DOI]
  34. Shirzadeh A, "A prospective study of chin bone graft harvesting for unilateral maxillary alveolar cleft during mixed dentition", J Oral Maxillofac Surg, 76, pp.180~188 (2018)[DOI]
  35. Hunt DR, "Autogenous bone harvesting : a chin graft technique for particulate and monocortical bone blocks", Int J Periodontics Restorative Dent, 19, pp.165~173 (1999)
  36. MacIsaac ZM, "Alveolar reconstruction in cleft patients : decreased morbidity and improved outcomes with supplemental demineralized bone matrix and cancellous allograft", Plast Reconstr Surg, 130, pp.625~632 (2012)[DOI]
  37. Abramowicz S, "Anterior versus posterior approach to iliac crest for alveolar cleft bone grafting", J Oral Maxillofac Surg, 70, pp.211~215 (2012)[DOI]
  38. Bukhari SGA, "Alveolar bone grafting with mandibular symphysis as donor material", Pak Oral Dent J, 29, pp.3~8 (2009)
  39. Laskin DM, "Accuracy of predicting the duration of a surgical operation", J Oral Maxillofac Surg, 71, pp.446~447 (2013)[DOI]
  40. Swan MC, "Morbidity at the iliac crest donor site following bone grafting of the cleft alveolus", Br J Oral Maxillofac Surg, 44, pp.129~133 (2006)[DOI]
  41. Rawashdeh MA, "Morbidity of iliac crest donor site following open bone harvesting in cleft lip and palate patients", Int J Oral Maxillofac Surg, 37, pp.223~227 (2008)[DOI]
  42. Albuquerque MA, "Comparison between multislice and cone-beam computerized tomography in the volumetric assessment of cleft palate", Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 112, pp.249~257 (2011)[DOI]

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