Association of nutrition risk screening 2002 and Malnutrition Universal Screening Tool with COVID-19 severity in hospitalized patients in Iran
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Background: Malnutrition affects normal body function and is associated with disease severity and mortality. Due to the high prevalence of malnutrition reported in patients with coronavirus disease 2019 (COVID-19), the current study examined the association between malnutrition and disease severity in hospitalized adult patients with COVID-19 in Iran.Methods: In this prospective observational study, 203 adult patients with COVID-19 verified by real-time polymerase chain reaction test and chest computed tomography were recruited from those admitted to a university hospital in Iran. To determine COVID-19 intensity, patients were categorized into four groups. Malnutrition assessment was based on the Malnutrition Universal Screening Tool (MUST) and nutrition risk screening score (NRS-2002). An ordinal regression model was run to assess the association between malnutrition and disease severity.Results: In the studies sample of Iranian patients with COVID-19, 38.3% of patients had severe COVID-19. According to NRS-2002, 12.9% of patients were malnourished. Based on MUST, 2% of patients were at medium, and 13.4% of patients were at high risk of malnutrition. Malnutrition was associated with a higher odds of extremely severe COVID-19 according to NRS-2002 (odds ratio, 1.38; 95% confidence interval, 0.21–2.56; P=0.021).Conclusions: Malnutrition was not prevalent in the studies sample of Iranian patients with COVID-19; however, it was associated with a higher odds of extremely severe COVID-19.
Abstract
Background: Malnutrition affects normal body function and is associated with disease severity and mortality. Due to the high prevalence of malnutrition reported in patients with coronavirus disease 2019 (COVID-19), the current study examined the association between malnutrition and disease severity in hospitalized adult patients with COVID-19 in Iran.Methods: In this prospective observational study, 203 adult patients with COVID-19 verified by real-time polymerase chain reaction test and chest computed tomography were recruited from those admitted to a university hospital in Iran. To determine COVID-19 intensity, patients were categorized into four groups. Malnutrition assessment was based on the Malnutrition Universal Screening Tool (MUST) and nutrition risk screening score (NRS-2002). An ordinal regression model was run to assess the association between malnutrition and disease severity.Results: In the studies sample of Iranian patients with COVID-19, 38.3% of patients had severe COVID-19. According to NRS-2002, 12.9% of patients were malnourished. Based on MUST, 2% of patients were at medium, and 13.4% of patients were at high risk of malnutrition. Malnutrition was associated with a higher odds of extremely severe COVID-19 according to NRS-2002 (odds ratio, 1.38; 95% confidence interval, 0.21–2.56; P=0.021).Conclusions: Malnutrition was not prevalent in the studies sample of Iranian patients with COVID-19; however, it was associated with a higher odds of extremely severe COVID-19.
참고문헌 (32)
- Bourke CD, "Immune dysfunction as a cause and consequence of malnutrition", Trends Immunol, 37, pp.386~398 (2016)
- Holder H, "Malnutrition in the elderly : a public health concern", Br J Nurs, 29, pp.118~119 (2020)
- Paynter S, "Malnutrition : a risk factor for severe respiratory syncytial virus infection and hospitalization", Pediatr Infect Dis J, 33, pp.267~271 (2014)
- Short KR, "Back to the future : lessons learned from the 1918 influenza pandemic", Front Cell Infect Microbiol, 8, pp.343~ (2018)
- Papadimitriou-Olivgeris M, "Predictors of mortality of influenza virus infections in a Swiss hospital during four influenza seasons : role of quick sequential organ failure assessment", Eur J Intern Med, 74, pp.86~91 (2020)
- Wu D, "The SARS-CoV-2 outbreak : what we know", Int J Infect Dis, 94, pp.44~48 (2020)
- Bedock D, "Prevalence and severity of malnutrition in hospitalized COVID-19 patients", Clin Nutr ESPEN, 40, pp.214~219 (2020)
- Li T, "Prevalence of malnutrition and analysis of related factors in elderly patients with COVID-19 in Wuhan, China", Eur J Clin Nutr, 74, pp.871~875 (2020)
- Larrazabal RB Jr, "The prevalence of malnutrition and analysis of related factors among adult patients with the coronavirus disease 2019(COVID 19)in a tertiary government hospital : the MalnutriCoV study", Clin Nutr ESPEN, 42, pp.98~104 (2021)
- Jia H, "Pulmonary angiotensin-converting enzyme 2(ACE2)and inflammatory lung disease", Shock, 46, pp.239~248 (2016)
- Frazier WJ, "Immunoparalysis and adverse outcomes from critical illness", Pediatr Clin North Am, 55, pp.647~668 (2008)
- Schoeman D, "Leptin deficiency, caused by malnutrition, makes you susceptible to SARS-CoV-2 infection but could offer protection from severe COVID-19", mSphere, 6, pp.e00031-21~ (2021)
- "The ‘MUST’ explanatory booklet" (2011)[URL]
- Kondrup J, "Nutritional risk screening (NRS 2002): a new method based on an analysis of controlled clinical trials", Clin Nutr, 22, pp.321~336 (2003)
- Javid Mishamandani Z, "Nutritional status of patients hospitalized in the intensive care unit : a comprehensive report from Iranian hospitals, 2018", J Crit Care, 54, pp.151~158 (2019)
- He F, "Coronavirus disease 2019 : what we know?", J Med Virol, 92, pp.719~725 (2020)
- Patel C, "Can nutritional assessment tools predict response to nutritional therapy?", Curr Gastroenterol Rep, 18, pp.15~ (2016)
- Schuetz P, "Individualised nutritional support in medical inpatients at nutritional risk : a randomised clinical trial", Lancet, 393, pp.2312~2321 (2019)
- Shen Y, "Effect of preoperative nutritional risk screening and enteral nutrition support in accelerated recovery after resection for esophageal cancer", Nutr Cancer, 73, pp.596~601 (2021)
- Stratton RJ, "Malnutrition in hospital outpatients and inpatients : prevalence, concurrent validity and ease of use of the ‘malnutrition universal screening tool’(‘MUST’)for adults", Br J Nutr, 92, pp.799~808 (2004)
- Wu C, "Risk factors associated with acute respiratory distress syndrome and death in patients with coronavirus disease 2019 pneumonia in Wuhan, China", JAMA Intern Med, 180, pp.934~943 (2020)
- Liu W, "Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease", Chin Med J(Engl), 133, pp.1032~1038 (2020)
- Kurtz A, "Long-term effects of malnutrition on severity of COVID-19", Sci Rep, 11, pp.14974~ (2021)
- Quilliot D, "Impact of severe SARS-CoV-2 infection on nutritional status and subjective functional loss in a prospective cohort of COVID-19 survivors", BMJ Open, 11, pp.e048948~ (2021)
- Norman K, "Prognostic impact of disease-related malnutrition", Clin Nutr, 27, pp.5~15 (2008)
- Hudson L, "Malnutrition identified by Academy of Nutrition and Dietetics", American Society for Parenteral and Enteral Nutrition is associated with more 30-day readmissions, greater hospital mortality, and longer hospital stays : a retrospective analysis of nutrition assessment data in a major medical center, 2018, pp.42, 892~897
- Agarwal E, "Malnutrition and poor food intake are associated with prolonged hospital stay, frequent readmissions, and greater in-hospital mortality : results from the Nutrition Care Day Survey 2010", Clin Nutr, 32, pp.737~745 (2013)
- Fedele D, "Obesity, malnutrition, and trace element deficiency in the coronavirus disease(COVID-19)pandemic : an overview", Nutrition, 81, pp.111016~ (2021)
- Anker MS, "Weight loss, malnutrition, and cachexia in COVID-19 : facts and numbers", J Cachexia Sarcopenia Muscle, 12, pp.9~13 (2021)
- Reber E, "Nutritional risk screening and assessment", J Clin Med, 8, pp.1065~ (2019)
- Velasco C, "Comparison of four nutritional screening tools to detect nutritional risk in hospitalized patients : a multicentre study", Eur J Clin Nutr, 65, pp.269~274 (2011)
- Cederholm T, "GLIM criteria for the diagnosis of malnutrition : a consensus report from the global clinical nutrition community", J Cachexia Sarcopenia Muscle, 10, pp.207~217 (2019)