Oxygen therapy for sepsis and prevention of complications

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참고문헌 (167)

1. Rudd KE, "Global, regional, and national sepsis incidence and mortality, 1990-2017 : analysis for the Global Burden of Disease Study", Lancet, 395, pp.200~211 (2020)
2. Rhee C, "Prevalence, Underlying causes, and preventability of sepsis-associated mortality in US acute care hospitals", JAMA Netw Open, 2, pp.e187571~ (2019)
3. Byrne L, "Fluid resuscitation in human sepsis : time to rewrite history?", Ann Intensive Care, 7, pp.4~ (2017)
4. Bauer M, "Mortality in sepsis and septic shock in Europe, North America and Australia between 2009 and 2019 : results from a systematic review and meta-analysis", Crit Care, 24, pp.239~ (2020)
5. Schlapbach LJ, "World Sepsis Day : a global agenda to target a leading cause of morbidity and mortality", Am J Physiol Lung Cell Mol Physiol, 319, pp.L518~L522 (2020)
6. Gaieski DF, "Benchmarking the incidence and mortality of severe sepsis in the United States", Crit Care Med, 41, pp.1167~1174 (2013)
7. Klastrup V, "Site of infection and mortality in patients with severe sepsis or septic shock. A cohort study of patients admitted to a Danish general intensive care unit", Infect Dis (Lond), 48, pp.726~731 (2016)
8. Chou EH, "Incidence, trends, and outcomes of infection sites among hospitalizations of sepsis : a nationwide study", PLoS One, 15, pp.e0227752~ (2020)
9. Lever A, "Sepsis : definition, epidemiology, and diagnosis", BMJ, 335, pp.879~883 (2007)
10. Bewick T, "Pneumonia in the context of severe sepsis : a significant diagnostic problem", Eur Respir J, 32, pp.1417~1418 (2008)
11. Mayr FB, "Epidemiology of severe sepsis", Virulence, 5, pp.4~11 (2014)
12. Szabo BG, "Clinical and microbiological characteristics and outcomes of community-acquired sepsis among adults : a single center, 1-year retrospective observational cohort study from Hungary", BMC Infect Dis, 19, pp.584~ (2019)
13. Vendemiato AV, "Microbiological characteristics of sepsis in a University hospital", BMC Infect Dis, 15, pp.58~ (2015)
14. Singer M, "The third international consensus definitions for sepsis and septic shock(sepsis-3)", JAMA, 315, pp.801~810 (2016)
15. Cecconi M, "Sepsis and septic shock", Lancet, 392, pp.75~87 (2018)
16. Weiss SL, "Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children", Pediatr Crit Care Med, 21, pp.e52~e106 (2020)
17. Coopersmith CM, "Surviving sepsis campaign : research priorities for sepsis and septic shock", Intensive Care Med, 44, pp.1400~1426 (2018)
18. Levy MM, "The Surviving Sepsis Campaign Bundle : 2018 update", Intensive Care Med, 44, pp.925~928 (2018)
19. Young P, "Conservative oxygen therapy for mechanically ventilated adults with sepsis : a post hoc analysis of data from the intensive care unit randomized trial comparing two approaches to oxygen therapy(ICU-ROX)", Intensive Care Med, 46, pp.17~26 (2020)
20. Panditrao MM, "Optimizing oxygen delivery in sepsis : a review", Adesh Univ J Med Sci Res, 1(1), pp.8~15 (2019)
21. Heffner JE, "The story of oxygen", Respir Care, 58, pp.18~31 (2013)
22. Shultz SM, "George E Holtzapple(1862-1946)and oxygen therapy for lobar pneumonia : the first reported case(1887)and a review of the contemporary literature to 1899", J Med Biogr, 13, pp.201~206 (2005)
23. Ragaller M, "Acute lung injury and acute respiratory distress syndrome", J Emerg Trauma Shock, 3, pp.43~51 (2010)
24. Pham T, "Fifty years of research in ARDS. The epidemiology of acute respiratory distress syndrome. A 50th birthday review", Am J Respir Crit Care Med, 195, pp.860~870 (2017)
25. Taylor MD, "Sometimes more is not always better : ScvO2 monitoring in pediatric sepsis", Intensive Care Med, 46, pp.1264~1266 (2020)
26. Bouvier NM, "Animal models for influenza virus transmission studies : a historical perspective", CurrOpinVirol, 13, pp.101~108 (2015)
27. Guillon A, "Preclinical septic shock research : why we need an animal ICU", Ann Intensive Care, 9, pp.66~ (2019)
28. Bean AG, "Studying immunity to zoonotic diseases in the natural host : keeping it real", Nat Rev Immunol, 13, pp.851~861 (2013)
29. Zingarelli B, "Part I : minimum quality threshold in preclinical sepsis studies(MQTiPSS)for study design and humane modeling endpoints", Shock, 51, pp.10~22 (2019)
30. Thom SR, "Intermittent hyperbaric oxygen therapy for reduction of mortality in experimental polymicrobial sepsis", J Infect Dis, 154, pp.504~510 (1986)
31. Guven A, "Medical ozone therapy reduces oxidative stress and intestinal damage in an experimental model of necrotizing enterocolitis in neonatal rats", J Pediatr Surg, 44, pp.1730~1735 (2009)
32. Halbach JL, "Early hyperbaric oxygen therapy improves survival in a model of severe sepsis", Am J PhysiolRegulIntegr Comp Physiol, 317, pp.R160~R168 (2019)
33. Buras JA, "Hyperbaric oxygen protects from sepsis mortality via an interleukin-10-dependent mechanism", Crit Care Med, 34, pp.2624~2629 (2006)
34. Aksenov I, "New roles of hyperbaric oxygen in sepsis", Chest, 132, pp.557A~ (2007)
35. Bektas A, "Do late phase hyperbaric and normobaric oxygen therapies have effect on liver damage? An experimental sepsis model", Gen Med (Los Angel), 7, pp.324~ (2019)
36. Yamanel L, "Ozone therapy and hyperbaric oxygen treatment in lung injury in septic rats", Int J Med Sci, 8, pp.48~55 (2011)
37. Hedetoft M, "Hyperbaric oxygen treatment is associated with a decrease in cytokine levels in patients with necrotizing soft-tissue infection", Physiol Rep, 9, pp.e14757~ (2021)
38. Nikitopoulou TS, "The inspiring journey of hyperbaric oxygen therapy, from the controversy to the acceptance by the scientific community", Health Sci J, 9, pp.1~ (2015)
39. Knighton DR, "Oxygen as an antibiotic. A comparison of the effects of inspired oxygen concentration and antibiotic administration on in vivo bacterial clearance", Arch Surg, 121, pp.191~195 (1986)
40. Bærnthsen NF, "Treatment with 24 h-delayed normo-and hyperbaric oxygenation in severe sepsis induced by cecal ligation and puncture in rats", J Inflamm(Lond), 14, pp.27~ (2017)
41. Ozturk A, "Comparison of the effects of hyperbaric oxygen and normobaric oxygen on sepsis in rats", Arch Clin Exp Surg, 5, pp.7~12 (2016)
42. Zhang Z, "Quadratic function between arterial partial oxygen pressure and mortality risk in sepsis patients : an interaction with simplified acute physiology score", Sci Rep, 6, pp.35133~ (2016)
43. Calzia E, "Hyperoxia may be beneficial", Crit Care Med, 38(10 Suppl), pp.S559~S568 (2010)
44. Perner A, "Trials on oxygen supplementation in sepsis : better late than never", Intensive Care Med, 46, pp.116~118 (2020)
45. Muth CM, "Hyperbaric oxygen and sepsis : time to recognize", Intensive Care Med, 31, pp.1150~1152 (2005)
46. Imperatore F, "Hyperbaric oxygen therapy prevents vascular derangement during zymosan-induced multiple-organ-failure syndrome", Intensive Care Med, 30, pp.1175~1181 (2004)
47. Sakoda M, "A potential role of hyperbaric oxygen exposure through intestinal nuclear factor-kappaB", Crit Care Med, 32, pp.1722~1729 (2004)
48. Chang KY, "HO-1 mediates the effects of HBO pretreatment against sepsis", J Surg Res, 136, pp.143~153 (2006)
49. Bar-Or D, "Sepsis, oxidative stress, and hypoxia : are there clues to better treatment?", Redox Rep, 20, pp.193~197 (2015)
50. Chiumello D, "Severe hypoxemia : which strategy to choose", Crit Care, 20, pp.132~ (2016)
51. Rossi P, "Could hyperoxic ventilation impair oxygen delivery in septic patients?", Clin Physiol Funct Imaging, 27, pp.180~184 (2007)
52. Pope JV, "Multicenter study of central venous oxygen saturation(ScvO(2))as a predictor of mortality in patients with sepsis", Ann Emerg Med, 55, pp.40~46 (2010)
53. Dahl RM, "Variability in targeted arterial oxygenation levels in patients with severe sepsis or septic shock", Acta Anaesthesiol Scand, 59, pp.859~869 (2015)
54. Hedenstierna G, "Alveolar collapse and closure of airways : regular effects of anaesthesia", Clin Physiol Funct Imaging, 23, pp.123~129 (2003)
55. Stolmeijer R, "A systematic review of the effects of hyperoxia in acutely ill patients : should we aim for less?", Biomed Res Int, 2018, pp.7841295~ (2018)
56. Yumoto M, "Septic shock following hyperbaric oxygen therapy in a patient with ileus", Jpn Soc Intensiv Care Med, 11, pp.127~131 (2004)
57. Vincent JL, "Harmful effects of hyperoxia in postcardiac arrest, sepsis, traumatic brain injury, or stroke : the importance of individualized oxygen therapy in critically ill patients", Can Respir J, 2017, pp.2834956~ (2017)
58. Page D, "Emergency department hyperoxia is associated with increased mortality in mechanically ventilated patients : a cohort study", Crit Care, 22, pp.9~ (2018)
59. Ni YN, "The effect of hyperoxia on mortality in critically ill patients : a systematic review and meta analysis", BMC Pulm Med, 19, pp.53~ (2019)
60. Pannu SR, "Too much oxygen : hyperoxia and oxygen management in mechanically ventilated patients", Semin Respir Crit Care Med, 37, pp.16~22 (2016)
61. Damiani E, "Oxygen in the critically ill : friend or foe?", Curr Opin Anaesthesiol, 31, pp.129~135 (2018)
62. Martin DS, "Oxygen therapy in critical illness : precise control of arterial oxygenation and permissive hypoxemia", Crit Care Med, 41, pp.423~432 (2013)
63. Jouffroy R, "Prognosis value of partial arterial oxygen pressure in patients with septic shock subjected to pre-hospital invasive ventilation", Am J Emerg Med, 37, pp.56~60 (2019)
64. Polat G, "Sepsis and septic shock : current treatment strategies and new approaches", Eurasian J Med, 49, pp.53~58 (2017)
65. Garner WL, "The effects of hyperoxia during fulminant sepsis", Surgery, 105, pp.747~751 (1989)
66. Siemieniuk R, "Oxygen therapy for acutely ill medical patients : a clinical practice guideline", BMJ, 363, pp.k4169~ (2018)
67. Genga KR, "Update of sepsis in the intensive care unit", J Innate Immun, 9, pp.441~455 (2017)
68. Hafner S, "Hyperoxia in intensive care, emergency, and peri-operative medicine: Dr. Jekyll or Mr. Hyde? A 2015 update", Ann Intensive Care, 5, pp.42~ (2015)
69. Tuder RM, "Hyperoxia and apoptosis. Too much of a good thing?", Am J Respir Crit Care Med, 183, pp.964~965 (2011)
70. Rodgers JL, "Impact of hyperoxia on cardiac pathophysiology", J Cell Physiol, 234, pp.12595~12603 (2019)
71. Escobar SJ, "Adjuvant hyperbaric oxygen therapy(HBO2)for treatment of necrotizing fasciitis reduces mortality and amputation rate", Undersea Hyperb Med, 32, pp.437~443 (2005)
72. Kranke P, "Hyperbaric oxygen therapy for chronic wounds", Cochrane Database Syst Rev, 2015, pp.CD004123~ (2015)
73. Chang YH, "Hyperbaric oxygen therapy ameliorates the blood-retinal barrier breakdown in diabetic retinopathy", Clin Exp Ophthalmol, 34, pp.584~589 (2006)
74. Piantadosi CA, "Carbon monoxide poisoning", Undersea Hyperb Med, 31, pp.167~177 (2004)
75. Minasyan H, "Phagocytosis and oxycytosis : two arms of human innate immunity", Immunol Res, 66, pp.271~280 (2018)
76. Minasyan H, "Mechanisms and pathways for the clearance of bacteria from blood circulation in health and disease", Pathophysiology, 23, pp.61~66 (2016)
77. Minasyan H, "Sepsis and septic shock : Pathogenesis and treatment perspectives", J Crit Care, 40, pp.229~242 (2017)
78. Buico A, "Oxidative stress and total antioxidant capacity in human plasma", Redox Rep, 14, pp.125~131 (2009)
79. Minasyan H, "Sepsis : mechanisms of bacterial injury to the patient", Scand J Trauma Resusc Emerg Med, 27, pp.19~ (2019)
80. Krötz F, "Reactive oxygen species : players in the platelet game", Arterioscler Thromb Vasc Biol, 24, pp.1988~1996 (2004)
81. Yun SH, "Platelet activation : the mechanisms and potential biomarkers", Biomed Res Int, 2016, pp.9060143~ (2016)
82. Iuliano L, "Oxygen free radicals and platelet activation", Free Radic Biol Med, 22, pp.999~1006 (1997)
83. Qiao J, "Regulation of platelet activation and thrombus formation by reactive oxygen species", Redox Biol, 14, pp.126~130 (2018)
84. Wachowicz B, "Generation of reactive oxygen species in blood platelets", Platelets, 13, pp.175~182 (2002)
85. Sill JC, "Reactive oxygen species and human platelet GP IIb", IIIa receptor activation, 2007, pp.18, 613~619
86. Helms CC, "Mechanisms of hemolysis-associated platelet activation", J Thromb Haemost, 11, pp.2148~2154 (2013)
87. Davis RP, "Platelets and coagulation in infection", Clin Transl Immunology, 5, pp.e89~ (2016)
88. Gawaz M, "Platelet activation and interaction with leucocytes in patients with sepsis or multiple organ failure", Eur J Clin Invest, 25, pp.843~851 (1995)
89. Alhamdi Y, "Recent advances in pathophysiology of disseminated intravascular coagulation : the role of circulating histones and neutrophil extracellular traps", F1000Res, 6, pp.2143~ (2017)
90. Carrim N, "Thrombin-induced reactive oxygen species generation in platelets : a novel role for protease-activated receptor 4 and GPIbα", Redox Biol, 6, pp.640~647 (2015)
91. Kambas K, "The emerging role of neutrophils in thrombosis-the journey of TF through NETs", Front Immunol, 3, pp.385~ (2012)
92. Delabranche X, "Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy", Intensive Care Med, 39, pp.1695~1703 (2013)
93. Morrissey JH, "Polyphosphate : a link between platelets, coagulation and inflammation", Int J Hematol, 95, pp.346~352 (2012)
94. Arman M, "Amplification of bacteria-induced platelet activation is triggered by FcγRIIA, integrin αIIbβ3, and platelet factor 4", Blood, 123, pp.3166~3174 (2014)
95. Antoniak S, "The coagulation system in host defense", Res Pract ThrombHaemost, 2, pp.549~557 (2018)
96. Semeraro N, "Sepsis, thrombosis and organ dysfunction", Thromb Res, 129, pp.290~295 (2012)
97. Broaddus VC, "Murray and Nadel’s textbook of respiratory medicin" (2016), Elsevier Saunders
98. "Oxygen saturation" (2021)[URL]
99. Weibel ER, "The pathway for oxygen" (1984), Cambridge, Harvard University Press
100. "Oxygen transport" (2011)[URL]
101. Collins JA, "Relating oxygen partial pressure, saturation and content : the haemoglobin-oxygen dissociation curve", Breathe(Sheff), 11, pp.194~201 (2015)
102. Christmas KM, "Equations for O2 and CO2 solubilities in saline and plasma : combining temperature and density dependences", J Appl Physiol(1985), 122, pp.1313~1320 (2017)
103. Wojciechowski WV, "Respiratory care sciences: an integrated approach" (2014), Delmar Cengage Learning
104. Beachey W, "Respiratory care anatomy and physiology: Foundations for Clinical Practice" (2018), Elsevier
105. Biolo G, "Glutathione metabolism in sepsis", Crit Care Med, 35(9 Suppl), pp.S591~S595 (2007)
106. Kim JS, "Plasma glutathione reductase activity and prognosis of septic shock", J Surg Res, 200, pp.298~307 (2016)
107. Gamarra Y, "Pyroglutamic acidosis by glutathione regeneration blockage in critical patients with septic shock", Crit Care, 23, pp.162~ (2019)
108. Fläring U, "Yearbook of intensive care and emergency medicine", pp.444~453 (2008), Springer
109. Pravda J, "Metabolic theory of septic shock", World J Crit Care Med, 3, pp.45~54 (2014)
110. Madian AG, "Proteomic identification of carbonylated proteins and their oxidation sites", J Proteome Res, 9, pp.3766~3780 (2010)
111. Weber D, "Determination of protein carbonyls in plasma, cell extracts, tissue homogenates, isolated proteins : focus on sample preparation and derivatization conditions", Redox Biol, 5, pp.367~380 (2015)
112. Kuhn SO, "Vitamin C in sepsis", Curr Opin Anaesthesiol, 31, pp.55~60 (2018)
113. Carr AC, "Hypovitaminosis C and vitamin C deficiency in critically ill patients despite recommended enteral and parenteral intakes", Crit Care, 21, pp.300~ (2017)
114. Pakala R, "Currently available methods for platelet function analysis : advantages and disadvantages", Cardiovasc Revasc Med, 12, pp.312~322 (2011)
115. Layios N, "Sepsis prediction in critically ill patients by platelet activation markers on ICU admission : a prospective pilot study", Intensive Care Med Exp, 5, pp.32~ (2017)
116. Zhou L, "Platelet aggregation testing in platelet-rich plasma : description of procedures with the aim to develop standards in the field", Am J Clin Pathol, 123, pp.172~183 (2005)
117. Collet JP, "Platelet function testing and implications for clinical practice", J Cardiovasc Pharmacol Ther, 14, pp.157~169 (2009)
118. Paniccia R, "Platelet function tests : a comparative review", Vasc Health Risk Manag, 11, pp.133~148 (2015)
119. Darling CE, "Point-of-care assessment of platelet reactivity in the emergency department may facilitate rapid rule-out of acute coronary syndromes : a prospective cohort pilot feasibility study", BMJ Open, 4, pp.e003883~ (2014)
120. Fowler AA 3rd, "Phase I safety trial of intravenous ascorbic acid in patients with severe sepsis", J Transl Med, 12, pp.32~ (2014)
121. Zabet MH, "Effect of high-dose Ascorbic acid on vasopressor’s requirement in septic shock", J Res Pharm Pract, 5, pp.94~100 (2016)
122. Marik PE, "Hydrocortisone, vitamin C, and thiamine for the treatment of severe sepsis and septic shock : a retrospective before-after study", Chest, 151, pp.1229~1238 (2017)
123. Fowler AA 3rd, "Effect of vitamin C infusion on organ failure and biomarkers of inflammation and vascular injury in patients with sepsis and severe acute respiratory failure : the CITRIS-ALI randomized clinical trial", JAMA, 322, pp.1261~1270 (2019)
124. Kalil AC, "Lack of benefit of high-dose vitamin c, thiamine, and hydrocortisone combination for patients with sepsis", JAMA, 323, pp.419~420 (2020)
125. de Grooth HJ, "Vitamin C pharmacokinetics in critically ill patients : a randomized trial of four IV regimens", Chest, 153, pp.1368~1377 (2018)
126. Wang Y, "Effects of different ascorbic acid doses on the mortality of critically ill patients : a meta-analysis", Ann Intensive Care, 9, pp.58~ (2019)
127. Spoelstra-de Man A, "Adjuvant vitamin C for sepsis : mono or triple?", Crit Care, 23, pp.425~ (2019)
128. Kashiouris MG, "The emerging role of vitamin C as a treatment for sepsis", Nutrients, 12, pp.292~ (2020)
129. Ribeiro Nogueira C, "Serum concentrations of vitamin A and oxidative stress in critically ill patients with sepsis", Nutr Hosp, 24, pp.312~317 (2009)
130. Zhang X, "Vitamin A deficiency in critically ill children with sepsis", Crit Care, 23, pp.267~ (2019)
131. Cherukuri L, "Vitamin A treatment for severe sepsis in humans; a prospective randomized double blind placebo-controlled clinical trial", Clin Nutr ESPEN, 29, pp.49~51 (2019)
132. Hariri Ahari M, "Vitamin D and sepsis", Int Sch Res Notices, 1, pp.225~228 (2014)
133. Behera CK, "Is lower vitamin D level associated with increased risk of neonatal sepsis? a prospective cohort study", Indian J Pediatr, 87, pp.427~432 (2020)
134. Kempker JA, "Vitamin D and sepsis : an emerging relationship", Dermatoendocrinol, 4, pp.101~108 (2012)
135. Kempker JA, "Vitamin D and sepsis : from associations to causal connections", Inflamm Allergy Drug Targets, 12, pp.246~252 (2013)
136. Shojaei M, "The correlation between serum level of vitamin D and outcome of sepsis patients : a cross-sectional study", Arch Acad Emerg Med, 7, pp.e1~ (2019)
137. Amrein K, "Short-term effects of high-dose oral vitamin D3 in critically ill vitamin D deficient patients : a randomized, double-blind, placebo-controlled pilot study", Crit Care, 15, pp.R104~ (2011)
138. Minter BE, "Differential effects of MitoVitE, α-tocopherol and trolox on oxidative stress, mitochondrial function and inflammatory signalling pathways in endothelial cells cultured under conditions mimicking sepsis", Antioxidants(Basel), 9, pp.195~ (2020)
139. Yamakawa K, "Optimal timing and early intervention with anticoagulant therapy for sepsis-induced disseminated intravascular coagulation", Clin Appl Thromb Hemost, 25, pp.1076029619835055~ (2019)
140. Umemura Y, "Screening itself for disseminated intravascular coagulation may reduce mortality in sepsis : a nationwide multicenter registry in Japan", Thromb Res, 161, pp.60~66 (2018)
141. Laursen MA, "Platelet function in disseminated intravascular coagulation : a systematic review", Platelets, 29, pp.238~248 (2018)
142. Assinger A, "Platelets in sepsis : an update on experimental models and clinical data", Front Immunol, 10, pp.1687~ (2019)
143. Kudo D, "The treatment intensity of anticoagulant therapy for patients with sepsis-induced disseminated intravascular coagulation and outcomes : a multicenter cohort study", Clin Appl Thromb Hemost, 25, pp.1076029619839154~ (2019)
144. ill patients?, "Ann Intensive Care", 2017, 115~
145. Lösche W, "Do aspirin and other antiplatelet drugs reduce the mortality in critically ill patients?", Thrombosis, 2012, pp.720254~ (2012)
146. Winning J, "Antiplatelet drugs and outcome in mixed admissions to an intensive care unit", Crit Care Med, 38, pp.32~37 (2010)
147. Kelm DJ, "Predictors of disseminated intravascular coagulation in patients with septic shock", Int Sch Res Notices, pp.219048~ (2013)
148. Tsao CM, "Coagulation abnormalities in sepsis", Acta Anaesthesiol Taiwan, 53, pp.16~22 (2015)
149. Jennings LK, "Mechanisms of platelet activation : need for new strategies to protect against platelet-mediated atherothrombosis", ThrombHaemost, 102, pp.248~257 (2009)
150. Ouyang Y, "Effects of antiplatelet therapy on the mortality rate of patients with sepsis : a meta-analysis", J Crit Care, 50, pp.162~168 (2019)
151. Wang Y, "Platelet activation and antiplatelet therapy in sepsis : a narrative review", Thromb Res, 166, pp.28~36 (2018)
152. Senno SL, "Disseminated intravascular coagulopathy(DIC) : pathophysiology, laboratory diagnosis, and management", J Intensive Care Med, 15, pp.144~158 (2000)
153. Sossdorf M, "Benefit of low-dose aspirin and non-steroidal anti-inflammatory drugs in septic patients", Crit Care, 17, pp.402~ (2013)
154. Eisen DP, "Acetyl salicylic acid usage and mortality in critically ill patients with the systemic inflammatory response syndrome and sepsis", Crit Care Med, 40, pp.1761~1767 (2012)
155. Eisen DP, "Manifold beneficial effects of acetyl salicylic acid and nonsteroidal anti-inflammatory drugs on sepsis", Intensive Care Med, 38, pp.1249~1257 (2012)
156. Otto GP, "Effects of low-dose acetylsalicylic acid and atherosclerotic vascular diseases on the outcome in patients with severe sepsis or septic shock", Platelets, 24, pp.480~485 (2013)
157. Eisen DP, "Effect of aspirin on deaths associated with sepsis in healthy older people(ANTISEPSIS) : a randomised, double-blind, placebo-controlled primary prevention trial", Lancet Respir Med, 9, pp.186~195 (2021)
158. Evangelista V, "Clopidogrel inhibits platelet-leukocyte adhesion and platelet-dependent leukocyte activation", ThrombHaemost, 94, pp.568~577 (2005)
159. Winning J, "Anti-platelet drugs and outcome in severe infection : clinical impact and underlying mechanisms", Platelets, 20, pp.50~57 (2009)
160. Dobesh PP, "Ticagrelor : pharmacokinetics, pharmacodynamics, clinical efficacy, and safety", Pharmacotherapy, 34, pp.1077~1090 (2014)
161. Storey RF, "Lower mortality following pulmonary adverse events and sepsis with ticagrelor compared to clopidogrel in the PLATO study", Platelets, 25, pp.517~525 (2014)
162. Scully M, "How we manage haemostasis during sepsis", Br J Haematol, 185, pp.209~218 (2019)
163. Hirsh J, "Mechanism of action and pharmacology of unfractionated heparin", Arterioscler Thromb Vasc Biol, 21, pp.1094~1096 (2001)
164. Liu XL, "Low-dose heparin as treatment for early disseminated intravascular coagulation during sepsis : a prospective clinical study", Exp Ther Med, 7, pp.604~608 (2014)
165. Polderman KH, "Drug intervention trials in sepsis : divergent results", Lancet, 363, pp.1721~1723 (2004)
166. Iba T, "Sepsis-induced coagulopathy and disseminated intravascular coagulation", Anesthesiology, 132, pp.1238~1245 (2020)
167. Wang C, "Heparin therapy reduces 28-day mortality in adult severe sepsis patients : a systematic review and meta-analysis", Crit Care, 18, pp.563~ (2014)

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