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치료 경험이 없는 HIV 감염자에서의 항바이러스제 일차 내성 분석: 한국HIV/AIDS 코호트 연구

Primary Anti-retroviral Resistance in Treatment-naive HIV-infected Patients: A Korean HIV/AIDS Cohort Study

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초록

Primary anti-retroviral resistance is considered one of the major problems of HIV treatment. Contrary to reports from western countries, prior Korean studies have reported a relatively low primary resistance rate (less than 5%). Based on Korean HIV/AIDS cohort data, we estimated the primary resistance rate among treatment-nave HIV- infected patients. According to the results, the primary resistance rate was higher (8.8%) than reported previously in Korean studies. However, the major PI mutation was not found.

Abstract

Primary anti-retroviral resistance is considered one of the major problems of HIV treatment. Contrary to reports from western countries, prior Korean studies have reported a relatively low primary resistance rate (less than 5%). Based on Korean HIV/AIDS cohort data, we estimated the primary resistance rate among treatment-nave HIV- infected patients. According to the results, the primary resistance rate was higher (8.8%) than reported previously in Korean studies. However, the major PI mutation was not found.

참고문헌 (12)

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  9. 김서린, "치료력이 없는 HIV 감염환자에서 약제내성 빈도", 대한내과학회지, 73(3), pp.243~250 (2007), 대한내과학회
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관련 논문AI추천

치료력이 없는 HIV 감염환자에서 약제내성 빈도곽임수, 김서린, 김형회, 류은경, 박순미, 설영미, 안순철, 유학선, 윤연경, 이선희, 이수진, 조군제, 차동혁대한내과학회 · 대한내과학회지2007 · 제73권 제3호HIV-1 Drug Resistance Mutations and Their Clinical Implications in South Korea신수, 김남희, 노은연, 박재현, 박현웅, 방지환, 윤종현, 윤지원, 정기욱대한진단검사의학회 · Laboratory Medicine Online2022 · 제12권 제2호Resistance Trends of Antiretroviral Agents in People with Human Immunodeficiency Virus in Korea, 2012 - 2020박상원, 이은영, Bang Jihwan, Oh Sang-Min대한감염학회 · Infection and Chemotherapy2023 · 제55권 제3호Comparison of Characteristics and Survival between Prospective and Retrospective Korea Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome Cohort Studies기미경, 김상일, 김신우, 김준형, 송준영, 최보율, 최윤수, 최준용대한감염학회 · Infection and Chemotherapy2019 · 제51권 제4호한국인 HIV 감염자에서 항레트로바이러스 치료이행도와 바이러스학적 치료 실패의 상관관계김연아, 김준명, 김창오, 박윤선, 박윤수, 송영구, 신소연, 윤희정, 최준용대한감염학회 · Infection and Chemotherapy2005 · 제37권 제1호The 2015 Clinical Guidelines for the Diagnosis and Treatment of HIV/AIDS in HIV-Infected Koreans대한에이즈학회대한감염학회 · Infection and Chemotherapy2015 · 제47권 제3호

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