Viral Shedding and Environmental Cleaning in Middle East Respiratory Syndrome Coronavirus Infection
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Viral shedding lasted 31 and 19 days from symptom onset in two patients with east respiratory syndrome coronavirus (MERS-CoV) pneumonia, respectively. Environmental real-time RT-PCR was weakly positive for bed guardrail and monitors. Even after cleaning the monitors with 70% alcohol-based disinfectant, RT-PCR was still weakly positive, and converted to negative only after wiping with diluted sodium chlorite. Further studies are required to clarify the appropriate methods to clean environments during and after treatment of patients with MERS-CoV infection.
Abstract
Viral shedding lasted 31 and 19 days from symptom onset in two patients with east respiratory syndrome coronavirus (MERS-CoV) pneumonia, respectively. Environmental real-time RT-PCR was weakly positive for bed guardrail and monitors. Even after cleaning the monitors with 70% alcohol-based disinfectant, RT-PCR was still weakly positive, and converted to negative only after wiping with diluted sodium chlorite. Further studies are required to clarify the appropriate methods to clean environments during and after treatment of patients with MERS-CoV infection.
참고문헌 (9)
- Zumla A, "Middle East respiratory syndrome", Lancet, 386, pp.995~1007 (2015)
- Al-Abdallat MM, "Hospital-associated outbreak of Middle East respiratory syndrome coronavirus: a serologic, epidemiologic, and clinical description", Clin Infect Dis, 59, pp.1225~1233 (2014)
- Assiri A, "Hospital outbreak of Middle East respiratory syndrome coronavirus", N Engl J Med, 369, pp.407~416 (2013)
- 대한감염학회, "An Unexpected Outbreak of Middle East Respiratory Syndrome Coronavirus Infection in the Republic of Korea, 2015", Infection and Chemotherapy, 47(2), pp.120~122 (2015), 대한감염학회[DOI]
- van Doremalen N, "Stability of Middle East respiratory syndrome coronavirus (MERSCoV)under different environmental conditions", Euro Surveill, 18 (2013)
- Boone SA, "Significance of fomites in the spread of respiratory and enteric viral disease", Appl Environ Microbiol, 73, pp.1687~1696 (2007)
- Infection prevention and control of epidemic- and pandemic-prone acute respiratory infections in health care, "World Health Organization", WHO, ~ (2014)
- Wu J, "Imported case of MERS-CoV infection identified in China, May 2015: detection and lesson learned", Euro Surveill, 20, pp.21158~ (2015)
- de Sousa R, "MERS coronavirus:data gaps for laboratory preparedness", J Clin Virol, 59, pp.4~11 (2014)
