An Imported Case of Brucella melitensis Infection in South Korea
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Brucellosis is a zoonotic infection that is usually transmitted from cattle to humans through ingestion of animal milk, direct contact with animal parts, or inhalation of aerosolized particles. In Korea, brucellosis seem to be transmitted through close contact with blood, fetus, urine, and placenta of domestic cow that has been infected by Brucella abortus, or inhalation of B. arbortus while examining or slaughtering cow. Brucella melitensis infection is rare in Korea and there have been no reported cases of B. melitensis originating from other countries until now. This report details a case of complicated brucellosis with infective spondylitis in a 48-year-old male construction worker recently returned from Iraq. Infection with B. melitensis was confirmed using 16s rRNA sequencing and omp31 gene analysis. The patient was successfully treated using a combination of rifampin, doxycycline, and streptomycin, in accordance with WHO guidelines. This is the first reported case of complicated brucellosis with infective spondylitis in Korea caused by B. melitensis originating from Iraq.
Abstract
Brucellosis is a zoonotic infection that is usually transmitted from cattle to humans through ingestion of animal milk, direct contact with animal parts, or inhalation of aerosolized particles. In Korea, brucellosis seem to be transmitted through close contact with blood, fetus, urine, and placenta of domestic cow that has been infected by Brucella abortus, or inhalation of B. arbortus while examining or slaughtering cow. Brucella melitensis infection is rare in Korea and there have been no reported cases of B. melitensis originating from other countries until now. This report details a case of complicated brucellosis with infective spondylitis in a 48-year-old male construction worker recently returned from Iraq. Infection with B. melitensis was confirmed using 16s rRNA sequencing and omp31 gene analysis. The patient was successfully treated using a combination of rifampin, doxycycline, and streptomycin, in accordance with WHO guidelines. This is the first reported case of complicated brucellosis with infective spondylitis in Korea caused by B. melitensis originating from Iraq.
참고문헌 (15)
- Ryu SY, "Brucella prostatitis: a first case report diagnosed in Korea", Korean J Pathol, 45(Suppl 1), pp.S66~S69 (2011)[DOI]
- Pappas G, "Brucellosis", N Engl J Med, 352, pp.2325~2336 (2005)[DOI]
- Skalsky K, "Treatment of human brucellosis: systematic review and meta-analysis of randomised controlled trials", BMJ, 336, pp.701~704 (2008)[DOI]
- Colmenero JD, "Clinical findings, therapeutic approach, and outcome of brucellar vertebral osteomyelitis", Clin Infect Dis, 46, pp.426~433 (2008)[DOI]
- Lim HS, "Brucellosis: an overview", Korean J Epidemiol, 27, pp.26~36 (2005)
- Guerra H, "The brucellae and their success as pathogens", Crit Rev Microbiol, 33, pp.325~331 (2007)[DOI]
- Jang Y, "Epidemiological aspects of human brucellosis and leptospirosis outbreaks in Korea", J Clin Med Res, 3, pp.199~202 (2011)
- 김선형, "범혈구감소증을 보인 브루셀라증 환자에서 치료 후 발생한 급성골수성백혈병 1예", Laboratory Medicine Online, 5(3), pp.157~160 (2015), 대한진단검사의학회
- Ariza J, "Perspectives for the treatment of brucellosis in the 21st century: the Ioannina recommendations", PLoS Med, 4, pp.e317~ (2007)[DOI]
- Ablon G, "A Randomized, Double-blind, Placebo-controlled, Multi-center, Extension Trial Evaluating the Efficacy of a New Oral Supplement in Women with Self-perceived Thinning Hair", J Clin Aesthet Dermatol, 8, pp.15~21 (2015)
- Solis Garcia del Pozo J, "Systematic review and meta-analysis of randomized clinical trials in the treatment of human brucellosis", PLoS One, 7, pp.e32090~ (2012)[DOI]
- Hachung Yoon, "Epidemiology of brucellosis among cattle in Korea from 2001 to 2011", Journal of Veterinary Science, 15(4), pp.537~543 (2014), 대한수의학회[DOI]
- Rubach MP, "Brucellosis in low-income and middle-income countries", Curr Opin Infect Dis, 26, pp.404~412 (2013)[DOI]
- 박민석, "국내 브루셀라균에 감염된 환자 1예", Infection and Chemotherapy, 35(6), pp.461~466 (2003), 대한감염학회
- 김연숙, "국내에서 발생하고 있는 사람 브루셀라증의 임상적 특성", Infection and Chemotherapy, 38(6), pp.334~343 (2006), 대한감염학회