Importance of Culture for Diagnosing Human Brucellosis
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Human brucellosis is a newly emerging infectious disease in Korea, and the number of the patients with this disease has rapidly increased in recent years. To evaluate the most reliable method in diagnosing human brucellosis, a retrospective study was conducted. Medical records of patients admitted or followed-up at the outpatient department of a tertiary care university hospital during the past 5 years were reviewed. Among a total of 32 human brucellosis patients (24 males and 8 females),21 (65.6%) were positive for standard tube agglutination test (STA) but negative for blood or bone marrow culture, 7 (21.9%) were positive for both STA and culture,and 4 (12.5%) were STA negative but culture positive. Based on these findings, we recommend that physicians include blood and/or bone marrow culture to obtain definitive diagnosis when clinical symptoms and signs strongly suggest the human brucellosis, even when STA is negative.
Abstract
Human brucellosis is a newly emerging infectious disease in Korea, and the number of the patients with this disease has rapidly increased in recent years. To evaluate the most reliable method in diagnosing human brucellosis, a retrospective study was conducted. Medical records of patients admitted or followed-up at the outpatient department of a tertiary care university hospital during the past 5 years were reviewed. Among a total of 32 human brucellosis patients (24 males and 8 females),21 (65.6%) were positive for standard tube agglutination test (STA) but negative for blood or bone marrow culture, 7 (21.9%) were positive for both STA and culture,and 4 (12.5%) were STA negative but culture positive. Based on these findings, we recommend that physicians include blood and/or bone marrow culture to obtain definitive diagnosis when clinical symptoms and signs strongly suggest the human brucellosis, even when STA is negative.
참고문헌 (5)
- Corbel MJ, "Brucellosis: an overview", Emerg Infect Dis, 3, pp.213~221 (1997)
- Pappas G, "The new global map of human brucellosis", Lancet Infect Dis, 6, pp.91~99 (2006)
- Pappas G, "Brucellosis", N Engl J Med, 352, pp.2325~2336 (2005)
- Centers for Disease Control and Prevention, "Case definitions for infectious conditions under public health surveillance", MMWR Morb Mortal Wkly Rep, 46, pp.1~55 (1997)
- Memish Z, "Brucella bacteraemia: clinical and laboratory observations in 160 patients", J Infect, 40, pp.59~63 (2000)