Influenza Vaccines: Unmet Needs and Recent Developments
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Influenza is a worldwide public health concern. Since the introduction of trivalent influenza vaccine in 1978, vaccination hasbeen the primary means of prevention and control of influenza. Current influenza vaccines have moderate efficacy, good safety,and acceptable tolerability; however, they have unsatisfactory efficacy in older adults, are dependent on egg supply for production,and are time-consuming to manufacture. This review outlines the unmet medical needs of current influenza vaccines. Recentdevelopments in influenza vaccines are also described.
Abstract
Influenza is a worldwide public health concern. Since the introduction of trivalent influenza vaccine in 1978, vaccination hasbeen the primary means of prevention and control of influenza. Current influenza vaccines have moderate efficacy, good safety,and acceptable tolerability; however, they have unsatisfactory efficacy in older adults, are dependent on egg supply for production,and are time-consuming to manufacture. This review outlines the unmet medical needs of current influenza vaccines. Recentdevelopments in influenza vaccines are also described.
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