갑상선 기능 항진증을 동반한 쇼그렌 증후군 1례
A Case of Sjögren's Syndrome with Hyperthyroidism
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초록
쇼그렌 증후군은 대부분 중년여성에 발생하며 어린시기에 나타나는 경우가 드물고 갑상선 질환을 동반 하는 예는 흔치 않으며 특히 갑상선 기능 항진증을 동반하는 경우는 더욱 드물다. 이에 저자들은 좌측 이하선 종창을 주소로 내원한 10세 여아에서 갑상선 기능 항진증을 동반한 일차성 쇼그렌 증후군 1례를 경험하였기에 보고하는 바이다.
Abstract
Sjögren syndrome is a chronic, slowly progressive, autoimmune disease in which the exocrine glands are damaged by lymphocytic infiltration, resulting in xerostomia and xerophthalmia. Sjögren syndrome may occur in 2 forms: primary Sjögren syndrome, when the clinical manifestations of the syndrome are seen alone, and secondary Sjögren syndrome, when associated with another autoimmune disease, such as rheumatoid arthritis, systemic lupus erythromatosus, or scleroderma. Approximately one third of patients present with extraglandular manifestations: arthritis, Raynaud phenomenon, lymphadenopathy, lung involvement, vasculitis and peripheral nervous system involvement. About 10-50% of patients with Sjögren syndrome had evidence of thyroid disease, mainly hypothyroidism. Several inflammatory thyroid diseases are also considered to be autoimmune in origin. In this respect, the histologic picture of primary Sjögren syndrome exocrine glands and autoimmune thyroid glands show great similarities. Here, we report a new case of Sjögren syndrome accompanying with hyperthyroidism which affected a 10-year-old girl.
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