Endocrine and metabolic emergencies in children: hypocalcemia, hypoglycemia, adrenal insufficiency, and metabolic acidosis including diabetic ketoacidosis
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초록
It is important to fast diagnosis and management of the pediatric patients of the endocrine metabolic emergencies because the signs and symptoms of these disorders are nonspecific. Delayed diagnosis and treatment may lead to serious consequences of the pediatric patients, for example, cerebral dysfunction leading to coma or death of the patients with hypoglycemia, hypocalcemia, adrenal insufficiency, or diabetic ketoacidosis. The index of suspicion of the endocrine metabolic emergencies should be preceded prior to the starting nonspecific treatment. Importantly, proper diagnosis depends on the collection of blood and urine specimen before nonspecific therapy (intravenous hydration, electrolytes, glucose or calcium injection). At the same time, the taking of precise history and searching for pathognomonic physical findings should be performed. This review was described for fast diagnosis and proper management of hypoglycemic emergencies, hypocalcemia, adrenal insufficiency, and metabolic acidosis including diabetic ketoacidosis.
Abstract
Hypoglycemia, Hypocalcemia, Adrenal insufficiency, Metabolic acidosis, Diabetic ketoacidosis
참고문헌 (23)
- The Korean Society of Pediatric Endocrinology, "Pediatric endocrinology", pp.515~526 (2014), Koonja Co
- Lteif AN, "Hypoglycemia in infants and children", Endocrinol Metab Clin North Am, 28, pp.619~646 (1999)
- Cornblath M, "Controversies regarding definition of neonatal hypoglycemia: suggested operational thresholds", Pediatrics, 105, pp.1141~1145 (2000)
- Shaul PW, "The role of magnesium in neonatal calcium homeostasis: effects of magnesium infusion on calciotropic hormones and calcium", Pediatr Res, 22, pp.319~323 (1987)
- The Korean Society of Pediatric Endocrinology, "Pediatric endocrinology", pp.257~294 (2014), Koonja Co
- Misra M, "Vitamin D deficiency in children and its management: review of current knowledge and recommendations", Pediatrics, 122, pp.398~417 (2008)
- Shaw N., "A practical approach to hypocalcaemia in children", Endocr Dev, 16, pp.73~92 (2009)
- Song JY, "Clinical characteristics of symptomatic hypocalcemic infants", J Korean Soc Pediatr Endocrinol, 7, pp.95~104 (2002)
- Root AW, "Pediatric endocrinology", pp.686~769 (2008), Elsevier Saunders Co
- Bornstein SR., "Predisposing factors for adrenal insufficiency", N Engl J Med, 360, pp.2328~2339 (2009)
- The Korean Society of Pediatric Endocrinology, "Pediatric endocrinology", pp.325~357 (2014), Koonja Co
- Arlt W, "Adrenal insufficiency", Lancet, 361, pp.1881~1893 (2003)
- Miller WL, "Pediatric endocrinology", pp.444~511 (2008), Elsevier Saunders Co
- Speiser PW, "Congenital adrenal hyperplasia", N Engl J Med, 349, pp.776~788 (2003)
- Langer M, "Adrenal insufficiency in the critically ill neonate and child", Curr Opin Pediatr, 18, pp.448~453 (2006)
- Rothstein M, "Renal tubular acidosis", Endocrinol Metab Clin North Am, 19, pp.869~887 (1990)
- Lim S., "Metabolic acidosis", Acta Med Indones, 39, pp.145~150 (2007)
- Lorenz JM, "Serum anion gap in the differential diagnosis of metabolic acidosis in critically ill newborns", J Pediatr, 135, pp.751~755 (1999)
- The Korean Society of Pediatric Endocrinology, "Pediatric endocrinology", pp.607~615 (2014), Koonja Co
- Glaser N, "Risk factors for cerebral edema in children with diabetic ketoacidosis. The Pediatric Emergency Medicine Collaborative Research Committee of the American Academy of Pediatrics", N Engl J Med, 344, pp.264~269 (2001)
- Wolfsdorf J, "Diabetic ketoacidosis", Pediatr Diabetes, 8, pp.28~43 (2007)
- Wolfsdorf J, "Diabetic ketoacidosis in infants, children, and adolescents: A consensus statement from the American Diabetes Association", Diabetes Care, 29, pp.1150~1159 (2006)
- Resenbloom AL., "Therapeutic controversy: prevention and treatment of diabetes in children. Cerebral edema in diabetic ketoacidosis", J Clin Endocrinol Metab, 85, pp.507~508 (2000)
