16세 청소년에서 발생한 갑상샘중독 주기성 마비 1례
A Case of Thyrotoxic Periodic Paralysis in a 16-Year-Old Adolescent
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초록
갑상샘 중독성 주기성 마비는 갑상샘 항진증의 드문 합병증으로 소아청소년 연령에서는 발생 보고가 매우 드물다. 저자들은 그레이브스병으로 치료 중인 16세 남자 청소년에서 저칼륨혈증을 동반한 갑상샘 중독성 주기성 마비가 3회에걸쳐 재발한 증례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다.
Abstract
Thyrotoxic periodic paralysis (TPP) is a transient illness characterized by muscle weakness often associated with hypokalemia during thyrotoxic state. Hypokalemia is induced by thyroid hormone excess through stimulation of Na-K ATPase which pumps extracellular potassium ions into the cell. Muscle weakness resolves when serum potassium level is corrected, but the condition may recur when there is thyrotoxicosis. TPP is most commonly reported in Asian males aged between 20 to 40 years and it is rare in children and adolescents. We report a 16-year-old patient previously diagnosed with Graves’ disease who showed recurrent episodes of TPP.
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