만성 폐쇄성 폐질환 환자에서 신체활동과 고혈압 이환율 간의관련성
Association between Physical Activity and Hypertension in Chronic Obstructive Pulmonary Disease
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연구배경: 만성 폐쇄성 폐질환(COPD) 환자에서 고혈압의 높은 동반 이환을 보여주는 앞선 연구 및 조사결과들이보고되고 있으며 그로 인한 심혈관질환의 이환이 높아져사망률 또한 높아짐이 보고되고 있다. 이에 본 연구에서는COPD 환자군에 있어 신체활동 정도에 따른 고혈압 이환정도를 알아보고자 한다. 방법: 2010-2012년에 수행된 제5기 국민건강영양조사 자료를 이용하여 만 40세 이상의 성인 중 1,243명의 COPD 환자를 대상으로 교차분석 및 로지스틱 회귀분석을 실시하였으며, 신체활동의 정도에 따라 대상자를 분류하여 고혈압 동반 이환과의 관련성을 알아보았다. 결과: COPD 환자 중 고혈압이 없는 자에서 중등도 신체활동을 하는 자의 분율이 고혈압이 있는 자에서의 분율보다 4.3% 유의하게 높았다(P=0.012). COPD 환자에서 신체활동 정도와 고혈압 동반 이환의 위험도를 살펴보기 위해나이, 성별, 소득수준, 비만도, 흡연과 음주 여부, 당뇨, 고지혈증의 동반 이환, 에너지 섭취량 등을 고려하여 보았을때 중등도 운동을 시행하는 군에서 고혈압의 동반된 위험도가 0.536배(95% 신뢰구간, 0.288-0.997) 낮았다. 결론: COPD 환자군에서 신체활동 중 중등도의 신체활동을 하는 경우 고혈압의 이환 정도가 유의하게 낮음을 알수 있었다.
Abstract
Background: Patients with chronic obstructive pulmonary disease (COPD) have increased likelihood of hypertension, which may lead to increased mortality rates. This study investigated the incidence of hypertension in patients with COPD according to the levels of their physical activities. Methods: This study used data from the fifth Korean National Health and Nutrition Examination Survey, conducted from 2010 to 2012, including 1,243 people aged 40 years or older with COPD who were cross-classified according to their levels of physical activity. The relevance of morbidity associated with high blood pressure was also evaluated through cross and logistic regression analyses. Results: Among patients with COPD who performed moderate-intensity physical activities, the group without hypertension had 4.3% higher compared to the group with hypertension (P=0.012). Adjusted analysis for patient age, sex, body mass index, smoking, drinking habit, income, diabetes mellitus, hyperlipidemia, and energy intake performed to determine the relationship between physical activity level and hypertension revealed that patients with moderate-intensity physical activity had 53.6% lower (95% confidence interval: 0.288-0.997) incidence of hypertension. Conclusions: The results of the current study suggest that patients with COPD who perform moderate-intensity physical activity have a lower incidence of hypertension.
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