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한국 남성에서 CT로 평가한 복부지방의 측정 위치와 대사증후군과의 관련성

Association between the Measurement Location of Abdominal Fat Evaluated by CT and Metabolic Syndrome among Korean Men

박석건|최은영
대한임상건강증진학회 (Korean Society For Health Promotion And Disease Prevention)|2008.12|Korean Journal of Health Promotion|제8권 제4호|pp. 272-280

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대사증후군metabolic syndrome전산화단층촬영복부피하지방내장지방computed tomography측정 위치visceral adipose tissueabdominal subcutaneous adipose tissuemeasurement location
주제분류기타자연과학

초록

연구배경 :한국 남성에서 복부지방의 측정위치가 대사증후군과 복부지방의 관계에 미치는 영향을 파악하기 위해 시행되었다. 방 법 : 2006년 1월부터 2006년 8월까지 단국대학교병원을 내원하여 종합검진과 PET/CT를 시행한 성인 남성 55명을 대상으로 선정 하였다. 요추 4~5번을 중심으로 하방 5cm에서 상방 20cm까지 5cm 간격으로 피하지방과 내장지방의 면적을 측정하였다. 다중로짓회귀분석을 이용하여 연령을 보정한 상태에서 복부내장지방과 복부피하지방 면적이 1 표준편차씩 증가함에 따라 대사증후군이 될 교차비를 계산하였다. 결 과 : 대사증후군에 대한 내장지방 면적의 교차비는 요추 4~5번 상방 5cm에서 3.33(95% 신뢰구간:1.55-7.19, P=0.002)으로 요추 4~5번에서의 교차비 2.25(95% 신뢰구간:1.12-4.56, P=0.023)보다 컸다. 요추 4~5번 하방 5cm를 제외한 모든 위치에서 내장지방 면적은 대사증후군과 유의한 관련성을 보였으나(P<0.05), 측정 위치에 따른 교차비는 2.00‐3.33로 그 차이는 크지 않았다. 복부피하지방의 면적은 측정위치에 관계없이 대사증후군과 통계적으로 유의한 관련성은 없었다(P>0.05). 결 론 : 요추 4~5번 하방 5cm를 제외한 모든 위치에서 내장지방은 대사증후군과 유의한 관련성을 보였으며, 복부지방의 측정 위치에 관계없이 복부피하지방은 대사증후군과 관련이 없었다. 복부지방의 측정위치가 대사증후군과 복부지방의 관계에 미치는 영향은 크지 않았다.

Abstract

Background : This study was conducted to evaluate the influence of measurement location on the association between metabolic syndrome and abdominal fat evaluated by CT among Korean men Methods :The subjects consisted of 55 Korean men who underwent Positron Emission Tomography/Computed Tomography (PET/CT) as a part of general health checkup at Dankook University Hospital. VAT and ASAT were measured using CT data from PET/CT chosen at 5cm intervals between 5cm below and 20cm above L4~5 level. The odds ratio (OR) per SD increase in VAT and ASAT was calculated using multiple logistic regressions adjusted for age. Results : The OR for metabolic syndrome with VAT was highest for 5cm above L4~L5 (OR=3.33, 95% confidence interval: 1.55-7.19, P=0.002), greater than that for L4~5 level (OR=2.25, 95% confidence interval: 1.12-4.56, P=0.023). VAT was associated with metabolic syndrome in all measurement location except for 5cm below L4~5. The differences of odds ratio according to measurement location were not great. However, ASAT was not associated with metabolic syndrome regardless of measurement location (P>0.50). Conclusions : VAT was associated with metabolic syndrome in all measurement location except for 5cm below L4~5. ASAT was not associated with metabolic syndrome regardless of measurement location. Influence of measurement location was not great on the relationship between metabolic syndrome and abdominal fat.

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