한국 여성 직장인 및 직장인 배우자의 고위험군 인유두종 바이러스 유병률
Prevalence of High Risk Human Papillomavirus among the FemaleEmployees and Employees' Partner in Korea
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연구배경 : 한국 여성 직장인 및 직장인 배우자를 대상으로 인유두종 바이러스 유병률을 조사하고, 이를 한국 일반 인구로 표준화한 표준화 유병률을 제시하고자 하였다. 인유두종 바이러스 유병률과 자궁경부 세포진검사와의 연관을 함께 구명하였으며, 비교를 위해 개인비용 종합건강진단 수검자의 결과를 함께 제시하였다. 방 법 : 2007년 1월부터 2007년 12월까지 일개대학병원 종합건진센터를 방문하여 직장에서 지불해주는 비용으로 정기 종합건강진단을 받은 여성 직장인 및 직장인 배우자 16,937명을 연구대상으로 하였으며, Hybrid-Capture II assay(HC-II) 방법을 이용하여 인유두종 바이러스 양성유무를 판단하여 유병률을 조사하였다. 결 과 : 여성 직장인 및 배우자로 구성된 연구대상자 16,937명중 1,936명이 고위험도 인유두종 바이러스 양성을 나타내 11.4%의 유병률을 보였다. 2005년 한국 여성인구를 표준인구로 한 표준화 유병률은 9.49% 였다. 특히 20~29세군(15.3%)과 50~59세군(17.7%)이 다른 연령군에 비해 유병률이 높았다. 연령군간 인유두종 바이러스 유병률의 차이는 통계적으로 유의하였다(P-value<0.01). 여성 직장인 및 배우자의 인유두종 바이러스 양성과 자궁경부 세포진검사 유소견과의 교차비는 48.0(95% 신뢰구간 27.1-84.6)이었다. 결 론 : 한국 여성 직장인 및 배우자로 구성된 16,937명 여성의 고위험군 인유두종 바이러스 표준화 유병률은 9.49%이다.
Abstract
Background This study was conducted to evaluated the prevalence of human papillomavirus(HPV) among the female employees and employees' partner in Korea. And this study was conducted to evaluate relationship between HPV and cervical cytology. Methods HPV test of 16,937 study population conducted using Hybrid-Capture II assay(HC-II). The study population were people who visited hospital-based medical screening center from January to December 2007 and all were female employees or employees' partner. Results HPV positive subjects are 1,936 people among total 16,937 study population. Crude prevalence of HPV was 11.4%, and standardized prevalence was 9.49%. The prevalence of 20-29 age group and 50-59 age group were relatively high than other groups. HPV prevalence was significantly different between age groups. The odd ratio of HPV positve and cervical cytology positive was 48.0 (95% CI 27.1-84.6). Conclusions The standardized prevalence of high risk human papillomavirus was 9.49% among the female employees and employees' partner in Korea.
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