Herpes Zoster Reactivation in Patients with Coronary Artery Disease
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The association between varicella-zoster virus (VZV) reactivation and coronary artery disease (CAD) remains uncertain. We enrolled 107 patients (mean age 66.5±10.8 years; 72% male) who underwent coronary angiography due to suspected CAD and assessed subclinical VZV reactivation via salivary VZV PCR. Patients were divided into three groups: acute coronary syndrome, chronic coronary syndrome, and insignificant CAD. VZV DNA was detected in three patients (3%) —one in the acute group and two in the chronic group (P=0.469). Although not statistically significant, these findings warrant further investigation into the potential link between VZV reactivation and CAD.
Abstract
The association between varicella-zoster virus (VZV) reactivation and coronary artery disease (CAD) remains uncertain. We enrolled 107 patients (mean age 66.5±10.8 years; 72% male) who underwent coronary angiography due to suspected CAD and assessed subclinical VZV reactivation via salivary VZV PCR. Patients were divided into three groups: acute coronary syndrome, chronic coronary syndrome, and insignificant CAD. VZV DNA was detected in three patients (3%) —one in the acute group and two in the chronic group (P=0.469). Although not statistically significant, these findings warrant further investigation into the potential link between VZV reactivation and CAD.