Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds

키워드

참고문헌 (34)

1. Takahashi K, "Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors", Cell, 126, pp.663~676 (2006)
2. Thakurela S, "Differential regulation of OCT4 targets facilitates reacquisition of pluripotency", Nat. Commun, 10, pp.4444~ (2019)
3. Hussein SM, "Genome-wide characterization of the routes to pluripotency", Nature, 516, pp.198~206 (2014)
4. Li R, "A mesenchymal-to-epithelial transition initiates and is required for the nuclear reprogramming of mouse fibroblasts", Cell Stem Cell, 7, pp.51~63 (2010)
5. Zunder ER, "A continuous molecular roadmap to iPSC reprogramming through progression analysis of single-cell mass cytometry", Cell Stem Cell, 16, pp.323~337 (2015)
6. Jones PAJNRG, "Functions of DNA methylation : islands, start sites, gene bodies and beyond", Net. Rev. Genet, 13, pp.484~492 (2012)
7. Polo JM, "A molecular roadmap of reprogramming somatic cells into iPS cells", Cell, 151, pp.1617~1632 (2012)
8. Peinado H, "Transforming growth factor β-1 induces snail transcription factor in epithelial cell lines : mechanisms for epithelial mesenchymal transitions", J. Biol. Chem, 278, pp.21113~21123 (2003)
9. Feldman N, "G9a-mediated irreversible epigenetic inactivation of Oct-3", 4during early embryogenesis, 2006, pp.8, 188~194
10. Shi Y, "Induction of pluripotent stem cells from mouse embryonic fibroblasts by Oct4 and Klf4 with small-molecule compounds", Cell Stem Cell, 3, pp.568~574 (2008)
11. Huangfu D, "Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds", Nat. Biotechnol, 26, pp.795~797 (2008)
12. Ichida JK, "A small-molecule inhibitor of Tgf-β signaling replaces Sox2 in reprogramming by inducing Nanog", Cell Stem Cell, 5, pp.491~503 (2009)
13. Esteban MA, "Vitamin C enhances the generation of mouse and human induced pluripotent stem cells", Cell Stem Cell, 6, pp.71~79 (2010)
14. Cerella C, "Antagonistic role of natural compounds in mTOR-mediated metabolic reprogramming", Cancer Lett, 356, pp.251~262 (2015)
15. Furusawa J-i, "Glycyrrhiza inflata-derived chalcones, Licochalcone A, Licochalcone B and Licochalcone D, inhibit phosphorylation of NF-κB p65 in LPS signaling pathway", Int. Immunopharmacol, 9, pp.499~507 (2009)
16. Huber MA, "NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression", J. Clin. Inverst, 114, pp.569~581 (2004)
17. Zengtao Wang, "Short and Efficient Synthesis of Licochalcone B and D Through Acid-Mediated Claisen-Schmidt Condensation", Bulletin of the Korean Chemical Society, 34(12), pp.3906~3908 (2013), 대한화학회[DOI]
18. Choi HW, "Neural stem cells differentiated from iPS cells spontaneously regain pluripotency", Stem Cells, 32, pp.2596~2604 (2014)
19. Zhang L, "Small molecules efficiently reprogram human astroglial cells into functional neurons", Cell Stem Cell, 17, pp.735~747 (2015)
20. Zheng J, "A combination of small molecules directly reprograms mouse fibroblasts into neural stem cells", Biochem. Biophys. Res. Cpommun, 476, pp.42~48 (2016)
21. Liu D, "Small molecules for neural stem cell induction", Stem Cells Dev, 27, pp.297~312 (2018)
22. Grünert S, "Diverse cellular and molecular mechanisms contribute to epithelial plasticity and metastasis", Nat. Rev. Mol. Cell Biol, 4, pp.657~665 (2003)
23. Maherali N, "Tgfβ signal inhibition cooperates in the induction of iPSCs and replaces Sox2 and cMyc", Curr. Biol, 19, pp.1718~1723 (2009)
24. Thiery JP, "Epithelial-mesenchymal transitions in development and disease", Cell, 139, pp.871~890 (2009)
25. Thiery JP, "Epithelial–mesenchymal transitions in development and pathologies", Curr. Opin. Cell Biol, 15, pp.740~746 (2003)
26. Samavarchi-Tehrani P, "Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming", Cell Stem Cell, 7, pp.64~77 (2010)
27. Silva J, "Promotion of reprogramming to ground state pluripotency by signal inhibition", PLoS Biol, 6, pp.e253~ (2008)
28. "All natural", Nat. Chem. Biol, 3, pp.351~ (2007)
29. Atanasov AG, "Discovery and resupply of pharmacologically active plant-derived natural products : a review", Biotechnol. Adv, 33, pp.1582~1614 (2015)
30. Romashkova JA, "NF-κB is a target of AKT in anti-apoptotic PDGF signalling", Nature, 401, pp.86~90 (1999)
31. Kane LP, "Induction of NF-κB by the Akt", PKB kinase, 1999, pp.9, 601~604
32. Nidai Ozes O, "NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase", Nature, 401, pp.82~85 (1999)
33. Takeda K, "Limb and skin abnormalities in mice lacking IKKα", Science, 284, pp.313~316 (1999)
34. Cao Y, "IKKα provides an essential link between RANK signaling and cyclin D1 expression during mammary gland development", Cell, 107, pp.763~775 (2001)

관련 논문AI추천