Two Cases of Primary Ovarian Insufficiency Accompanied by High Serum Anti-Müllerian Hormone Levels and Preservation of Ovarian Follicles
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Primary ovarian insufficiency (POI) is defined as the presence of amenorrhea for ≥ 4 months accompanied by evidence of two serum follicle-stimulating hormone levels in the menopausal range in women aged < 40 years. Anti-Müllerian hormone (AMH) has been recognized as the most reliable marker of ovarian reserve status, and its serum level is very low or undetectable in women with POI. Here we report two cases of patients who were diagnosed with POI despite high serum AMH levels and preservation of ovarian follicles, as revealed by ultrasound. In addition, we have presented a review of the current literature regarding this condition.
Abstract
Primary ovarian insufficiency (POI) is defined as the presence of amenorrhea for ≥ 4 months accompanied by evidence of two serum follicle-stimulating hormone levels in the menopausal range in women aged < 40 years. Anti-Müllerian hormone (AMH) has been recognized as the most reliable marker of ovarian reserve status, and its serum level is very low or undetectable in women with POI. Here we report two cases of patients who were diagnosed with POI despite high serum AMH levels and preservation of ovarian follicles, as revealed by ultrasound. In addition, we have presented a review of the current literature regarding this condition.
참고문헌 (17)
- Taylor HS, "Speroff’s clinical gynecologic endocrinology and infertility", pp.343~394 (2019), Lippincott Williams & Wilkins
- Baker VL, "Berek &Novak’s gynecology", pp.866~888 (2019), Lippincott Williams & Wilkins
- La Marca A, "Serum anti-müllerian hormone levels in women with secondary amenorrhea", Fertil Steril, 85, pp.1547~1549 (2006)
- Vujovic S, "EMAS position statement : managing women with premature ovarian failure", Maturitas, 67, pp.91~93 (2010)
- Knauff EA, "Anti-Mullerian hormone, inhibin B, and antral follicle count in young women with ovarian failure", J Clin Endocrinol Metab, 94, pp.786~792 (2009)
- 이정렬, "여성 생식에서 Anti-Müllerian Hormone의 역할", Obstetrics & Gynecology Science, 52(3), pp.285~300 (2009), 대한산부인과학회
- Visser JA, "Anti-Müllerian hormone : an ovarian reserve marker in primary ovarian insufficiency", Nat Rev Endocrinol, 8, pp.331~341 (2012)
- Dewailly D, "Diagnosis of polycystic ovary syndrome(PCOS) : revisiting the threshold values of follicle count on ultrasound and of the serum AMH level for the definition of polycystic ovaries", Hum Reprod, 26, pp.3123~3129 (2011)
- Bakalov VK, "Autoimmune oophoritis as a mechanism of follicular dysfunction in women with 46, XX spontaneous premature ovarian failure", Fertil Steril, 84, pp.958~965 (2005)
- Kallio S, "Anti-Mullerian hormone as a predictor of follicular reserve in ovarian insufficiency : special emphasis on FSH-resistant ovaries", Hum Reprod, 27, pp.854~860 (2012)
- La Marca A, "Primary ovarian insufficiency due to steroidogenic cell autoimmunity is associated with a preserved pool of functioning follicles", J Clin Endocrinol Metab, 94, pp.3816~3823 (2009)
- Massin N, "Evaluation of different markers of the ovarian reserve in patients presenting with premature ovarian failure", Mol Cell Endocrinol, 282, pp.95~100 (2008)
- Komorowska B, "Autoimmune premature ovarian failure", Prz Menopauzalny, 15, pp.210~214 (2016)
- Jones GS, "A new syndrome of amenorrhae in association with hypergonadotropism and apparently normal ovarian follicular apparatus", Am J Obstet Gynecol, 104, pp.597~600 (1969)
- Li Y, "Successful live birth in a woman with resistant ovary syndrome following in vitro maturation of oocytes", J Ovarian Res, 9, pp.54~ (2016)
- Grynberg M, "First birth achieved after in vitro maturation of oocytes from a woman endowed with multiple antral follicles unresponsive to follicle-stimulating hormone", J Clin Endocrinol Metab, 98, pp.4493~4498 (2013)
- Gersak K, "Low-level X chromosome mosaicism in women with sporadic premature ovarian failure", Reprod Biomed Online, 22, pp.399~403 (2011)