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간농양에 의한 패혈성 합병증과 동반된 진행성 위암

Liver abscess and septic complications associated with advanced gastric cancer

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초록

Pyogenic liver abscess with metastatic septic complications is a rare and serious infectious disease if not treated properly. Pyogenic liver abscesses are caused by bacterial, fungal, or parasitic organisms. Escherichia coli used to be the predominant causative agent, but Klebsiella pneumoniae emerged as a major cause in the 1990s. Liver abscesses are caused by hepatic invasion via many routes, such as, the biliary tree, portal vein, hepatic artery, direct extension, or penetrating trauma. Furthermore, diabetes mellitus and malignant conditions are established important risk factors of K. pneumoniae liver abscesses and of septic metastasis, and several recent studies have asserted that K. pneumoniae liver abscess might be a presentation of occult or silent colon cancer. We report a case of K. pneumoniae liver abscess, metastatic septic pulmonary embolism, and endophthalmitis associated with diabetes and advanced gastric cancer.

Abstract

Pyogenic liver abscess with metastatic septic complications is a rare and serious infectious disease if not treated properly. Pyogenic liver abscesses are caused by bacterial, fungal, or parasitic organisms. Escherichia coli used to be the predominant causative agent, but Klebsiella pneumoniae emerged as a major cause in the 1990s. Liver abscesses are caused by hepatic invasion via many routes, such as, the biliary tree, portal vein, hepatic artery, direct extension, or penetrating trauma. Furthermore, diabetes mellitus and malignant conditions are established important risk factors of K. pneumoniae liver abscesses and of septic metastasis, and several recent studies have asserted that K. pneumoniae liver abscess might be a presentation of occult or silent colon cancer. We report a case of K. pneumoniae liver abscess, metastatic septic pulmonary embolism, and endophthalmitis associated with diabetes and advanced gastric cancer.

참고문헌 (11)

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  6. Huang WK, "Higher rate of colorectal cancer among patients with pyogenic liver abscess with Klebsiella pneumoniae than those without: an 11-year follow-up study", Colorectal Dis, 14, pp.e794~e801 (2012)
  7. Zenda T, "Septic pulmonary emboli secondary to pyogenic liver abscess in a diabetic patient", Intern Med, 34, pp.42~45 (1995)
  8. Yang CS, "Endogenous Klebsiella endophthalmitis associated with pyogenic liver abscess", Ophthalmology, 114, pp.876~880 (2007)
  9. Yang PW, "Pyogenic liver abscess associated with septic pulmonary embolism", J Chin Med Assoc, 71, pp.442~447 (2008)
  10. Ye R, "Clinical characteristics of septic pulmonary embolism in adults: a systematic review", Respir Med, 108, pp.1~8 (2014)
  11. Lai HC, "Cryptogenic pyogenic liver abscess as a sign of colorectal cancer: a population-based 5-year follow-up study", Liver Int, 30, pp.1387~1393 (2010)

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