갑상선기능항진증과 열결절로 나타난 갑상선유두암 1예
Papillary Thyroid Carcinoma Presented as a Hot Nodule with Hyperthyroidism
0
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
We report a case of a 74-year-old woman who was incidentally found to have a single thyroid nodule. Laboratory evaluation showed undetectable serum thyroid stimulating hormone and elevated free thyroxine levels. 99mTc thyroid scan showed a hyperfunctioning autonomous nodule in a right lobe of the thyroid. Thyroid ultrasonography showed a 2.2 cm sized nonhomogeneous spiculated nodule with microcalcification, and which was identical with the hyperfunctioning nodule confirmed in thyroid scan by 99mTc single photon emission computed tomography/computed tomography. Fine needle aspiration was done, and cytology reported as suspicious of malignancy. The patient underwent total thyroidectomy with central neck dissection, and pathology was consistent with papillary thyroid carcinoma. This case report demonstrates that diagnosis of a hyperfunctioning autonomous thyroid nodule does not preclude the possibility of thyroid cancer. Clinicians should consider further evaluation such as ultrasonography and fine needle aspiration in patients with hyperfunctioning autonomous nodules.
Abstract
We report a case of a 74-year-old woman who was incidentally found to have a single thyroid nodule. Laboratory evaluation showed undetectable serum thyroid stimulating hormone and elevated free thyroxine levels. 99mTc thyroid scan showed a hyperfunctioning autonomous nodule in a right lobe of the thyroid. Thyroid ultrasonography showed a 2.2 cm sized nonhomogeneous spiculated nodule with microcalcification, and which was identical with the hyperfunctioning nodule confirmed in thyroid scan by 99mTc single photon emission computed tomography/computed tomography. Fine needle aspiration was done, and cytology reported as suspicious of malignancy. The patient underwent total thyroidectomy with central neck dissection, and pathology was consistent with papillary thyroid carcinoma. This case report demonstrates that diagnosis of a hyperfunctioning autonomous thyroid nodule does not preclude the possibility of thyroid cancer. Clinicians should consider further evaluation such as ultrasonography and fine needle aspiration in patients with hyperfunctioning autonomous nodules.
참고문헌 (9)
- Hegedus L, "Clinical practice. The thyroid nodule", N Engl J Med, 351(17), pp.1764~1771 (2004)
- Haugen BR, "2015 American Thyroid Association Management Guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: The American Thyroid Association Guidelines Task Force on thyroid nodules and differentiated thyroid cancer", Thyroid, 26(1), pp.1~133 (2016)
- Mirfakhraee S, "A solitary hyperfunctioning thyroid nodule harboring thyroid carcinoma: review of the literature", Thyroid Res, 6(1), pp.7~ (2013)
- 이은선, "Hyperfunction Thyroid Nodules: Their Risk for Becoming or Being Associated with Thyroid Cancers", Korean Journal of Radiology, 14(4), pp.643~652 (2013), 대한영상의학회[DOI]
- Mircescu H, "Hyperfunctioning malignant thyroid nodule in an 11-year-old girl: pathologic and molecular studies", J Pediatr, 137(4), pp.585~587 (2000)
- Tfayli HM, "Papillary thyroid carcinoma in an autonomous hyperfunctioning thyroid nodule: case report and review of the literature", Thyroid, 20(9), pp.1029~1032 (2010)
- Kim WB, "Ultrasonographic screening for detection of thyroid cancer in patients with Graves' disease", Clin Endocrinol (Oxf), 60(6), pp.719~725 (2004)
- 김지현, "Papillary Thyroid Carcinoma Manifesting as an Autonomously Functioning Thyroid Nodule", Endocrinology and Metabolism, 27(1), pp.59~62 (2012), 대한내분비학회
- "Cancer", 1998, 2638~2648