A Case of Teratoma of Thyroid Gland in Adolescence
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Benign teratomas of the thyroid are very rare in adolescence and adults. In this review, we report a case of 14-year-old Korean girl with huge neck mass. She presented with anterior neck enlargement and compression symptom which was rapidly aggravated in 2 months. In physical examination, enlarged and firm right thyroid lobe was palpated and laboratory test of thyroid function was normal. In ultrasonography, right lobe was mainly occupied with a solid nodule size of 44×23×25 mm, showing markedly inhomogeneous hypoechogenicity. As fine needle aspiration cytology was non-diagnostic, lobectomy was done. Histological examination demonstrated that the tumor is benign thyroid teratoma composed of tissue from all three germ layers. When large thyroid nodule is detected in adolescence and malignancy could not be ruled out, final diagnosis should be made with surgical resection. And we should at least attentive for possibility of teratomas when ultrasonographic findings are suspicious.
Abstract
Benign teratomas of the thyroid are very rare in adolescence and adults. In this review, we report a case of 14-year-old Korean girl with huge neck mass. She presented with anterior neck enlargement and compression symptom which was rapidly aggravated in 2 months. In physical examination, enlarged and firm right thyroid lobe was palpated and laboratory test of thyroid function was normal. In ultrasonography, right lobe was mainly occupied with a solid nodule size of 44×23×25 mm, showing markedly inhomogeneous hypoechogenicity. As fine needle aspiration cytology was non-diagnostic, lobectomy was done. Histological examination demonstrated that the tumor is benign thyroid teratoma composed of tissue from all three germ layers. When large thyroid nodule is detected in adolescence and malignancy could not be ruled out, final diagnosis should be made with surgical resection. And we should at least attentive for possibility of teratomas when ultrasonographic findings are suspicious.
참고문헌 (20)
- Fan SQ, "Thyroid teratoma in an 11-month-old infant", Int J Surg, 6(6), pp.462~464 (2008)
- 김지영, "부신 기형종 1예", Endocrinology and Metabolism, 26(3), pp.272~275 (2011), 대한내분비학회
- 옥찬영, "Benign Teratoma of the Thyroid Gland", Endocrinology and Metabolism, 28(2), pp.144~148 (2013), 대한내분비학회
- Nishihara E, "Benign thyroid teratomas manifest painful cystic and solid composite nodules: three case reports and a review of the literature", Endocrine, 30(2), pp.231~236 (2006)
- Oka K, "Congenital cervical immature teratoma arising in the left lobe of the thyroid gland", APMIS, 115(1), pp.75~79 (2007)
- Barksdale EM Jr, "Teratomas in infants and children", Curr Opin Pediatr, 21(3), pp.344~349 (2009)
- Kimler SC, "Primary malignant teratoma of the thyroid: case report and literature review of cervical teratomas in adults", Cancer, 42(1), pp.311~317 (1978)
- Thompson LD, "Primary thyroid teratomas: a clinicopathologic study of 30 cases", Cancer, 88(5), pp.1149~1158 (2000)
- Saphir O, "Teratoma of the neck", Am J Pathol, 5(3), pp.313~223 (1929)
- Bale GF, "Teratoma of the neck in the region of the thyroid gland; a review of the literature and report of 4 cases", Am J Pathol, 26(4), pp.565~579 (1950)
- Sommerlad BC, "Physiological activity in mediastinal teratomata", Thorax, 30(5), pp.510~515 (1975)
- Kallis P, "Exocrine pancreatic function in mediastinal teratomata: an aid to preoperative diagnosis?", Ann Thorac Surg, 54(4), pp.741~743 (1992)
- Schmitz H, "Ultrasound diagnosis of benign teratoma of the thyroid gland", Bildgebung, 57(3-4), pp.93~95 (1990)
- Pinchot SN, "Accuracy of fine-needle aspiration biopsy for predicting neoplasm or carcinoma in thyroid nodules 4 cm or larger", Arch Surg, 144(7), pp.649~655 (2009)
- McCoy KL, "The incidence of cancer and rate of false-negative cytology in thyroid nodules greater than or equal to 4 cm in size", Surgery, 142(6), pp.837~844 (2007)
- Yoon JH, "The diagnostic accuracy of ultrasound-guided fine-needle aspiration biopsy and the sonographic differences between benign and malignant thyroid nodules 3 cm or larger", Thyroid, 21(9), pp.993~1000 (2011)
- Kuru B, "The falsenegative rate of fine-needle aspiration cytology for diagnosing thyroid carcinoma in thyroid nodules", Langenbecks Arch Surg, 395(2), pp.127~132 (2010)
- Wharry LI, "Thyroid nodules (>", =4 cm): can ultrasound and cytology reliably exclude cancer?, 2014, pp.38(3), 614~621
- Gupta A, "A standardized assessment of thyroid nodules in children confirms higher cancer prevalence than in adults", J Clin Endocrinol Metab, 98(8), pp.3238~3245 (2013)
- Colton JJ, "Teratomas of the neck in adults", Arch Otolaryngol, 104(5), pp.271~272 (1978)
