Thyroid Hemiagenesis Associated with Papillary Thyroid Carcinoma
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Thyroid hemiagenesis is a rare congenital anomaly that is caused by a developmental defect of a thyroid. Previous reports indicate that thyroid cancer associated with hemiagenesis is extremely rare. A 47-year-old woman presented with single nodule in the right thyroid gland that was incidentally detected during a routine medical checkup. Ultrasonography showed a 1.5×1.2 cm sized ill-defined irregular hypoehoic nodule in the right thyroid and the isthmus was present. However, the left thyroid was not seen and thyroid was disconnected at left paraisthmic area. Fine-needle aspiration cytology confirmed that the right thyroid nodule was papillary thyroid carcinoma. Total thyroidectomy with bilateral central compartment node dissection was performed. Permanent pathologic finding was 1.3×1 cm sized classical type papillary thyroid carcinoma with nodular hyperplasia. There was extensive lymphatic invasion and 3 metastatic lymph nodes out of 4 in central compartment. In conclusion, although thyroid hemiagenesis associated with thyroid carcinoma is extremely rare, treatment strategy is not different with patients with normal anatomy. And the possibility of developing a thyroid carcinoma should be considered in patients with hemiagenesis. Furthermore, it requires awareness of anatomical difference around the thyroid gland during operation.
Abstract
Thyroid hemiagenesis is a rare congenital anomaly that is caused by a developmental defect of a thyroid. Previous reports indicate that thyroid cancer associated with hemiagenesis is extremely rare. A 47-year-old woman presented with single nodule in the right thyroid gland that was incidentally detected during a routine medical checkup. Ultrasonography showed a 1.5×1.2 cm sized ill-defined irregular hypoehoic nodule in the right thyroid and the isthmus was present. However, the left thyroid was not seen and thyroid was disconnected at left paraisthmic area. Fine-needle aspiration cytology confirmed that the right thyroid nodule was papillary thyroid carcinoma. Total thyroidectomy with bilateral central compartment node dissection was performed. Permanent pathologic finding was 1.3×1 cm sized classical type papillary thyroid carcinoma with nodular hyperplasia. There was extensive lymphatic invasion and 3 metastatic lymph nodes out of 4 in central compartment. In conclusion, although thyroid hemiagenesis associated with thyroid carcinoma is extremely rare, treatment strategy is not different with patients with normal anatomy. And the possibility of developing a thyroid carcinoma should be considered in patients with hemiagenesis. Furthermore, it requires awareness of anatomical difference around the thyroid gland during operation.
참고문헌 (20)
- Lipin R, "Thyroid hemiagenesis", J La State Med Soc, 164(4), pp.205~206 (2012)
- Sari O, "Thyroid hemiagenesis", Clin Nucl Med, 25(10), pp.766~768 (2000)
- Lee YS, "Thyroid hemiagenesis associated with thyroid adenomatous hyperplasia and papillary thyroid carcinoma", Thyroid, 18(3), pp.381~382 (2008)
- Pizzini AM, "Thyroid hemiagenesis and incidentally discovered papillary thyroid cancer: case report and review of the literature", J Endocrinol Invest, 28(1), pp.66~71 (2005)
- Wang J, "Thyroid hemiagenesis associated with medullary or papillary carcinoma: report of cases", Head Neck, 36(11), pp.E106~E111 (2014)
- Maiorana R, "Thyroid hemiagenesis: prevalence in normal children and effect on thyroid function", J Clin Endocrinol Metab, 88(4), pp.1534~1536 (2003)
- Shabana W, "Prevalence of thyroid hemiagenesis: ultrasound screening in normal children", Eur J Pediatr, 159(6), pp.456~458 (2000)
- Huang SM, "Right thyroid hemiagenesis associated with papillary thyroid cancer and an ectopic prelaryngeal thyroid: a case report", J Formos Med Assoc, 101(5), pp.368~371 (2002)
- Kim B, "Means of monitoring the course of postoperative inflammatory processes in the abdominal cavity", Vestn Akad Med Nauk SSSR, (6), pp.46~48 (1981)
- McHenry CR, "Congenital thyroid hemiagenesis", Am Surg, 61(7), pp.634~638 (1995)
- Khatri VP, "Papillary adenocarcinoma in thyroid hemiagenesis", Head Neck, 14(4), pp.312~315 (1992)
- Shaha AR, "Thyroid hemiagenesis", J Surg Oncol, 65(2), pp.137~140 (1997)
- 박재영, "갑상선 미세 유두선암과 동반된 갑상선 반쪽 무형성증", 대한외과학회지, 78(2), pp.116~118 (2010), 대한외과학회
- Hamburger JI, "Thyroidal hemiagenesis. Report of a case and comments on clinical ramifications", Arch Surg, 100(3), pp.319~320 (1970)
- Harada T, "Aplasia of one thyroid lobe", Am J Surg, 124(5), pp.617~619 (1972)
- Greening WP, "Hemiagenesis of the thyroid gland", Br J Surg, 67(6), pp.446~448 (1980)
- Park SG, "Thyroid hemiagenesis and ectopic thymus at thyroid bed, and papillary cancer in opposite thyroid lobe with hyperthyroidism", J Korean Surg Soc, 58(3), pp.433~437 (2000)
- 남예모, "갑상선 유두암과 동반된 갑상선 반쪽 무형성증 1예", 대한이비인후과학회지 두경부외과학, 54(8), pp.557~559 (2011), 대한이비인후과학회
- Karatag GY, "Coexistence of thyroid hemiagenesis, nodular goitre and papillary carcinoma", Kulak Burun Bogaz Ihtis Derg, 23(2), pp.115~118 (2013)
- Campenni A, "Thyroid hemiagenesis, Graves' disease and differentiated thyroid cancer: a very rare association: case report and review of literature", Hormones (Athens), 14(3), pp.451~458 (2015)