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A Case of Severe Thyrotoxicosis Caused by Graves’ Disease Presenting with Myasthenic Crisis

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초록

Thyrotoxicosis due to autoimmune thyroid disease occurs in approximately 5% to 10% of patients with myasthenia gravis (MG), whereas the incidence of MG in patients with Graves’ disease is much less at approximately 0.2%. Recently, we experienced a 40-year-old male patient diagnosed with thyroid storm with severe respiratory failure and lower extremity weakness. At first, he was diagnosed with Graves’ disease and critical illness neuropathy. His thyroid function was improved by anti-thyroid drug, but his neurologic function aggravated at the same time. He accordingly diagnosed with myasthenia gravis. We studied that when we should examine the neurologic function from this case. Our case highlights the importance of investigating muscle weakness or other neurologic problems in the thyrotoxic patient during their management.

Abstract

Thyrotoxicosis due to autoimmune thyroid disease occurs in approximately 5% to 10% of patients with myasthenia gravis (MG), whereas the incidence of MG in patients with Graves’ disease is much less at approximately 0.2%. Recently, we experienced a 40-year-old male patient diagnosed with thyroid storm with severe respiratory failure and lower extremity weakness. At first, he was diagnosed with Graves’ disease and critical illness neuropathy. His thyroid function was improved by anti-thyroid drug, but his neurologic function aggravated at the same time. He accordingly diagnosed with myasthenia gravis. We studied that when we should examine the neurologic function from this case. Our case highlights the importance of investigating muscle weakness or other neurologic problems in the thyrotoxic patient during their management.

참고문헌 (11)

  1. Tanwani LK, "Myasthenia gravis in conjunction with Graves'disease: a diagnostic challenge", Endocr Pract, 7(4), pp.275~278 (2001)
  2. Potagas C, "Myasthenia gravis: changes observed in a 30-years retrospective clinical study of a hospital-based population", J Neurol, 251(1), pp.116~117 (2004)
  3. McEachern D, "The relationship to hyperthyroidism to myasthenia gravis", J Clin Endocrinol Metab, 8(10), pp.842~850 (1948)
  4. Chiha M, "Thyroid Storm: An Updated Review", J Intensive Care Med (2013)
  5. Christensen PB, "Associated autoimmune diseases in myasthenia gravis. A population-based study", Acta Neurol Scand, 91(3), pp.192~195 (1995)
  6. Baretic M, "Myasthenic crisis as a side effect of methimazole therapy: case report", Acta Clin Croat, 49(1), pp.67~71 (2010)
  7. Marino M, "Mild clinical expression of myasthenia gravis associated with autoimmune thyroid diseases", J Clin Endocrinol Metab, 82(2), pp.438~443 (1997)
  8. Tsuda E, "Thyrotoxic myopathy mimicking myasthenic syndrome associated with thymic hyperplasia", Intern Med, 47(5), pp.445~447 (2008)
  9. Puvanendran K, "Neuromuscular transmission in thyrotoxicosis", J Neurol Sci, 43(1), pp.47~57 (1979)
  10. Nicolle MW, "Pseudo-myasthenia gravis and thymic hyperplasia in Graves' disease", Can J Neurol Sci, 26(3), pp.201~203 (1999)
  11. Kirmani JF, "Myasthenic crisis", Curr Treat Options Neurol, 6(1), pp.3~15 (2004)

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