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Subacute Thyroiditis Developed While Waiting for Papillary Thyroid Cancer Surgery: Pathologically Proven Two Cases

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초록

Co-existence of subacute thyroiditis and papillary thyroid cancer (PTC) is rarely reported. We have recentlyexperienced interesting cases of subacute thyroiditis, which developed while waiting for elective surgery of thyroidcancer in two patients. Two women, aged 52 and 55 years, suspected or diagnosed as PTC complained of anteriorneck pain and febrile sensation several weeks before the scheduled surgery. Both cases showed elevated serumthyroid hormones and erythrocyte sedimentation rate, and decreased thyroid-stimulating hormone. Ill-definedhypoechoic lesions on ultrasonography and decreased uptake on Tc-99m pertechnetate scan were noted in bothlobes. Total thyroidectomy for PTC was performed after relief of symptoms either by steroid or non-steroidanti-inflammatory drug treatment. Pathologic evaluation of surgical specimen revealed multinucleated giant cellsand mononuclear cell infiltration. Pathognomic findings of subacute thyroiditis in addition to PTC were observedin both cases.

Abstract

Co-existence of subacute thyroiditis and papillary thyroid cancer (PTC) is rarely reported. We have recentlyexperienced interesting cases of subacute thyroiditis, which developed while waiting for elective surgery of thyroidcancer in two patients. Two women, aged 52 and 55 years, suspected or diagnosed as PTC complained of anteriorneck pain and febrile sensation several weeks before the scheduled surgery. Both cases showed elevated serumthyroid hormones and erythrocyte sedimentation rate, and decreased thyroid-stimulating hormone. Ill-definedhypoechoic lesions on ultrasonography and decreased uptake on Tc-99m pertechnetate scan were noted in bothlobes. Total thyroidectomy for PTC was performed after relief of symptoms either by steroid or non-steroidanti-inflammatory drug treatment. Pathologic evaluation of surgical specimen revealed multinucleated giant cellsand mononuclear cell infiltration. Pathognomic findings of subacute thyroiditis in addition to PTC were observedin both cases.

참고문헌 (19)

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