Giant Parathyroid Adenomas: Differential Aspects Compared to Atypical Parathyroid Adenomas
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Primary hyperparathyroidism is a common diagnosis, often caused by a parathyroid adenoma, which can be resolved with surgical excision. However, pre-operative diagnosis of the causative adenoma may be challenging given the overlapping presentations and laboratory findings in typical, giant, and atypical parathyroid adenomas. In this case series, we describe one of the largest giant parathyroid adenomas excised in the United States and compare its presentation to that of an atypical parathyroid adenoma. Using this comparison, we aim elucidate the diagnostic value of various presentation characteristics, such as adenoma size, mass effect, symptom burden, and biochemical derangements.
Abstract
Primary hyperparathyroidism is a common diagnosis, often caused by a parathyroid adenoma, which can be resolved with surgical excision. However, pre-operative diagnosis of the causative adenoma may be challenging given the overlapping presentations and laboratory findings in typical, giant, and atypical parathyroid adenomas. In this case series, we describe one of the largest giant parathyroid adenomas excised in the United States and compare its presentation to that of an atypical parathyroid adenoma. Using this comparison, we aim elucidate the diagnostic value of various presentation characteristics, such as adenoma size, mass effect, symptom burden, and biochemical derangements.
참고문헌 (9)
- "Surgical endocrinology" (2013)[URL]
- Spanheimer PM, "Do giant parathyroid adenomas represent a distinct clinical entity?", Surgery, 154, pp.714~718 (2013)
- Ghemigian A, "Primary hyperparathyroidism-related giant parathyroid adenoma(review)", Exp Ther Med, 23, pp.88~ (2022)
- Galani A, "Atypical parathyroid adenoma : clinical and anatomical pathologic features", World J Surg Oncol, 19, pp.19~ (2021)
- Cetani F, "Atypical parathyroid adenomas : challenging lesions in the differential diagnosis of endocrine tumors", Endocr Relat Cancer, 26, pp.R441~64 (2019)
- Aziz H, "Giant parathyroid adenoma versus parathyroid carcinoma : differentiating two entities", J ASEAN Fed Endocr Soc, 36, pp.104~107 (2021)
- Walker MD, "Primary hyperparathyroidism", Nat Rev Endocrinol, 14, pp.115~125 (2018)
- Al-Hassan MS, "Giant parathyroid adenoma : a case report and review of the literature", J Med Case Reports, 13, pp.332~ (2019)
- Parfitt AM, "Asymptomatic primary hyperparathyroidism discovered by multichannel biochemical screening : clinical course and considerations bearing on the need for surgical intervention", J Bone Miner Res, 6(Suppl 2), pp.S97~101 (1991)
