비강을 침범한 Wegener씨 육아종증
Wegener’s Granulomatosis Involving Nasal Cavity
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Abstract
Background and Objectives：Wegeners granulomatosis is a chronic multisystem vasculitis. The otolaryngologist has an impor-we analyze seven cases of Wegeners granulomatosis involving nasal cavity and describe clinical features, laboratory findings, treatments and outcomes. Materials and Method：Seleced for this study were 7 inpatients with Wegeners granulomatosis trea-ted at the department of otolaryngology of Korea University Medical Center from January, 1985 and December, 2002. Their clinicopathologic records were reviewed retrospectively. Results：tion, serous and blody nasal discharge, septal perforation and sadle nose. All patients showed positive cytoplasmic antineutrophil cytoplasmic antibody (c-ANCA) and an elevated erythrocyte sedimentation rate (ESR). Wegeners granulomatosis was confir-med by the results of nasal mucosal biopsy performed in all patients. Conclusion：If multiple and large biopsy sites were selected e nasal mucosa is the most comonly afected site in Wegeners granulomatosis and nasal cavity is an easily acesible biopsy site.
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