두경부암종의 경부재발 치료 성적에 영향을 미치는 인자
Outcomes and Affecting Factors in the Management of Regional Recurrencein Head & Neck Squamous Cell Carcinoma
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Abstract
Background and Objectives：Regional recurrence of head and neck squamous cell carcinoma (HNSCC) is the most commonsingle type of treatment failure, and thus a challenging problem for the clinician. When planning management of regional recurrence,the grave outcome of the recurrence itself, and benefits and morbidity owing to the intervention must be taken into account.We analyzed the factors affecting salvage treatment outcomes of regional recurrence in head & neck squamous cell carcinoma.Subjects and Method：A retrospective analysis of medical records over a 10 year period (1994-2003) was conducted. Sixtytwopatients with regional and locoregional recurrence were identified. Patients with local recurrence or distant metastasis wereexcluded. Results：The median age of the population was 62 years. Sixty percent of the cases were regional, and the remainderswere locoregional recurrences. The median time of recurrence was 16 months with an overall survival rate of 46.1%. Recurrencein a surgically virginal neck was associated with a favorable outcome. Factors associated with poor outcomes were node positiveat initial presentation, neck dissection at initial treatment, recurrence at contralateral neck, incorporation of chemotherapy forsalvage treatment, and subsequent recurrence after salvage treatment. Conclusion：In the management of patients with regionalrecurrence of HNSCC, the factors mentioned above should be taken into consideration regarding patient selection, salvage managementplan, and patient counseling. (Korean J Otolaryngol 2006;49:807-11)
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