집먼지 진드기 알레르기 비염의 면역치료의 결과에 대한 장기추적
Long-term Follow-up of Immunotherapy in Allergic Rhinitis to House Dust Mite
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Abstract
Background and Objectives：This study was to evaluate the long-term efect of immunotherapy on the allergic rhinitis patients to house dust mite (HDM) patients. Subjects and Method：Sixty-five patients were treated for allergic rhinitis in the allergy clinic. Every patient underwent imunotherapy for 3 to 5 years and did not receive any additional treatments after the completion of the initial one. The survey on the symptom improvement and the patients satisfaction was carried out 3 and 10 years after the imunotherapy treatment. The results of skin prick test for each individual were analyzed before, 3 and 10 years after the im-munotherapy, respectively. Results：Overall symptom improvement surveyed 10 years after the imunotherapy decreased compared with that taken after 3 years of the treatment (p<0.05). In particular, symptom improvements on sneezing, itching (p<0.05). Patients satisfaction level was 64.6% after 3 years and 49.2% after 10 years of the imunotherapy treatment. Skin prick test reactivity was significantly decreased after 3 years of the treatment compared to before the treatment. Although skin prick test reactivity measured in 10 years after immunotherapy increased compared with that measured in 3 years after, there was little statistical significance when compared with the reactivity before the treatment. Conclusion：The immunotherapy has long term eficacy on allergic rhinitis to HDM. However, the eficacy (Korean J Otorhinolaryngol-Head Neck Surg 2007 ;50 : 1006-11)
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