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논문KCI 등재

레이저 성대 절제술을 시행한 조기 성문암 환자의 치료 결과 및 전암성 병변으로 부터의 악성 변환 관찰

Result of Laser Cordectomy in Early Glottic Cancer and Observation of Malignant Transformation from Precancerous Lesion

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주제분류이비인후과학

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Background and Objectives Laser cordectomy has been widely acknowledged to have advantages for the treatment of early glottic carcinoma. This study was performed to assess the results of laser cordectomy for its oncologic safeness, time-effectiveness, and to report a few interesting precancerous cases that have progressed to glottic cancer. Subjects and Method Subjects (47) who had undergone laser cordectomy for the treatment of early glottic cancer from April 2006 to July 2009 were enrolled in this study. We analyzed the oncologic outcomes, the duration of hospital treatment after the surgery, and postoperative complications by reviewing of medical records. Results For 47 cases, the mean age was 66 years and the mean follow up period was 22.6months. The mean duration of treatment was 1.9 days. Among them, 24 cases were classified into T1a, 12 T1b, and 2 T2. Local recurrence was observed in 2 cases, so salvage treatments, such as radiation therapy or near total laryngectomy, were performed, and both of them were alive in the disease-free state. The most common complication was anterior commissure web, which was observed in 6 cases (15.8%), followed by granuloma observed in 5 cases (13.1%). Serious complications such as aspiration, respiratory distress, and dysphagia were not found in any of 47 cases. Also, we could observe 3 cases in which the precancerous glottic lesion had progressed to glottic carcinoma over a long period of time. Conclusion Laser cordectomy might be the treatment of choice for patient’s convenience because of its excellent oncologic outcomes, low morbidity, and time-effectiveness. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:425-9

Abstract

Background and Objectives Laser cordectomy has been widely acknowledged to have advantages for the treatment of early glottic carcinoma. This study was performed to assess the results of laser cordectomy for its oncologic safeness, time-effectiveness, and to report a few interesting precancerous cases that have progressed to glottic cancer. Subjects and Method Subjects (47) who had undergone laser cordectomy for the treatment of early glottic cancer from April 2006 to July 2009 were enrolled in this study. We analyzed the oncologic outcomes, the duration of hospital treatment after the surgery, and postoperative complications by reviewing of medical records. Results For 47 cases, the mean age was 66 years and the mean follow up period was 22.6months. The mean duration of treatment was 1.9 days. Among them, 24 cases were classified into T1a, 12 T1b, and 2 T2. Local recurrence was observed in 2 cases, so salvage treatments, such as radiation therapy or near total laryngectomy, were performed, and both of them were alive in the disease-free state. The most common complication was anterior commissure web, which was observed in 6 cases (15.8%), followed by granuloma observed in 5 cases (13.1%). Serious complications such as aspiration, respiratory distress, and dysphagia were not found in any of 47 cases. Also, we could observe 3 cases in which the precancerous glottic lesion had progressed to glottic carcinoma over a long period of time. Conclusion Laser cordectomy might be the treatment of choice for patient’s convenience because of its excellent oncologic outcomes, low morbidity, and time-effectiveness. Korean J Otorhinolaryngol-Head Neck Surg 2010;53:425-9

참고문헌 (20)

  1. Gallo A, "CO2 Laser cordectomy for early-stage glottis carcinoma: a long-term follow up of 156 cases", Laryngoscope, 112(2), pp.370~374 (2002)
  2. 박지훈, "초기 성문암에서 레이저 성대절제술과 방사선치료 결과", 대한이비인후과학회지 두경부외과학, 45(2), pp.159~163 (2002), 대한이비인후과학회
  3. 태경, "조기 성무암종에서 경구강 CO₂레이저 성대절제술의 의의", 대한이비인후과학회지 두경부외과학, 49(5), pp.538~542 (2006), 대한이비인후과학회
  4. de Campora E, "External versus endoscopic approach in the surgical treatment of glottic cancer", Eur Arch Otorhinolaryngol, 258(10), pp.533~536 (2001)
  5. 손성환, "경구강 접근을 통한 CO2 레이저 후두 부분 절제술", 대한이비인후과학회지 두경부외과학, 48(4), pp.489~495 (2005), 대한이비인후과학회
  6. Remacle M, "Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society", Eur Arch Otorhinolaryngol, 257(4), pp.227~231 (2000)
  7. 정필상, "T1 성문암에서 방사선치료와 레이저 성대절제술의 비교분석", 대한이비인후과학회지 두경부외과학, 48(9), pp.1161~1165 (2005), 대한이비인후과학회
  8. Cragle SP, "Laser cordectomy or radiotherapy: cure rates, communication, and cost", Otolaryngol Head Neck Surg, 108(6), pp.648~654 (1993)
  9. Strong MS, "Laser surgery in the larynx. Early clinical experience with continuous CO2 laser", Ann Otol Rhinol Laryngol, 81(6), pp.791~798 (1972)
  10. Steiner W, "Results of curative laser microsurgery of laryngeal carcinoma", Am J Otolaryngol, 14(2), pp.116~121 (1993)
  11. Motta G, "T1-T2-T3 glottic tumors: fifteen years experience with CO2 laser", Acta Otolaryngol Suppl, 527, pp.155~159 (1997)
  12. Department of otorhinolaryngology, "Seoul national university college of medicine. Laser surgery for laryngeal cancer", Seoul symposium, 통권 : 13, pp.174~186 (2007)
  13. Wolfenberger M, "Endoscopic laser surgery for early glottic carcinoma: a clinical and experimental study", Laryngoscope, 100, pp.1100~1105 (1990)
  14. Thomas JV, "Recurrence after endoscopic management of early(T1) glottic carcinoma", Laryngoscope, 104(9), pp.1099~1104 (1994)
  15. Roh JL, "The utility of second-look operation after laser microresection of glottis carcinoma involving the anterior commissure", Laryngoscope, 118(8), pp.1400~1404 (2008)
  16. Friedmann I, "Nose, throat and ears. 3rd ed" (1986), Churchill Livingstone
  17. Ricci G, "Retrospective study on precancerous laryngeal lesions: long-term follow up", Acta Otorhinolaryngol Ital, 23(5), pp.362~367 (2003)
  18. Mendenhall WM, "Management of Tis, T1 and T2 squamous carcinoma of the glottic larynx", Am J Otolaryngol, 15(4), pp.250~257 (1994)
  19. Motta G, "Microlaryngoscopy treatment of laryngeal dysplasia with CO2 laser", Acta Otorhinolaryngol Ital, 21(1), pp.32~43 (2001)
  20. Minni A, "Treatment with laser CO2 cordectomy and clinical implications in management of mild and moderate laryngeal precancerosis", Eur Arch Otorhinolaryngol, 265(2), pp.189~193 (2008)

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