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논문KCI 등재

조기 성문암 환자에서 레이저 절제술 또는 방사선 치료 후 음성학적 결과 비교

Comparison of Voice Outcomes in Early Glottic Cancer Patients after Laser Surgery or Radiotherapy

김동훈|이수현|김준현|김우진|이소윤|박영학|안수현
대한이비인후과학회 (Korean Society of Otorhinolaryngology-Head and Neck Surgery)|2012.11|대한이비인후과학회지 두경부외과학 (Korean Journal of Otorhinolaryngology-Head and Neck Surgery)|제55권 제11호|pp. 701-706|DOI http://dx.doi.org/10.3342/kjorl-hns.2012.55.11.701

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키워드

VoiceRadiotherapyRadiation doseEarly glottic cancerLaser surgery
주제분류이비인후과학

초록

Background and Objectives Radiotherapy and laser surgery are the main treatment modalities for early glottic cancer. However, which treatment has better voice outcome is unclear. Few studies have considered the effect of radiation dose on voice outcomes after radiotherapy. The purpose of this study was to compare voice outcomes in early glottic cancer patients between two treatment modalities and to identify whether radiation dose affects voice outcomes. Subjects and Method From January 1995 to December 2010, 66 patients with the early glottic cancer who underwent laser surgery (n=27) or radiotherapy (n=39) were retrospectively investigated. Voice quality was assessed using Computerized Speech Lab and F0, Jitter, Shimmer and noise to harmonic ratio were evaluated. For aerodynamic test, maximum phonation time was also evaluated. Results F0 differed statistically between the laser surgery group and radiotherapy group. In laser surgery group, F0 was elevated after surgery. On the other hand, F0 decreased statistically after radiotherapy. In the radiotherapy group, the dose was statistically different between the lower and higher dose groups. In T2 stage disease, which received a higher radiation dose, voice outcomes were poorer than in T1a or T1b stage diseases. Conclusion In early glottic cancer, F0 differed statistically between the laser surgery group and the radiotherapy group: F0 decreased statistically after radiotherapy. In the radiotherapy group, voice quality was affected by radiation dose as the higher dose resulted in poorer voice outcomes.

Abstract

Background and Objectives Radiotherapy and laser surgery are the main treatment modalities for early glottic cancer. However, which treatment has better voice outcome is unclear. Few studies have considered the effect of radiation dose on voice outcomes after radiotherapy. The purpose of this study was to compare voice outcomes in early glottic cancer patients between two treatment modalities and to identify whether radiation dose affects voice outcomes. Subjects and Method From January 1995 to December 2010, 66 patients with the early glottic cancer who underwent laser surgery (n=27) or radiotherapy (n=39) were retrospectively investigated. Voice quality was assessed using Computerized Speech Lab and F0, Jitter, Shimmer and noise to harmonic ratio were evaluated. For aerodynamic test, maximum phonation time was also evaluated. Results F0 differed statistically between the laser surgery group and radiotherapy group. In laser surgery group, F0 was elevated after surgery. On the other hand, F0 decreased statistically after radiotherapy. In the radiotherapy group, the dose was statistically different between the lower and higher dose groups. In T2 stage disease, which received a higher radiation dose, voice outcomes were poorer than in T1a or T1b stage diseases. Conclusion In early glottic cancer, F0 differed statistically between the laser surgery group and the radiotherapy group: F0 decreased statistically after radiotherapy. In the radiotherapy group, voice quality was affected by radiation dose as the higher dose resulted in poorer voice outcomes.

참고문헌 (21)

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