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논문KCI 등재

후각장애 원인에 따른 Butanol Threshold Test와 Cross Cultural Smell Identification Test의 상관관계

The Correlation between Butanol Threshold Test (BTT) and Cross Cultural Smell Identification Test (CC-SIT) According to Causes of Olfactory Disorders

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참고문헌

키워드

주제분류이비인후과학

초록

Background and Objectives Olfaction is a critical function of our body that allows one to avoid potential dangers in daily living. Although there are numerous subjective and objective tests evaluating the olfactory function, there exist no studies assessing correlations among such tests for various causes of olfactory dysfunction, especially in Korea. Subjects and Method We collected the olfactory functional test results of 473 subjects who visited our outpatient clinic. We categorized these patients into 5 groups: head trauma, post-upper respiratory infection, chronic sinonasal disease, toxic exposure, and idiopathic. All patients were examined using the Butanol Threshold Test (BTT) and Cross Cultural Smell Identification Test (CC-SIT). The patients’ subjective symptoms were recorded using the Visual Analog Scale (VAS). Results The three tests showed significant correlations in different pairs (CC-SIT and BTT; r=0.512, p<0.001, BTT and VAS; r=0.558, p<0.001 and VAS & CC-SIT; r=0.567, p<0.001). Correlation results were lower in patients with olfactory disorders caused by an upper respiratory infection and head trauma than in those with olfactory disorders caused by sinonasal diseases. Conclusion The results from all three tests showed significant correlations with one another. CC-SIT and VAS score seem to represent the olfactory loss caused by sensorineural dysfunction better than BTT.

Abstract

Background and Objectives Olfaction is a critical function of our body that allows one to avoid potential dangers in daily living. Although there are numerous subjective and objective tests evaluating the olfactory function, there exist no studies assessing correlations among such tests for various causes of olfactory dysfunction, especially in Korea. Subjects and Method We collected the olfactory functional test results of 473 subjects who visited our outpatient clinic. We categorized these patients into 5 groups: head trauma, post-upper respiratory infection, chronic sinonasal disease, toxic exposure, and idiopathic. All patients were examined using the Butanol Threshold Test (BTT) and Cross Cultural Smell Identification Test (CC-SIT). The patients’ subjective symptoms were recorded using the Visual Analog Scale (VAS). Results The three tests showed significant correlations in different pairs (CC-SIT and BTT; r=0.512, p<0.001, BTT and VAS; r=0.558, p<0.001 and VAS & CC-SIT; r=0.567, p<0.001). Correlation results were lower in patients with olfactory disorders caused by an upper respiratory infection and head trauma than in those with olfactory disorders caused by sinonasal diseases. Conclusion The results from all three tests showed significant correlations with one another. CC-SIT and VAS score seem to represent the olfactory loss caused by sensorineural dysfunction better than BTT.

참고문헌 (17)

  1. Deems DA, "Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center", Arch Otolaryngol Head Neck Surg, 117(5), pp.519~528 (1991)
  2. Jung DH, "Clinical analysis of olfactory dysfunction", Korean J Rhinol, 2(2), pp.118~123 (1995)
  3. Shin SH, "Clinical value of olfactory function test following functional endoscopic sinus surgery", Korean J Otolaryngol-Head Neck Surg, 40(4), pp.568~573 (1997)
  4. Doty RL, "University of Pennsylvania Smell Identification Test: a rapid quantitative olfactory function test for the clinic", Laryngoscope, 94(2 Pt 1), pp.176~178 (1984)
  5. Hummel T, "‘Sniffin’ sticks’: olfactory performance assessed by the combined testing of odor identification, odor discrimination and olfactory threshold", Chem Senses, 22(1), pp.39~52 (1997)
  6. Takagi SF, "A standardized olfactometer in Japan. A review over ten years", Ann N Y Acad Sci, 510, pp.113~118 (1987)
  7. Doty RL, "Development of the 12-item Cross-Cultural Smell Identification Test (CC-SIT)", Laryngoscope, 106(3 Pt 1), pp.353~356 (1996)
  8. Hong SC, "Development of KVSS Test (Korean Version of Sniffin’ Sticks Test)", Korean J Otolaryngol-Head Neck Surg, 42(7), pp.855~860 (1999)
  9. Dhong HJ, "The usefulness of CC-SIT (Cross-Cultural Smell Identification Test) in Korea", Korean J Otolaryngol-Head Neck Surg, 43(7), pp.737~740 (2000)
  10. 최효근, "후각역치검사, 후각인지검사와 주관적 증상간의 상관관계", 대한이비인후과학회지 두경부외과학, 51(11), pp.1015~1019 (2008), 대한이비인후과학회
  11. Doty RL, "Office procedures for quantitative assessment of olfactory function", Am J Rhinol, 21(4), pp.460~473 (2007)
  12. 최윤석, "객관적인 후각 기능 평가를 위한 후각 전위 유발 검사", 대한이비인후과학회지 두경부외과학, 50(8), pp.672~676 (2007), 대한이비인후과학회
  13. Benninger MS, "Rhinitis, Sinusitis, and their relationship to allergies", Am J Rhinol, 6(2), pp.37~43 (1992)
  14. Schiffman SS, "Taste and smell losses in normal aging and disease", JAMA, 278(16), pp.1357~1362 (1997)
  15. Mott AE, "Topical corticosteroid treatment of anosmia associated with nasal and sinus disease", Arch Otolaryngol Head Neck Surg, 123(4), pp.367~372 (1997)
  16. Heilmann S, "Local and systemic administration of corticosteroids in the treatment of olfactory loss", Am J Rhinol, 18(1), pp.29~33 (2004)
  17. Duncan HJ, "Long-term follow-up of olfactory loss secondary to head trauma and upper respiratory tract infection", Arch Otolaryngol Head Neck Surg, 121(10), pp.1183~1187 (1995)

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